Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Antonio Pillan"'
Autor:
Paolo Cozzi, Antonio Pillan
Publikováno v:
Journal of Heterocyclic Chemistry. 23:1693-1696
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::872c4102367dd8a8e24988400ce26095
https://doi.org/10.1002/jhet.5570230618
https://doi.org/10.1002/jhet.5570230618
Autor:
Vittorio Pinciroli, Massimo Cini, Felicita Greco, Mario Varasi, Arturo Della Torre, Carmela Speciale, Salvatore Toma, Paolo Pevarello, Antonio Pillan, Franco Heidempergher, Marina Marconi
Publikováno v:
Il Farmaco. 54:152-160
A series of pyrrolo[3,2-c]quinoline derivatives were synthesised and evaluated as inhibitors of selected enzymes of the kynurenine pathway. 7-Chloro-3-methyl-1H-pyrrolo[3,2-c]quinoline-4-carboxylic acid (7a) was found to be a relatively potent and se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a53f6f0d4074b8258714c827e372d63
https://doi.org/10.1016/s0014-827x(99)00009-9
https://doi.org/10.1016/s0014-827x(99)00009-9
Autor:
Vittorio Pinciroli, Carla Caccia, Fabrizio Vaghi, Claudio Arrigoni, Robert A. McArthur, Franco Heidempergher, Giorgio Bolis, Antonio Pillan, Luciano Dho, Mario Varasi
Publikováno v:
Journal of Medicinal Chemistry. 40:3369-3380
A possible bioisosterism between the benzamido and the phenylimidazolidin-2-one moieties has been suggested on the basis of the similarity between the molecular electrostatic potential (MEP) of metoclopramide, a D2 receptor antagonist with weak 5-HT3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d4a1dec3f8e816b983421e7f9b7288e
https://doi.org/10.1021/jm970060o
https://doi.org/10.1021/jm970060o
Autor:
Marco Tato, Paolo Orsini, Ermes Vanotti, Francesco Fiorentini, Arturo Galvani, Valter Croci, Fabrizio Orzi, Cristina Alli, Jurgen Moll, Maristella Colombo, Roberto D'Alessio, Alberto Bargiotti, Barbara Forte, Enrico Pesenti, Katia Martina, Clara Albanese, Matteo D'anello, Barbara Valsasina, Mario Varasi, Patrizia Giordano, Antonella Isacchi, Alessandra Cirla, Marcellino Tibolla, Antonio Pillan, Antonella Ciavolella, Alessandra Scolaro, Paola Vianello, Fulvia Roletto, Antonella Ermoli, Antonio Molinari, Daniele Volpi, Alessia Montagnoli, Corrado Santocanale, Maria Menichincheri, Francesco Colotta, Dario Ballinari, Marina Caldarelli
Publikováno v:
Journal of medicinal chemistry. 53(20)
Cdc7 serine/threonine kinase is a key regulator of DNA synthesis in eukaryotic organisms. Cdc7 inhibition through siRNA or prototype small molecules causes p53 independent apoptosis in tumor cells while reversibly arresting cell cycle progression in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91f5eb7387810f718a9ade2872752cfa
https://pubmed.ncbi.nlm.nih.gov/20873740
https://pubmed.ncbi.nlm.nih.gov/20873740
Publikováno v:
ChemInform. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04f85d41d66e2f75354e7b15aee05a6a
https://doi.org/10.1002/chin.199141148
https://doi.org/10.1002/chin.199141148
Autor:
Maria Gabriella Brasca, Nicoletta Colombo, Francesco Sola, Ermes Vanotti, Sandrine Thieffine, Barbara Valsasina, Daniele Volpi, Alberto Bargiotti, Antonella Ermoli, Marcellino Tibolla, Federico Riccardi Sirtori, Maria Menichincheri, Antonio Pillan, Gabriele Fachin, Antonella Ciavolella, Alessia Montagnoli, Sonia Rainoldi, Antonella Isacchi, Antonio Molinari, Corrado Santocanale
Cdc7 kinase has recently emerged as an attractive target for cancer therapy and low-molecular-weight inhibitors of Cdc7 kinase have been found to be effective in the inhibition of tumor growth in animal models. In this paper, we describe synthesis an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a42d365dd62e9d376a741dcf3f696f7
http://hdl.handle.net/10281/15097
http://hdl.handle.net/10281/15097
Autor:
Maria Menichincheri, Alessia Montagnoli, Antonella Ciavolella, Katia Martina, Ermes Vanotti, Mario Varasi, Alessandra Cirla, Roberto D'Alessio, Cinzia Cristiani, Daniele Volpi, Alessandra Scolaro, Alberto Bargiotti, Barbara Valsasina, Marcellino Tibolla, Roberta Bosotti, Antonella Isacchi, Raffaella Amici, Antonio Pillan, Paolo Orsini, Barbara Forte, Antonio Molinari, Fulvia Roletto, Jens Berthelsen, Corrado Santocanale
Cdc7 kinase is an essential protein that promotes DNA replication in eukaryotic organisms. Genetic evidence indicates that Cdc7 inhibition can cause selective tumor-cell death in a p53-independent manner, supporting the rationale for developing Cdc7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b8177c69e67dae7b2d00ac0785fd36e
http://hdl.handle.net/2318/93819
http://hdl.handle.net/2318/93819
Autor:
Ermes Vanotti, Raffaella Amici, Alberto Bargiotti, Jens Berthelsen, Roberta Bosotti, Antonella Ciavolella, Alessandra Cirla, Cinzia Cristiani, Roberto D’Alessio, Barbara Forte, Antonella Isacchi, Katia Martina, Maria Menichincheri, Antonio Molinari, Alessia Montagnoli, Paolo Orsini, Antonio Pillan, Fulvia Roletto, Alessandra Scolaro, Marcellino Tibolla
Publikováno v:
Journal of Medicinal Chemistry; Jan2008, Vol. 51 Issue 3, p487-501, 15p
Publikováno v:
Journal of Medicinal Chemistry. 29:404-410
A series of 3-(1-imidazolyl)chroman-4-ones and 2-(1-imidazolyl)-1-tetralones II, some of their alcohols, and some related compounds were synthesized and tested for hypolipidemic activity. Compounds II, bearing appropriate lipophilic substituents on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb3e13453b84aacd0970c2cb9241cc73
https://doi.org/10.1021/jm00153a016
https://doi.org/10.1021/jm00153a016
Autor:
Antonio Pillan, Paolo Cozzi
Publikováno v:
Journal of Heterocyclic Chemistry. 25:1613-1616
The synthesis of 2-(1H-imidazol-1-yl)-4H-1-benzothiopyran-4-ones 3 from 3-bromo-4H-1-benzothiopyran-4-ones 1 and imidazole is described. The reaction of 1 with secondary amines gives the corresponding 3-amino-thiochromones 11. Compounds 3 can be oxid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::316e2a546be8d013849a3459f74add67
https://doi.org/10.1002/jhet.5570250603
https://doi.org/10.1002/jhet.5570250603