Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Antonius Song"'
Autor:
Brenda Burnham, Abraham Scaria, Samuel C. Wadsworth, Seng H. Cheng, Denise Woodcock, Catherine R. O'Riordan, Elton Kong, Antonius Song, Maryellen Mattingly, Shelley Nass
Publikováno v:
Human Gene Therapy Methods. 26:228-242
Recombinant adeno-associated viral (rAAV) vectors represent a novel class of biopharmaceutical drugs. The production of clinical-grade rAAV vectors for gene therapy would benefit from analytical methods that are able to monitor drug product quality w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf002dec946618254bc797779f1b04a3
https://doi.org/10.1089/hgtb.2015.048
https://doi.org/10.1089/hgtb.2015.048
Autor:
Tatyana V. Taksir, Jie Bu, Lamya S. Shihabuddin, Denise Griffiths, Catherine R. O'Riordan, James Dodge, Seng H. Cheng, Wendy Yang, Jennifer Clarke, Edward H. Schuchman, Gregory R. Stewart, Antonius Song, Michael A. Zhao, Marco A. Passini
Publikováno v:
Proceedings of the National Academy of Sciences. 102:17822-17827
Niemann-Pick type A disease is a lysosomal storage disorder caused by a deficiency in acid sphingomyelinase (ASM) activity. Previously we showed that storage pathology in the ASM knockout (ASMKO) mouse brain can be corrected by adeno-associated virus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0cfb135052fa7d53f7a80eef6f52278
https://doi.org/10.1073/pnas.0509062102
https://doi.org/10.1073/pnas.0509062102
Autor:
Malgorzata Przybylska, Jennifer D. Tousignant, I-Huan Wu, Seng H. Cheng, Hongmei Zhao, Antonius Song, Nelson S. Yew
Publikováno v:
Molecular Therapy. 1(3):255-262
An inflammatory response is invariably associated with administration of gene transfer complexes composed of cationic lipids and plasmid DNA (pDNA). In the lung, an influx of neutrophils and elevated levels of several proinflammatory cytokines such a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4afc24d5fea3fdbc16e08e6c5211a60c
Autor:
Bjorn A. Thorsrud, Dwayne Hill, Walter Meixner, Raoul Kopelman, Michael T. Miller, Zhong You Shi, Marion Hoyer, Susan L. R. Barker, Eric Monson, Antonius Song, Martin A. Philbert, Murphy Brasuel, Alex Ade, Steve Parus, R. L.-F. Lightle, Brian D. Athey, Heather A. Clark
Publikováno v:
Sensors and Actuators B: Chemical. 51:12-16
Described here are arguably the world's smallest stand-alone devices/sensors, consisting of multicomponent nano-spheres with radii as small as 10 nm, occupying ≈1 ppb of a typical mammalian cell’s volume. The probe is prepared from up to seven in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68fa922d1154cbbd7174932ae6581a78
https://doi.org/10.1016/s0925-4005(98)00212-3
https://doi.org/10.1016/s0925-4005(98)00212-3
Publikováno v:
Analytical Chemistry. 69:863-867
A fast and durable ratiometric pH microoptode that is highly accurate, precise, sensitive, reversible, and reproducible over the physiological ranges of pH, ionic strength, and temperature has been developed. The sensing site consists of 5 (and 6)-ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce23451cba69925c37f93101ed8288f
https://doi.org/10.1021/ac960917+
https://doi.org/10.1021/ac960917+
Publikováno v:
Advances in experimental medicine and biology. 723
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::41cff8f6997ec6db9c59f73d3ff38be1
https://pubmed.ncbi.nlm.nih.gov/22183380
https://pubmed.ncbi.nlm.nih.gov/22183380
Autor:
Matthew Adamowicz, Antonius Song, Samuel C. Wadsworth, Abraham Scaria, Catherine R. O'Riordan
Publikováno v:
Retinal Degenerative Diseases ISBN: 9781461406303
A cellular model was developed to investigate potential mechanisms of cell death in rod opsin retinitis pigmentosa (RP). This model is based on transient expression of the WT and mutant P23H rod opsin in human retinal pigmented epithelial cells (RPE)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ad81e79b3b39a344a389edce224112d
https://doi.org/10.1007/978-1-4614-0631-0_73
https://doi.org/10.1007/978-1-4614-0631-0_73
Autor:
Leocadia M. Mosquea, Seng H. Cheng, Nelson S. Yew, Antonius Song, Canwen Jiang, Adam J. Belanger, Andrew Leger, Allison Altobelli
Publikováno v:
Journal of bone and mineral metabolism. 28(5)
Studies examining the effects of hypoxia upon osteoclast biology have consistently revealed a stimulatory effect; both osteoclast differentiation and resorption activity have been shown to be enhanced in the presence of hypoxia. In the present study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f0847334d79c71b28935644fdd0a374
https://pubmed.ncbi.nlm.nih.gov/20300790
https://pubmed.ncbi.nlm.nih.gov/20300790
Autor:
Catherine R, O'Riordan, Antonius, Song
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 434
Bifunctional polyethylene glycol (PEG) molecules provide a novel approach to retargeting viral vectors without the need to genetically modify the vector. Modification of the surface of adenovirus with heterofunctional PEG allows further modification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e97ec48c6ac6de1e295bfa84ec9da56c
https://pubmed.ncbi.nlm.nih.gov/18470643
https://pubmed.ncbi.nlm.nih.gov/18470643
Publikováno v:
Gene Therapy Protocols ISBN: 9781603272476
Bifunctional polyethylene glycol (PEG) molecules provide a novel approach to retargeting viral vectors without the need to genetically modify the vector. Modification of the surface of adenovirus with heterofunctional PEG allows further modification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::136cc04b58bea15cf79a990b9c124808
https://doi.org/10.1007/978-1-60327-248-3_9
https://doi.org/10.1007/978-1-60327-248-3_9