Advanced molecular characterization using Digital Spatial Profiling Technology on immuno-oncology targets in methylated compared with unmethylated IDH-wildtype glioblastoma

Autor: Jing Jing Gong, Yan Liang, Aled R. Daniels, Kathreena M Kurian, Yuqi Ren, Beatrice Lander, Antonis Tofias, Paul D. White, Xing Ren, Hannah Barber

Publikováno v: Neuro Oncol
Journal of Oncology
Journal of Oncology, Vol 2021 (2021)
Barber, H, Tofias, A, Lander, B, Daniels, A, Gong, J, Ren, Y, Ren, X, Liang, Y, White, P & Kurian, K M 2021, ' Advanced molecular characterization using Digital Spatial Profiling Technology on immuno-oncology targets in methylated compared with unmethylated IDH-wildtype glioblastoma ', Journal of Oncology, vol. 2021, 8819702 . https://doi.org/10.1155/2021/8819702

Introduction. Glioblastoma (GBM) is the most common primary adult brain tumour with a median overall survival (OS) of 12–15 months. Molecular characterization of multiple immunooncology targets in GBM may help target novel immunotherapeutic strateg

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https://europepmc.org/articles/PMC6789701/