Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Antony A. Cooper"'
Autor:
Sophie L. Farrow, Sreemol Gokuladhas, William Schierding, Michael Pudjihartono, Jo K. Perry, Antony A. Cooper, Justin M. O’Sullivan
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract Genome wide association studies (GWAS) have identified a number of genomic loci that are associated with Parkinson’s disease (PD) risk. However, the majority of these variants lie in non-coding regions, and thus the mechanisms by which the
Externí odkaz:
https://doaj.org/article/777c62e53bcb4a74b6e99d11f4201189
Publikováno v:
npj Parkinson's Disease, Vol 8, Iss 1, Pp 1-7 (2022)
Abstract Parkinson’s disease (PD) research has largely focused on the disease as a single entity centred on the development of neuronal pathology within the central nervous system. However, there is growing recognition that PD is not a single entit
Externí odkaz:
https://doaj.org/article/7712410501b9492f88d330ad36f38a4e
Autor:
Boris Guennewig, Julia Lim, Lee Marshall, Andrew N. McCorkindale, Patrick J. Paasila, Ellis Patrick, Jillian J. Kril, Glenda M. Halliday, Antony A. Cooper, Greg T. Sutherland
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/7512accadacd4ae49e0b3c2a1bf67f69
Autor:
Boris Guennewig, Julia Lim, Lee Marshall, Andrew N. McCorkindale, Patrick J. Paasila, Ellis Patrick, Jillian J. Kril, Glenda M. Halliday, Antony A. Cooper, Greg T. Sutherland
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Tau pathology in Alzheimer’s disease (AD) spreads in a predictable pattern that corresponds with disease symptoms and severity. At post-mortem there are cortical regions that range from mildly to severely affected by tau pathology and neur
Externí odkaz:
https://doaj.org/article/3d30c932bbdf4fafba8d0669bc8e6e7e
Autor:
Daniel Ho, William Schierding, Sophie L. Farrow, Antony A. Cooper, Andreas W. Kempa-Liehr, Justin M. O’Sullivan
Publikováno v:
Frontiers in Genetics, Vol 12 (2022)
Parkinson’s disease (PD) is a complex neurodegenerative disease with a range of causes and clinical presentations. Over 76 genetic loci (comprising 90 SNPs) have been associated with PD by the most recent GWAS meta-analysis. Most of these PD-associ
Externí odkaz:
https://doaj.org/article/1baa78bf6e904c66ab792fe373977d8e
Autor:
Boris Guennewig, Julia Lim, Lee Marshall, Andrew N. McCorkindale, Patrick J. Paasila, Ellis Patrick, Jillian J. Kril, Glenda M. Halliday, Antony A. Cooper, Greg T. Sutherland
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/6e2b8d97c71f46e2b4eca4815f36ffcf
Publikováno v:
Parkinson's Disease, Vol 2012 (2012)
Parkinson’s Disease (PD) is a complex, chronic, progressive, and debilitating neurodegenerative disorder. Neither a cure nor effective long-term therapy exist and the lack of knowledge of the molecular mechanisms responsible for PD development is a
Externí odkaz:
https://doaj.org/article/7a1438bfb676454bbdb10a89449a45a4
Autor:
Sophie L Farrow, William Schierding, Sreemol Gokuladhas, Evgeniia Golovina, Tayaza Fadason, Antony A Cooper, Justin M O’Sullivan
Publikováno v:
Brain. 145:2422-2435
The latest meta-analysis of genome-wide association studies identified 90 independent variants across 78 genomic regions associated with Parkinson’s disease, yet the mechanisms by which these variants influence the development of the disease remain
Publikováno v:
International Journal of Digital Earth. 14:1897-1917
Publikováno v:
Transactions in GIS. 26:459-474