Zobrazeno 1 - 10
of 195
pro vyhledávání: '"Antonio di Stefano"'
Autor:
Aikaterini Katsogiannou, Danai Karta, Antonio Di Stefano, Sena Oner, Mehmet Enes Arslan, Adil Mardinoglu, Hasan Turkez, Stamatia Vassiliou, Ivana Cacciatore
Publikováno v:
European Journal of Medicinal Chemistry Reports, Vol 12, Iss , Pp 100235- (2024)
In the field of medicinal chemistry, the versatility of the thiosemicarbazone scaffold makes it a promising platform for the development of next-generation pharmaceuticals. In this paper the thiosemicarbazone scaffold was explored to obtain novel ser
Externí odkaz:
https://doaj.org/article/af0c1553b91e47a89af91e235b05e0b5
Autor:
Annalisa Di Rienzo, Lisa Marinelli, Marilisa Pia Dimmito, Eleonora Chiara Toto, Antonio Di Stefano, Ivana Cacciatore
Publikováno v:
Pharmaceutics, Vol 16, Iss 9, p 1185 (2024)
Inflammatory bowel disease (IBD) is a chronic gastrointestinal inflammatory disorder with two main subtypes: ulcerative colitis (UC) and Crohn’s disease (CD). The pathogenesis involves genetic predisposition, dysbiosis, and immune dysregulation. Co
Externí odkaz:
https://doaj.org/article/d38388c86bd5453f9bbe86d933738547
Autor:
Antonio Maria Leone, Stefano Migliaro, Giuseppe Zimbardo, Pio Cialdella, Eloisa Basile, Domenico Galante, Federico Di Giusto, Gianluca Anastasia, Andrea Vicere, Edoardo Petrolati, Antonio Di Stefano, Giorgia Campaniello, Domenico D’Amario, Rocco Vergallo, Rocco Antonio Montone, Antonino Buffon, Enrico Romagnoli, Cristina Aurigemma, Francesco Burzotta, Carlo Trani, Filippo Crea
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundWhile the importance of invasive physiological assessment (IPA) to choose coronary lesions to be treated is ascertained, its role after PCI is less established. We evaluated feasibility and efficacy of Physiology-guided PCI in the everyday
Externí odkaz:
https://doaj.org/article/8d303e62d9954cd4bec1a70cc5e412df
Autor:
Hasan Turkez, Ozlem Ozdemir Tozlu, Arzu Tatar, Mehmet Enes Arslan, Kenan Cadirci, Lisa Marinelli, Omer Erkan Yapca, Ivana Cacciatore, Antonio Di Stefano, Adil Mardinoglu
Publikováno v:
Journal of Toxicology, Vol 2022 (2022)
The tripeptide H-Gly-Pro-Glu-OH (GPE) and its analogs began to take much interest from scientists for developing effective novel molecules in the treatment of several disorders including Alzheimer’s disease, Parkinson’s disease, and stroke. The p
Externí odkaz:
https://doaj.org/article/b535917013fb4dc486033b510d93eda1
Autor:
Ivana Cacciatore, Sonia Spalletta, Annalisa Di Rienzo, Vincenzo Flati, Erika Fornasari, Laura Pierdomenico, Piero Del Boccio, Silvia Valentinuzzi, Erica Costantini, Elena Toniato, Stefano Martinotti, Carmela Conte, Antonio Di Stefano, Iole Robuffo
Publikováno v:
Pharmaceuticals, Vol 16, Iss 3, p 340 (2023)
(1) Background: Obesity, a complex metabolic disease resulting from an imbalance between food consumption and energy expenditure, leads to an increase in adipocytes and chronic inflammatory conditions. The aim of this paper was to synthesize a small
Externí odkaz:
https://doaj.org/article/cf678bff4bc14b73ac2165405fd2fc1c
Autor:
Lise Secardin, Cintia Gomez Limia, Suzana da Silva-Benedito, Larissa Lordier, Mira El-Khoury, Caroline Marty, Jean-Christophe Ianotto, Hana Raslova, Stefan N. Constantinescu, Martín Hernán Bonamino, William Vainchenker, Barbara Monte-Mor, Antonio Di Stefano, Isabelle Plo
Publikováno v:
HemaSphere, Vol 5, Iss 7, p e593 (2021)
Mutations in the calreticulin (CALR) gene are seen in about 30% of essential thrombocythemia and primary myelofibrosis patients. To address the contribution of the human CALR mutants to the pathogenesis of myeloproliferative neoplasms (MPNs) in an en
Externí odkaz:
https://doaj.org/article/ed03a7d29143423c88ba281faecea3bf
Autor:
Lisa Marinelli, Michele Ciulla, Jeffrey A. S. Ritsema, Cornelus F. van Nostrum, Ivana Cacciatore, Marilisa Pia Dimmito, Ferdinando Palmerio, Giustino Orlando, Iole Robuffo, Rossella Grande, Valentina Puca, Antonio Di Stefano
Publikováno v:
Pharmaceutics, Vol 14, Iss 9, p 1821 (2022)
The encapsulation of peptides and proteins in nanosystems has been extensively investigated for masking unfavorable biopharmaceutical properties, including short half-life and poor permeation through biological membranes. Therefore, the aim of this w
Externí odkaz:
https://doaj.org/article/53ac679e448c4c68b40b1f0df8ec6e9e
Autor:
Nursah Aydin, Hasan Turkez, Ozlem Ozdemir Tozlu, Mehmet Enes Arslan, Mehmet Yavuz, Erdal Sonmez, Ozgur Fırat Ozpolat, Ivana Cacciatore, Antonio Di Stefano, Adil Mardinoglu
Publikováno v:
Nanomaterials, Vol 12, Iss 15, p 2690 (2022)
Alzheimer’s disease (AD) is considered as the most common neurodegenerative disease. Extracellular amyloid beta (Aβ) deposition is a hallmark of AD. The options based on degradation and clearance of Aβ are preferred as promising therapeutic strat
Externí odkaz:
https://doaj.org/article/4ac967ef648c4ac28be3bca492e1b4d2
Autor:
Lisa Marinelli, Ivana Cacciatore, Erica Costantini, Marilisa Pia Dimmito, Federica Serra, Antonio Di Stefano, Marcella Reale
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1468 (2022)
Background. Wound healing (WH) is a complex process involving several stages, such as hemostasis, inflammation, re-epithelialization, and remodeling. Many factors can impair WH, and different pharmacological approaches were studied to date, but the i
Externí odkaz:
https://doaj.org/article/5f6321b5f6324fb7960f6bd85fac7e81
Autor:
Lise Secardin, Cintia Elisabeth Gomez Limia, Antonio di Stefano, Martin Hernan Bonamino, Joseph Saliba, Keisuke Kataoka, Stevens K. Rehen, Hana Raslova, Caroline Marty, Seishi Ogawa, William Vainchenker, Barbara da Costa Reis Monte-Mor, Isabelle Plo
Publikováno v:
Stem Cell Research, Vol 44, Iss , Pp - (2020)
The discovery of the Ten-Eleven Translocation (TET) protein family was initiated by the identification of the MLL partner TET1, and of mutations in the TET2 gene in hematological malignancies including myeloproliferative neoplasms (MPN). TET1, 2 and
Externí odkaz:
https://doaj.org/article/fda6ae5400dc4a7788bc2821b7224116