Experience-dependent changes in hippocampal spatial activity and hippocampal circuit function are disrupted in a rat model of Fragile X Syndrome

Autor: Antonis Asiminas, Sam A. Booker, Owen R. Dando, Zrinko Kozic, Daisy Arkell, Felicity H. Inkpen, Anna Sumera, Irem Akyel, Peter C. Kind, Emma R. Wood

Publikováno v: Molecular Autism, Vol 13, Iss 1, Pp 1-29 (2022)

Abstract Background Fragile X syndrome (FXS) is a common single gene cause of intellectual disability and autism spectrum disorder. Cognitive inflexibility is one of the hallmarks of FXS with affected individuals showing extreme difficulty adapting t

Externí odkaz: https://doaj.org/article/e0dabc1eced84dd8ab6b7b80f7f03aae

SpAD Biofunctionalized Cellulose Acetate Scaffolds Inhibit Staphylococcus aureus Adherence in a Coordinating Function with the von Willebrand A1 Domain (vWF A1)

Autor: Stefanos Pendas, Antonis Asiminas, Alexandros Katranidis, Costas Tsioptsias, Maria Pitou, Georgios Papadopoulos, Theodora Choli-Papadopoulou

Publikováno v: Journal of Functional Biomaterials, Vol 13, Iss 1, p 21 (2022)

Staphylococcus aureus is one of the major pathogens causing and spreading hospital acquired infections. Since it is highly resistant to new generation antibiotics, novel strategies have to be developed such as the construction of biofunctionalized no

Externí odkaz: https://doaj.org/article/3035faec21484c6fb7442f5a529cb0fd

The continued need for animals to advance brain research

Autor: Paul J. Lucassen, Kate Jeffrey, Antonis Asiminas, Heidi M. B. Lesscher, Jos Prickaerts, Gertjan van Dijk, Amanda J. Kiliaan, Daniela Jezova, Carlos P. Fitzsimons, Klaus-Peter Lesch, S. Mechiel Korte, Ulrich L. M. Eisel, Roger A.H. Adan, Tamas Kozicz, Liset Menendez de la Prida, Joanes Grandjean, Marloes J. A. G. Henckens, Corette J. Wierenga, Vladyslav V. Vyazovskiy, Cyriel M. A. Pennartz, Marten P. Smidt, Ype Elgersma, Anne S. Mallien, Sharon M. Kolk, Liya Ma, Kirk Leech, Ingo Willuhn, Jorge F. Mejias, Maximilian Wiesmann, Frank J. Meye, Louk J. M. J. Vanderschuren, Marilise Escobar Burger, Sidarta Ribeiro, August B. Smit, Peter Meerlo, Robbert Havekes, Eddy A. van der Zee, Rixt van der Veen, Regien G. Schoemaker, Massimo Pasqualetti, Andries Kalsbeek, Martien J H Kas, Michael Bader, Joram D. Mul, Bernhard Englitz, Janine I. Rossato, Denovan P. Begg, Tomonori Takeuchi, Markus Wöhr, Antonio Fernández-Ruiz, Bella Williams, Nael Nadif Kasri, Aniko Korosi, Judith R. Homberg, Tom Beckers, Maarten Kamermans, Piotr Popik, Peter Gass, Umberto Olcese, Anna S. Mitchell, Christiane Herden, Jocelien D A Olivier, Monique Wolvekamp, Arjan Blokland, Azahara Oliva González, Natalia Alenina, Lisa Genzel, Wendy Jarrett, Ali-Akbar Salari, Roelof A. Hut, Anne-Marie van Dam, Anita Lüthi, Benno Roozendaal, Steven A. Kushner

Publikováno v: Neuron, 109(15), 2374-2379. Cell Press
Neuron, 109(15), 2374. Cell Press
Neuron, 109, 15, pp. 2374-2379
Neuron, 109, 2374-2379
Homberg, J R, Adan, R A H, Alenina, N, Asiminas, A, Bader, M, Beckers, T, Begg, D P, Blokland, A, Burger, M E, van Dijk, G, Eisel, U L M, Elgersma, Y, Englitz, B, Fernandez-Ruiz, A, Fitzsimons, C P, van Dam, A M, Gass, P, Grandjean, J, Havekes, R, Henckens, M J A G, Herden, C, Hut, R A, Jarrett, W, Jeffrey, K, Jezova, D, Kalsbeek, A, Kamermans, M, Kas, M J, Kasri, N N, Kiliaan, A J, Kolk, S M, Korosi, A, Korte, S M, Kozicz, T, Kushner, S A, Leech, K, Lesch, K P, Lesscher, H, Lucassen, P J, Luthi, A, Ma, L, Mallien, A S, Meerlo, P, Mejias, J F, Meye, F J, Mitchell, A S, Mul, J D, Olcese, U, González, A O, Olivier, J D A, Pasqualetti, M, Pennartz, C M A, Popik, P, Prickaerts, J, de la Prida, L M, Ribeiro, S, Roozendaal, B, Rossato, J I, Salari, A A, Schoemaker, R G, Smit, A B, Vanderschuren, L J M J, Takeuchi, T, van der Veen, R, Smidt, M P, Vyazovskiy, V V, Wiesmann, M, Wierenga, C J, Williams, B, Willuhn, I, Wöhr, M, Wolvekamp, M, van der Zee, E A & Genzel, L 2021, ' The continued need for animals to advance brain research ', Neuron, vol. 109, no. 15, pp. 2374-2379 . https://doi.org/10.1016/j.neuron.2021.07.015
Homberg, J R, Adan, R A H, Alenina, N, Asiminas, A, Bader, M, Beckers, T, Begg, D P, Blokland, A, Burger, M E, van Dijk, G, Eisel, U L M, Elgersma, Y, Englitz, B, Fernandez-Ruiz, A, Fitzsimons, C P, van Dam, A-M, Gass, P, Grandjean, J, Havekes, R, Henckens, M J A G, Herden, C, Hut, R A, Jarrett, W, Jeffrey, K, Jezova, D, Kalsbeek, A, Kamermans, M, Kas, M J, Kasri, N N, Kiliaan, A J, Kolk, S M, Korosi, A, Korte, S M, Kozicz, T, Kushner, S A, Leech, K, Lesch, K-P, Lesscher, H, Lucassen, P J, Luthi, A, Ma, L, Mallien, A S, Meerlo, P, Mejias, J F, Meye, F J, Mitchell, A S, Mul, J D, Olcese, U, González, A O, Olivier, J D A, Pasqualetti, M, Pennartz, C M A, Popik, P, Prickaerts, J, de la Prida, L M, Ribeiro, S, Roozendaal, B, Rossato, J I, Salari, A-A, Schoemaker, R G, Smit, A B, Vanderschuren, L J M J, Takeuchi, T, van der Veen, R, Smidt, M P, Vyazovskiy, V V, Wiesmann, M, Wierenga, C J, Williams, B, Willuhn, I, Wöhr, M, Wolvekamp, M, van der Zee, E A & Genzel, L 2021, ' The continued need for animals to advance brain research ', Neuron, vol. 109, no. 15, pp. 2374-2379 . https://doi.org/10.1016/j.neuron.2021.07.015
Neuron, 109(15), 2374-2379. CELL PRESS
Digital.CSIC. Repositorio Institucional del CSIC
instname

Policymakers aim to move toward animal-free alternatives for scientific research and have introduced very strict regulations for animal research. We argue that, for neuroscience research, until viable and translational alternatives become available a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2bfd05a12c81a1cd11d8bb8178a0953
https://doi.org/10.1016/j.neuron.2021.07.015

Liver-secreted fluorescent blood plasma markers enable chronic imaging of the microcirculation

Autor: Xiaowen Wang, Christine Delle, Antonis Asiminas, Sonam Akther, Marta Vittani, Peter Brøgger, Peter Kusk, Camilla Trang Vo, Tessa Radovanovic, Ayumu Konno, Hirokazu Hirai, Masahiro Fukuda, Pia Weikop, Steven A. Goldman, Maiken Nedergaard, Hajime Hirase

Publikováno v: Wang, X, Delle, C, Asiminas, A, Akther, S, Vittani, M, Brøgger, P, Kusk, P, Vo, C T, Radovanovic, T, Konno, A, Hirai, H, Fukuda, M, Weikop, P, Goldman, S A, Nedergaard, M & Hirase, H 2022, ' Liver-secreted fluorescent blood plasma markers enable chronic imaging of the microcirculation ', Cell Reports Methods, vol. 2, no. 10, 100302 . https://doi.org/10.1016/j.crmeth.2022.100302

Studying blood microcirculation is vital for gaining insights into vascular diseases. Blood flow imaging in deep tissue is currently achieved by acute administration of fluorescent dyes in the blood plasma. This is an invasive process, and the plasma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a6943bdb39e48b285ce5d2bf7791641
https://curis.ku.dk/ws/files/329745857/Fulltext.pdf

Review for 'Human wildtype tau expression in cholinergic pedunculopontine tegmental neurons is sufficient to produce PSP‐like behavioural deficits and neuropathology'

Autor: Antonis Asiminas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fe3ae7cf149e8d03246c9f8070f37b54
https://doi.org/10.1111/ejn.15496/v1/review1