Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Antonio R. Pombinho"'
Autor:
Vladimir Korinek, Petr Bartunek, Zbynek Zdrahal, Jindrich Jindrich, Olga Machonova, Vitezslav Kriz, Monika Horazna, Eva Sloncova, Michaela Krausova, Dietmar Gradl, Jitka Stancikova, Martina Vojtechova, Antonio R. Pombinho, Lucie Tumova
PDF file - 515KB, Supplementary Materials and Methods. Supplementary Figure S1. Densitometric analysis of western blots shown in Figs. 2D (A), 3C (B) and 4D (C). Supplementary Figure S2. Monensin suppresses Wnt signaling activated by TALEN-induced di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8711be6e574a82a73568181fdd1f47d
https://doi.org/10.1158/1535-7163.22499776.v1
https://doi.org/10.1158/1535-7163.22499776.v1
Autor:
Vladimir Korinek, Petr Bartunek, Zbynek Zdrahal, Jindrich Jindrich, Olga Machonova, Vitezslav Kriz, Monika Horazna, Eva Sloncova, Michaela Krausova, Dietmar Gradl, Jitka Stancikova, Martina Vojtechova, Antonio R. Pombinho, Lucie Tumova
The Wnt signaling pathway is required during embryonic development and for the maintenance of homeostasis in adult tissues. However, aberrant activation of the pathway is implicated in a number of human disorders, including cancer of the gastrointest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0b5ad80d390450cfcc66779c4db350e
https://doi.org/10.1158/1535-7163.c.6536254
https://doi.org/10.1158/1535-7163.c.6536254
Publikováno v:
Molecules
Volume 24
Issue 11
Molecules, Vol 24, Iss 11, p 2152 (2019)
Volume 24
Issue 11
Molecules, Vol 24, Iss 11, p 2152 (2019)
Tumor suppressor p53 is mutated in about 50% of cancers. Most malignant melanomas carry wild-type p53, but p53 activity is often inhibited due to overexpression of its negative regulators Mdm2 or MdmX. We performed high throughput screening of 2448 c
Publikováno v:
BioMed Research International, Vol 2017 (2017)
Leishmaniasis is an infectious disease caused by protozoan parasites of the genusLeishmania. There is no vaccine against human leishmaniasis and the treatment of the disease would benefit from a broader spectrum and a higher efficacy of leishmanicida
Autor:
Kamila Benkova, Jan Mestak, Eva Matoušková, Ondrej Mestak, Zuzana Spurkova, Martin Molitor, Antonio R. Pombinho, Pavel Vesely, Andrej Sukop
Publikováno v:
Artificial Organs. 38:572-579
Biological meshes are biomaterials consisting of extracellular matrix that are used in surgery particularly for hernia treatment, thoracic wall reconstruction, or silicone implant-based breast reconstruction. We hypothesized that combination of extra
Autor:
Ladislav Andera, Pavel Klener, Jan Molinsky, Magdalena Klanova, Petr Bartunek, Antonio R. Pombinho, Michal Koc, Jarmila Spegarova, Lenka Beranova
Publikováno v:
Apoptosis. 18:739-750
TNF-related apoptosis-inducing ligand (TRAIL) is a pro-apoptotic ligand from the TNF-alpha family that is under consideration, along with agonistic anti-TRAIL receptor antibodies, as a potential anti-tumor agent. However, most primary human tumors ar
Autor:
Petr Bartůněk, Kateřina Bogdanová, Otakar Nyc, Radek Pohl, Milan Kolář, Eva Zborníková, Soňa Kovačková, Antonio R. Pombinho, Alžbeta Rabatinová, Libor Krásný, Hana Šanderová, Dominik Rejman, Tomáš Látal
Publikováno v:
Journal of Medicinal Chemistry. 54:7884-7898
Novel compounds termed lipophosphonoxins were prepared using a simple and efficient synthetic approach. The general structure of lipophosphonoxins consists of four modules: (i) a nucleoside module, (ii) an iminosugar module, (iii) a hydrophobic modul
Autor:
Zbyněk Kozmik, Čestmír Vlček, Jan Pačes, Peter Fabian, Michaela Liegertová, Jiří Pergner, Hynek Strnad, Petr Bartůněk, Iryna Kozmikova, Antonio R. Pombinho
Publikováno v:
Scientific Reports
Animals sense light primarily by an opsin-based photopigment present in a photoreceptor cell. Cnidaria are arguably the most basal phylum containing a well-developed visual system. The evolutionary history of opsins in the animal kingdom has not yet
Autor:
Jan Pačes, Peter Fabian, Michaela Liegertová, Petr Bartůněk, Iryna Kozmikova, Jiří Pergner, Hynek Strnad, Antonio R. Pombinho, Čestmír Vlček, Zbyněk Kozmik
Publikováno v:
Scientific Reports
Animals sense light primarily by an opsin-based photopigment present in a photoreceptor cell. Cnidaria are arguably the most basal phylum containing a well-developed visual system. The evolutionary history of opsins in the animal kingdom has not yet
Autor:
Petr Bartunek, Vitezslav Kriz, Jindrich Jindrich, Martina Vojtechova, Eva Sloncova, Antonio R. Pombinho, Dietmar Gradl, Jitka Stancikova, Lucie Tumova, Vladimir Korinek, Michaela Krausova, Olga Machonova, Zbynek Zdrahal, Monika Horazna
Publikováno v:
Molecular cancer therapeutics. 13(4)
The Wnt signaling pathway is required during embryonic development and for the maintenance of homeostasis in adult tissues. However, aberrant activation of the pathway is implicated in a number of human disorders, including cancer of the gastrointest