Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Antonio Porcellini"'
Autor:
Maria Teresa Lepore, Sara Bruzzaniti, Claudia La Rocca, Clorinda Fusco, Fortunata Carbone, Maria Mottola, Bruno Zuccarelli, Roberta Lanzillo, Vincenzo Brescia Morra, Giorgia Teresa Maniscalco, Salvatore De Simone, Claudio Procaccini, Antonio Porcellini, Veronica De Rosa, Mario Galgani, Silvana Cassano, Giuseppe Matarese
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The molecular mechanisms that govern differential T cell development from CD4+CD25-conventional T (Tconv) into CD4+CD25+ forkhead-box-P3+ (FoxP3+) inducible regulatory T (iTreg) cells remain unclear. Herein, we investigated the relative cont
Externí odkaz:
https://doaj.org/article/4e9e2b02aff64effb4aeec4badc1418f
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background KRAS is the undisputed champion of oncogenes, and despite its prominent role in oncogenesis as mutated gene, KRAS mutation appears infrequent in gliomas. Nevertheless, gliomas are considered KRAS-driven cancers due to its essentia
Externí odkaz:
https://doaj.org/article/5099db937db847698c933736f1c241e8
Autor:
Michele Rinaldi, Antonio Pezone, Gaia Italia Quadrini, Gianmarco Abbadessa, Maria Paola Laezza, Maria Laura Passaro, Antonio Porcellini, Ciro Costagliola
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
The intricate parallels in structure and function between the human retina and the central nervous system designate the retina as a prospective avenue for understanding brain-related processes. This review extensively explores the shared physiopathol
Externí odkaz:
https://doaj.org/article/7915aceac267461d9ece038f82e44e06
Publikováno v:
Redox Report, Vol 27, Iss 1, Pp 150-157 (2022)
Background Although the protooncogenes small GTPases Ras are redox-sensitive proteins, how they are regulated by redox signaling in the central nervous system (CNS) is still poorly understood. Alteration in redox-sensitive targets by redox signaling
Externí odkaz:
https://doaj.org/article/873510f4b9b843bb84e109b8ce2e5609
Autor:
Teresa Improda, Valentina Morgera, Maria Vitale, Lorenzo Chiariotti, Fabiana Passaro, Antonia Feola, Antonio Porcellini, Mariella Cuomo, Antonio Pezone
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 9951 (2023)
Cell identity is determined by the chromatin structure and profiles of gene expression, which are dependent on chromatin accessibility and DNA methylation of the regions critical for gene expression, such as enhancers and promoters. These epigenetic
Externí odkaz:
https://doaj.org/article/d25ae182487e4d2e9da2cd82607c95d0
Autor:
Alberto Angrisani, Nunzia Matrone, Valentina Belli, Rosario Vicidomini, Nunzia Di Maio, Mimmo Turano, Filippo Scialò, Paolo Antonio Netti, Antonio Porcellini, Maria Furia
Publikováno v:
Redox Biology, Vol 14, Iss , Pp 557-565 (2018)
The human DKC1 gene encodes dyskerin, an evolutionarily conserved nuclear protein whose overexpression represents a common trait of many types of aggressive sporadic cancers. As a crucial component of the nuclear H/ACA snoRNP complexes, dyskerin is i
Externí odkaz:
https://doaj.org/article/b6b394d1881f435cad3630f3b4141ba9
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/fb457870c4524745b326bb16b2459646
Autor:
Antonella Romano, Antonia Feola, Antonio Porcellini, Vincenzo Gigantino, Maurizio Di Bonito, Annabella Di Mauro, Rocco Caggiano, Raffaella Faraonio, Candida Zuchegna
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 17, p 5989 (2020)
The estrogen receptor (ER) signaling regulates numerous physiological processes mainly through activation of gene transcription (genomic pathways). Caveolin1 (CAV1) is a membrane-resident protein that behaves as platform to enable different signaling
Externí odkaz:
https://doaj.org/article/4f130e67aae645da83e11d14e6cc1429
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Adult neurogenesis is widespread among metazoans, it occurs in animals with a network nervous system, as cnidarians, and in animals with a complex and centralized brain, such as mammals, non-mammalian vertebrates, ecdysozoans, and a lophotrochozoan,
Externí odkaz:
https://doaj.org/article/3341d56b55b243d0946f58a05e122808
Autor:
Concetta Cuozzo, Antonio Porcellini, Tiziana Angrisano, Annalisa Morano, Bongyong Lee, Alba Di Pardo, Samantha Messina, Rodolfo Iuliano, Alfredo Fusco, Maria R Santillo, Mark T Muller, Lorenzo Chiariotti, Max E Gottesman, Enrico V Avvedimento
Publikováno v:
PLoS Genetics, Vol 13, Iss 2, p e1006605 (2017)
[This corrects the article DOI: 10.1371/journal.pgen.0030110.].
Externí odkaz:
https://doaj.org/article/b7a09eb129ca4173bd0c40a46c7a9979