Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Antonios Somarakis"'
Autor:
Christina Plattner, Giorgia Lamberti, Peter Blattmann, Alexander Kirchmair, Dietmar Rieder, Zuzana Loncova, Gregor Sturm, Stefan Scheidl, Marieke Ijsselsteijn, Georgios Fotakis, Asma Noureen, Rebecca Lisandrelli, Nina Böck, Niloofar Nemati, Anne Krogsdam, Sophia Daum, Francesca Finotello, Antonios Somarakis, Alexander Schäfer, Doris Wilflingseder, Miguel Gonzalez Acera, Dietmar Öfner, Lukas A. Huber, Hans Clevers, Christoph Becker, Henner F. Farin, Florian R. Greten, Ruedi Aebersold, Noel F.C.C. de Miranda, Zlatko Trajanoski
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108399- (2023)
Summary: Precision oncology approaches for patients with colorectal cancer (CRC) continue to lag behind other solid cancers. Functional precision oncology—a strategy that is based on perturbing primary tumor cells from cancer patients—could provi
Externí odkaz:
https://doaj.org/article/e7b86d875dee498688afb5b6da71b4a9
Autor:
Natasja Hendriks, Sjoerd H van der Burg, Ziena Abdulrahman, Noel F C C de Miranda, Edith M G van Esch, Peggy J de Vos van Steenwijk, Antonios Somarakis, Arnold J Kruse, Anna J M van de Sande, Heleen J van Beekhuizen, Jurgen M J Piek, Loes F S Kooreman, Brigitte F M Slangen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 11 (2022)
Background The complete response rate of cervical high-grade squamous intraepithelial lesion (cHSIL) patients to imiquimod immunotherapy is approximately 60%. Consequently, many patients are exposed to unnecessary adverse effects of imiquimod. On the
Externí odkaz:
https://doaj.org/article/ae2985823b1043c281f9a4695715eadb
Autor:
Boyd Kenkhuis, Antonios Somarakis, Lynn R.T. Kleindouwel, Willeke M.C. van Roon-Mom, Thomas Höllt, Louise van der Weerd
Publikováno v:
Neurobiology of Disease, Vol 167, Iss , Pp 105684- (2022)
Microglia have been identified as key players in Alzheimer's disease pathogenesis, and other neurodegenerative diseases. Iba1, and more specifically TMEM119 and P2RY12 are gaining ground as presumedly more specific microglia markers, but comprehensiv
Externí odkaz:
https://doaj.org/article/09aedfb13b844e219310394d2add8c36
Autor:
Boyd Kenkhuis, Antonios Somarakis, Lorraine de Haan, Oleh Dzyubachyk, Marieke E. IJsselsteijn, Noel F. C. C. de Miranda, Boudewijn P. F. Lelieveldt, Jouke Dijkstra, Willeke M. C. van Roon-Mom, Thomas Höllt, Louise van der Weerd
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-15 (2021)
Abstract Brain iron accumulation has been found to accelerate disease progression in amyloid-β(Aβ) positive Alzheimer patients, though the mechanism is still unknown. Microglia have been identified as key players in the disease pathogenesis, and ar
Externí odkaz:
https://doaj.org/article/3f4646cb0a074c658337fbd49da6c5aa
Autor:
Sjoerd H van der Burg, Thomas Höllt, Ziena Abdulrahman, Marieke E Ijsselsteijn, Noel F C C de Miranda, Dana A M Mustafa, Marij J P Welters, Zlatko Trajanoski, Saskia J Santegoets, Pornpimol Charoentong, Gregor Sturm, Antonios Somarakis, Francesca Finotello, Sylvia L van Egmond
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 2 (2022)
Externí odkaz:
https://doaj.org/article/f0029b590dda439cbaad7a04015bd7c8
Autor:
David Lähnemann, Johannes Köster, Ewa Szczurek, Davis J. McCarthy, Stephanie C. Hicks, Mark D. Robinson, Catalina A. Vallejos, Kieran R. Campbell, Niko Beerenwinkel, Ahmed Mahfouz, Luca Pinello, Pavel Skums, Alexandros Stamatakis, Camille Stephan-Otto Attolini, Samuel Aparicio, Jasmijn Baaijens, Marleen Balvert, Buys de Barbanson, Antonio Cappuccio, Giacomo Corleone, Bas E. Dutilh, Maria Florescu, Victor Guryev, Rens Holmer, Katharina Jahn, Thamar Jessurun Lobo, Emma M. Keizer, Indu Khatri, Szymon M. Kielbasa, Jan O. Korbel, Alexey M. Kozlov, Tzu-Hao Kuo, Boudewijn P.F. Lelieveldt, Ion I. Mandoiu, John C. Marioni, Tobias Marschall, Felix Mölder, Amir Niknejad, Alicja Rączkowska, Marcel Reinders, Jeroen de Ridder, Antoine-Emmanuel Saliba, Antonios Somarakis, Oliver Stegle, Fabian J. Theis, Huan Yang, Alex Zelikovsky, Alice C. McHardy, Benjamin J. Raphael, Sohrab P. Shah, Alexander Schönhuth
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-35 (2020)
Abstract The recent boom in microfluidics and combinatorial indexing strategies, combined with low sequencing costs, has empowered single-cell sequencing technology. Thousands—or even millions—of cells analyzed in a single experiment amount to a
Externí odkaz:
https://doaj.org/article/9368dc7f34b5489abc7fc8743d7a022d
Autor:
Saskia Santegoets, Thomas Höllt, Ziena Abdulrahman, Sjoerd van der Burg, Zlatko Trajanoski, Pornpimol Charoentong, Gregor Sturm, Marieke Ijsselsteijn, Antonios Somarakis, Francesca Finotello, Sylvia van Egmond, Dana Mustafa, Marij Welters, Noel de Miranda
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/bd2690d72df84212af7a10d67ce97f20
Autor:
Na Li, Vincent van Unen, Nannan Guo, Tamim Abdelaal, Antonios Somarakis, Jeroen Eggermont, Ahmed Mahfouz, Susana M. Chuva de Sousa Lopes, Boudewijn P. F. Lelieveldt, Frits Koning
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The human fetal immune system must protect the infant against the sudden exposure to a large variety of pathogens upon birth. While it is known that the fetal immune system develops in sequential waves, relatively little is known about the compositio
Externí odkaz:
https://doaj.org/article/a4176f1983424f9d88d52855430b0dbe
Autor:
Edith Van Esch, Ziena Abdulrahman, Natasja Hendriks, Arnold Jan Kruse, Antonios Somarakis, Anna Sande, Heleen Van Beekhuizen, Jurgen Piek, Noel De Miranda, Loes Kooreman, Brigitte Slangen, Sjoerd Van Der Burg, Peggy De Vos Van Steenwijk
Publikováno v:
E-Posters.
Autor:
Ziena Abdulrahman, Natasja Hendriks, Arnold J Kruse, Antonios Somarakis, Anna J M van de Sande, Heleen J van Beekhuizen, Jurgen M J Piek, Noel F C C de Miranda, Loes F S Kooreman, Brigitte F M Slangen, Sjoerd H van der Burg, Peggy J de Vos van Steenwijk, Edith M G van Esch
Publikováno v:
Journal for ImmunoTherapy of Cancer, 10(11). BMJ PUBLISHING GROUP
Journal for ImmunoTherapy of Cancer, 10(11):e005288. BioMed Central Ltd
Journal for ImmunoTherapy of Cancer, 10(11):e005288. BioMed Central Ltd.
Journal for ImmunoTherapy of Cancer, 10(11):e005288. BioMed Central Ltd
Journal for ImmunoTherapy of Cancer, 10(11):e005288. BioMed Central Ltd.
BackgroundThe complete response rate of cervical high-grade squamous intraepithelial lesion (cHSIL) patients to imiquimod immunotherapy is approximately 60%. Consequently, many patients are exposed to unnecessary adverse effects of imiquimod. On the