Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Antonio Zandona"'
Autor:
Suzana Žunec, Donna Vadlja, Alma Ramić, Antonio Zandona, Nikola Maraković, Iva Brekalo, Ines Primožič, Maja Katalinić
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 155 (2023)
The cholinergic system, relying on the neurotransmitter acetylcholine (ACh), plays a significant role in muscle contraction, cognition, and autonomic nervous system regulation. The enzymes acetylcholinesterase, AChE, and butyrylcholinesterase, BChE,
Externí odkaz:
https://doaj.org/article/29fc6c3e225e4e27a88c3311bcaa3b8b
Autor:
Dajana Gašo Sokač, Antonio Zandona, Sunčica Roca, Dražen Vikić-Topić, Gabriela Lihtar, Nikola Maraković, Valentina Bušić, Zrinka Kovarik, Maja Katalinić
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13388 (2022)
Seven pyridoxal dioxime quaternary salts (1–7) were synthesized with the aim of studying their interactions with human acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). The synthesis was achieved by the quaternization of pyridoxal monoo
Externí odkaz:
https://doaj.org/article/5f2c90793be44509bd90d5541541ff6e
Autor:
Ana Matošević, Anamarija Knežević, Antonio Zandona, Nikola Maraković, Zrinka Kovarik, Anita Bosak
Publikováno v:
Pharmaceuticals, Vol 15, Iss 10, p 1220 (2022)
As butyrylcholinesterase (BChE) plays a role in the progression of symptoms and pathophysiology of Alzheimer’s disease (AD), selective inhibition of BChE over acetylcholinesterase (AChE) can represent a promising pathway in treating AD. The carbama
Externí odkaz:
https://doaj.org/article/a7963318431d4bbd97d70547ea52cf14
Autor:
Anamarija Štafa, Bojan Žunar, Andrea Pranklin, Antonio Zandona, Marina Svetec Miklenić, Božidar Šantek, Ivan Krešimir Svetec
Publikováno v:
Food Technology and Biotechnology, Vol 57, Iss 1, Pp 5-16 (2019)
Bioethanol production from lignocellulosic hydrolysates requires a producer strain that tolerates both the presence of growth and fermentation inhibitors and high ethanol concentrations. Therefore, we constructed heterozygous intraspecies hybrid dipl
Externí odkaz:
https://doaj.org/article/6ccc7197905245de84f2cfbfe5aa71ba
Publikováno v:
Toxics, Vol 10, Iss 2, p 97 (2022)
The toxicity of eight polybrominated diphenyl ethers (PBDEs) congeners detected in environmental and biological samples (BDE-28, -47, -99, -100, -153, -154, -183, and -209) was evaluated on the epithelial lung cells. Exposure to these PBDEs increased
Externí odkaz:
https://doaj.org/article/7649d18651354381a69898021e0bfcc4
Autor:
Ana Matošević, Andreja Radman Kastelic, Ana Mikelić, Antonio Zandona, Maja Katalinić, Ines Primožič, Anita Bosak, Tomica Hrenar
Publikováno v:
Pharmaceutics, Vol 13, Iss 3, p 420 (2021)
The treatment of central nervous system (CNS) diseases related to the decrease of neurotransmitter acetylcholine in neurons is based on compounds that prevent or disrupt the action of acetylcholinesterase and butyrylcholinesterase. A series of thirte
Externí odkaz:
https://doaj.org/article/a3342646a5eb4a7dbcbfc8787df0e4be
Autor:
Antonio Zandona, Gabriela Lihtar, Nikola Maraković, Katarina Miš, Valentina Bušić, Dajana Gašo-Sokač, Sergej Pirkmajer, Maja Katalinić
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 8088 (2020)
We evaluated the potential of nine vitamin B3 scaffold-based derivatives as acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitors, as a starting point for the development of novel drugs for treating disorders with cholinergic neurot
Externí odkaz:
https://doaj.org/article/9b7b5420f90a463ca9d8b4b7c889424b
Publikováno v:
Molecules, Vol 22, Iss 7, p 1234 (2017)
For the last six decades, researchers have been focused on finding efficient reactivators of organophosphorus compound (OP)-inhibited acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). In this study, we have focused our research on a new o
Externí odkaz:
https://doaj.org/article/2bba7117d34c4817865dee2ce0d82c1a
Autor:
Vesna Pehar, Dora Kolić, Antonio Zandona, Goran Šinko, Maja Katalinić, Višnja Stepanić, Zrinka Kovarik
Publikováno v:
Chemico-Biological Interactions. 379:110506
Sets of 346 herbicides in use and 163 no longer in use were collected from open access online sources and compared in silico with cholinesterases inhibitors (ChI) and drugs in terms of physicochemical profile and estimated toxic effects on human heal
Autor:
Antonio Zandona, Maja Katalinić
Publikováno v:
Periodicum biologorum
Volume 121-122
Issue 3-4
Volume 121-122
Issue 3-4
The communication between the nervous and other systems in the organism is carried out by the transmission of nerve impulses. Diverse neurotransmitters are released into the synaptic cleft and bind to the specific receptors at the neighbouring cell t