Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Antonius M.J. VanDongen"'
Publikováno v:
Stem Cell Reports, Vol 8, Iss 4, Pp 856-869 (2017)
Summary: Although mutations in several genes with diverse functions have been known to cause amyotrophic lateral sclerosis (ALS), it is unknown to what extent causal mutations impinge on common pathways that drive motor neuron (MN)-specific neurodege
Externí odkaz:
https://doaj.org/article/2c65fbbf867b44dc8a9f67897bf1b1b6
Autor:
Lin Lin, Jonathan Göke, Engin Cukuroglu, Mark R. Dranias, Antonius M.J. VanDongen, Lawrence W. Stanton
Publikováno v:
Cell Reports, Vol 15, Iss 11, Pp 2411-2426 (2016)
The fact that Parkinson’s disease (PD) can arise from numerous genetic mutations suggests a unifying molecular pathology underlying the various genetic backgrounds. To address this hypothesis, we took an integrated approach utilizing in vitro disea
Externí odkaz:
https://doaj.org/article/82c6eb136bfd43bea69248dbc55712f3
Publikováno v:
Frontiers in Integrative Neuroscience, Vol 9 (2015)
In both humans and animals brief synchronizing bursts of epileptiform activity known as interictal epileptiform discharges (IEDs) can, even in the absence of overt seizures, cause transient cognitive impairments (TCI) that include problems with perce
Externí odkaz:
https://doaj.org/article/53448b985ada4d4b9b52db241d4c48b1
Autor:
Antonius M.J. VanDongen, Yuheng Jiang
New tools in optogenetics and molecular biology have culminated in recent studies which mark immediate-early gene (IEG)-expressing neurons as memory traces or engrams. Although the activity-dependent expression of IEGs has been successfully utilised
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3f57de717f3497d00bb85fa097480c7
https://doi.org/10.1101/2020.12.07.415109
https://doi.org/10.1101/2020.12.07.415109
Autor:
Yuheng Jiang, Antonius M.J. VanDongen
The immediate-early gene Arc is a master regulator of synaptic plasticity and plays a critical role in memory consolidation. However, there has not been a comprehensive analysis of the itinerary of Arc protein, linking its function at different subce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ec8c243b643ba68645c6ee436a9fea2
https://doi.org/10.1101/2020.11.10.376756
https://doi.org/10.1101/2020.11.10.376756
Autor:
Juan Yin, Antonius M.J. VanDongen
Advances in the development of three-dimensional (3D) brain organoids maintained in vitro have provided excellent opportunities to study brain development and neurodegenerative disorders, including Alzheimer's disease (AD). However, there remains a n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0d59bf81e3c063f39ee9eff8c4716be
https://doi.org/10.1101/2020.07.07.192781
https://doi.org/10.1101/2020.07.07.192781
Autor:
Yuheng Jiang, Antonius M.J. VanDongen
Publikováno v:
eNeuro
The activity-dependent expression of immediate-early genes (IEGs) has been utilised to label memory traces. However, their roles in engram specification are incompletely understood. Outstanding questions remain as to whether expression of IEGs can in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6efbdb4464133946845fc187a8d1ad84
https://doi.org/10.1523/eneuro.0540-20.2021
https://doi.org/10.1523/eneuro.0540-20.2021
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 8, Iss 4, Pp 856-869 (2017)
Stem Cell Reports, Vol 8, Iss 4, Pp 856-869 (2017)
Summary Although mutations in several genes with diverse functions have been known to cause amyotrophic lateral sclerosis (ALS), it is unknown to what extent causal mutations impinge on common pathways that drive motor neuron (MN)-specific neurodegen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b67237f7e4be40ba1c496d23ff279d2d
https://doi.org/10.1016/j.stemcr.2017.02.019
https://doi.org/10.1016/j.stemcr.2017.02.019
The immediate-early gene Arc is a master regulator of synaptic function and a critical determinant of memory consolidation. Arc protein is localized to excitatory synapses, where it controls AMPA receptor endocytosis, and to the nucleus, where it ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97c42d28c3fa7bedf38414ee2301e2f6
Autor:
Antonius M.J. VanDongen, Yee Sien Ng, Juan Zhou, Geoffrey Sithamparapillai Samuel, Joseph Lim, Nicodemus E. Oey
Publikováno v:
Journal of Central Nervous System Disease
Journal of Central Nervous System Disease, Vol 11 (2019)
Journal of Central Nervous System Disease, Vol 11 (2019)
Background: Diffusion tensor imaging (DTI) magnetic resonance imaging (MRI) measuring fractional anisotropy (FA) and axial diffusivity (AD) may be a useful biomarker for monitoring changes in white matter after stroke, but its associations with upper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de7f326cf0e56dcb1e7e952e9c2b9ec0
http://europepmc.org/articles/PMC6668170
http://europepmc.org/articles/PMC6668170