Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Antonio Sica"'
Autor:
Francesca Maria Consonni, Barbara Durante, Marcello Manfredi, Augusto Bleve, Chiara Pandolfo, Valentina Garlatti, Virginia Vita Vanella, Emilio Marengo, Elettra Barberis, Barbara Bottazzi, Sara Bombace, Ilaria My, Gianluigi Condorelli, Valter Torri, Antonio Sica
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Even though cancer patients are generally considered more susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the mechanisms driving their predisposition to severe forms of coronavirus disease 2019 (COVID-19) have n
Externí odkaz:
https://doaj.org/article/cd79b754e270428c80b3122a228e5e7b
Autor:
Elettra Barberis, Shahzaib Khoso, Antonio Sica, Marco Falasca, Alessandra Gennari, Francesco Dondero, Antreas Afantitis, Marcello Manfredi
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11269 (2022)
Recent technological innovations in the field of mass spectrometry have supported the use of metabolomics analysis for precision medicine. This growth has been allowed also by the application of algorithms to data analysis, including multivariate and
Externí odkaz:
https://doaj.org/article/2c5521b9c2fc4ea99f780206f833f0b9
Publikováno v:
Cell Stress, Vol 3, Iss 9, Pp 284-294 (2019)
Cancers promote immunological stresses that induce alterations of the myelopoietic output, defined as emergency myelopoiesis, which lead to the generation of different myeloid populations endowed with tumor-promoting activities. New evidence indicate
Externí odkaz:
https://doaj.org/article/8173b8873f1d4803a51594bb787da34f
Autor:
Elettra Barberis, Virginia V. Vanella, Marco Falasca, Valeria Caneapero, Giuseppe Cappellano, Davide Raineri, Marco Ghirimoldi, Veronica De Giorgis, Chiara Puricelli, Rosanna Vaschetto, Pier Paolo Sainaghi, Stefania Bruno, Antonio Sica, Umberto Dianzani, Roberta Rolla, Annalisa Chiocchetti, Vincenzo Cantaluppi, Gianluca Baldanzi, Emilio Marengo, Marcello Manfredi
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Knowledge of the host response to the novel coronavirus SARS-CoV-2 remains limited, hindering the understanding of COVID-19 pathogenesis and the development of therapeutic strategies. During the course of a viral infection, host cells release exosome
Externí odkaz:
https://doaj.org/article/5c8152a875d94a0eac37e5448b8b9f15
Autor:
Fabrizio Antonangeli, Ambra Natalini, Marina Chiara Garassino, Antonio Sica, Angela Santoni, Francesca Di Rosa
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Immune checkpoints are inhibitory receptor/ligand pairs regulating immunity that are exploited as key targets of anti-cancer therapy. Although the PD-1/PD-L1 pair is one of the most studied immune checkpoints, several aspects of its biology remain to
Externí odkaz:
https://doaj.org/article/f04d516e15fd43b4b7d66ae7ea8db14f
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Frailty is a syndrome characterized by the decline in the physiologic reserve and function of several systems, leading to increased vulnerability and adverse health outcomes. While common in the elderly, recent studies have underlined the higher prev
Externí odkaz:
https://doaj.org/article/2ef963cb1d1049e399ac1130c60159d3
Autor:
Antonio Sica, Marta Di Martile, Valentina Farini, Francesca Maria Consonni, Daniela Trisciuoglio, Marianna Desideri, Elisabetta Valentini, Simona D'Aguanno, Maria Grazia Tupone, Simonetta Buglioni, Cristiana Ercolani, Enzo Gallo, Bruno Amadio, Irene Terrenato, Maria Laura Foddai, Donatella Del Bufalo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
BackgroundA bidirectional crosstalk between tumor cells and the surrounding microenvironment contributes to tumor progression and response to therapy. Our previous studies have demonstrated that bcl-2 affects melanoma progression and regulates the tu
Externí odkaz:
https://doaj.org/article/0961c635f0ff4438ae7ac8440e0572b5
Publikováno v:
Cancers, Vol 14, Iss 3, p 510 (2022)
In recent years, the immune system has emerged as a critical regulator of tumor development, progression and dissemination. Advanced therapeutic approaches targeting immune cells are currently under clinical use and improvement for the treatment of p
Externí odkaz:
https://doaj.org/article/99d5c1402c8640b0aa81679b73d120c8
Autor:
Sabina Sangaletti, Giovanna Talarico, Claudia Chiodoni, Barbara Cappetti, Laura Botti, Paola Portararo, Alessandro Gulino, Francesca Maria Consonni, Antonio Sica, Giovanni Randon, Massimo Di Nicola, Claudio Tripodo, Mario P. Colombo
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Myeloid-derived suppressor cells (MDSC) are well-known key negative regulators of the immune response during tumor growth, however scattered is the knowledge of their capacity to influence and adapt to the different tumor microenvironments and of the
Externí odkaz:
https://doaj.org/article/0713315082ce404b85fa8656bc18887e
Autor:
Francesca Maria Consonni, Chiara Porta, Arianna Marino, Chiara Pandolfo, Silvia Mola, Augusto Bleve, Antonio Sica
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Myeloid-derived suppressor cells (MDSCs) represent a heterogeneous population of immature myeloid cells with major regulatory functions and rise during pathological conditions, including cancer, infections and autoimmune conditions. MDSC expansion is
Externí odkaz:
https://doaj.org/article/0ee969d39d2447d190527f35dc5640aa