Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Antonios Dougalis"'
Autor:
Nadja Mannal, Katharina Kleiner, Michael Fauler, Antonios Dougalis, Christina Poetschke, Birgit Liss
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 13 (2021)
Dopaminergic (DA) midbrain neurons within the substantia nigra (SN) display an autonomous pacemaker activity that is crucial for dopamine release and voluntary movement control. Their progressive degeneration is a hallmark of Parkinson's disease. The
Externí odkaz:
https://doaj.org/article/c71a5a5bc85741aa9ab9e5f31a80507f
Autor:
Anssi Pelkonen, Cristiana Pistono, Pamela Klecki, Mireia Gómez-Budia, Antonios Dougalis, Henna Konttinen, Iveta Stanová, Ilkka Fagerlund, Ville Leinonen, Paula Korhonen, Tarja Malm
Publikováno v:
Cells, Vol 11, Iss 1, p 106 (2021)
Human pluripotent stem cell (hPSC)-derived neuron cultures have emerged as models of electrical activity in the human brain. Microelectrode arrays (MEAs) measure changes in the extracellular electric potential of cell cultures or tissues and enable t
Externí odkaz:
https://doaj.org/article/7de37164e56a4d1bb687d636042e7579
Autor:
Ilkka Fagerlund, Antonios Dougalis, Anastasia Shakirzyanova, Mireia Gómez-Budia, Anssi Pelkonen, Henna Konttinen, Sohvi Ohtonen, Mohammad Feroze Fazaludeen, Marja Koskuvi, Johanna Kuusisto, Damián Hernández, Alice Pebay, Jari Koistinaho, Tuomas Rauramaa, Šárka Lehtonen, Paula Korhonen, Tarja Malm
Publikováno v:
Cells, Vol 11, Iss 1, p 124 (2021)
Human cerebral organoids, derived from induced pluripotent stem cells, offer a unique in vitro research window to the development of the cerebral cortex. However, a key player in the developing brain, the microglia, do not natively emerge in cerebral
Externí odkaz:
https://doaj.org/article/51d43edc458d422caf349e2f8da0e316
Autor:
Malm, Ilkka Fagerlund, Antonios Dougalis, Anastasia Shakirzyanova, Mireia Gómez-Budia, Anssi Pelkonen, Henna Konttinen, Sohvi Ohtonen, Mohammad Feroze Fazaludeen, Marja Koskuvi, Johanna Kuusisto, Damián Hernández, Alice Pebay, Jari Koistinaho, Tuomas Rauramaa, Šárka Lehtonen, Paula Korhonen, Tarja
Publikováno v:
Cells; Volume 11; Issue 1; Pages: 124
Human cerebral organoids, derived from induced pluripotent stem cells, offer a unique in vitro research window to the development of the cerebral cortex. However, a key player in the developing brain, the microglia, do not natively emerge in cerebral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::53a42de8b82df44f6960f875d28a43c7
Autor:
Jari Koistinaho, Mireia Gomez-Budia, Sohvi Ohtonen, Alice Pébay, Johanna Kuusisto, Ilkka Fagerlund, Anastasia Shakirzyanova, Henna Konttinen, Antonios Dougalis, Šárka Lehtonen, Damián Hernández, Feroze Fazaludeen, Marja Koskuvi, Paula Korhonen, Tarja Malm
Publikováno v:
SSRN Electronic Journal.
Human stem cell-derived brain organoids provide a physiologically relevant in vitro 3D brain model for studies of neurological development that are unique to the human nervous system. Prior studies have reported protocols that support the maturation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a25f3275508d28b5b8f92404356a1d2a
https://doi.org/10.2139/ssrn.3773789
https://doi.org/10.2139/ssrn.3773789
Autor:
Mireia Gomez-Budia, Henna Konttinen, Ilkka Fagerlund, Sohvi Ohtonen, Jari Koistinaho, Anastasia Shakirzyanova, Šárka Lehtonen, Paula Korhonen, Marja Koskuvi, Feroze Fazaludeen, Alice Pébay, Tarja Malm, Antonios Dougalis, Damián Hernández, Johanna Kuusisto
Human stem cell-derived brain organoids provide a physiologically relevant in vitro 3D brain model for studies of neurological development that are unique to the human nervous system. Prior studies have reported protocols that support the maturation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf5d441cd87a9ef6c5ab5e6884eb91d0
https://doi.org/10.1101/2020.12.08.416388
https://doi.org/10.1101/2020.12.08.416388
Autor:
Nadja, Mannal, Katharina, Kleiner, Michael, Fauler, Antonios, Dougalis, Christina, Poetschke, Birgit, Liss
Publikováno v:
Frontiers in Synaptic Neuroscience
Dopaminergic (DA) midbrain neurons within the substantia nigra (SN) display an autonomous pacemaker activity that is crucial for dopamine release and voluntary movement control. Their progressive degeneration is a hallmark of Parkinson's disease. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6694b1e78448abeaca45f8bc967a2b94
https://pubmed.ncbi.nlm.nih.gov/33716704
https://pubmed.ncbi.nlm.nih.gov/33716704
Autor:
Maria Kharitonova, Simon Hess, Birgit Liss, Petronel Tuluc, Nadia Stefanova, Thomas Pomberger, Antonios Dougalis, Peter Kloppenburg, Nadine J. Ortner, Florian Pitterl, Herbert Oberacher, Joerg Striessnig, Gabriella Bock, Thomas Ciossek, Henning J. Draheim, Johanna Duda
Publikováno v:
The Journal of Neuroscience. 37:6761-6777
Ca(2+)-influx through L-type Ca(2+)-channels (LTCCs) is associated with activity-related stressful oscillations of Ca(2+) levels within dopaminergic (DA) neurons in the substantia nigra (SN), which may contribute to their selective degeneration in Pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27e2399435dc953e2bd3b59303305375
https://doi.org/10.1523/jneurosci.2946-16.2017
https://doi.org/10.1523/jneurosci.2946-16.2017
Autor:
Antonios Dougalis, Gillian A. Matthews, Kazuto Kobayashi, Frédéric Brischoux, Matthew W. Bishop, Mark A. Ungless
Publikováno v:
European Journal of Neuroscience. 36:3322-3332
The dorsal raphe nucleus (DRN) and ventrolateral periaqueductal grey (vlPAG) regions contain populations of dopamine neurons, often considered to be a dorsal caudal extension of the A10 group [mostly found in the ventral tegmental area (VTA)]. Recent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::759de4091375e46f0aebcdffbcca0aef
https://doi.org/10.1111/j.1460-9568.2012.08255.x
https://doi.org/10.1111/j.1460-9568.2012.08255.x
Autor:
Mark A. Ungless, Matthew W. Bishop, Antonios Dougalis, Richard Festenstein, Nicholas W. Wood, Gillian A. Matthews, Subhojit Chakraborty
Publikováno v:
Journal of Neurophysiology. 104:3009-3020
The electrophysiological properties of substantia nigra pars compacta (SNC) dopamine neurons can influence their susceptibility to degeneration in toxin-based models of Parkinson's disease (PD), suggesting that excitotoxic and/or hypoactive mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bbdc936176d8d2545019ef647023076
https://doi.org/10.1152/jn.00466.2010
https://doi.org/10.1152/jn.00466.2010