Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Antonio Pezone"'
Autor:
Michele Rinaldi, Antonio Pezone, Gaia Italia Quadrini, Gianmarco Abbadessa, Maria Paola Laezza, Maria Laura Passaro, Antonio Porcellini, Ciro Costagliola
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
The intricate parallels in structure and function between the human retina and the central nervous system designate the retina as a prospective avenue for understanding brain-related processes. This review extensively explores the shared physiopathol
Externí odkaz:
https://doaj.org/article/7915aceac267461d9ece038f82e44e06
Autor:
Cristina Terlizzi, Viviana De Rosa, Francesca Iommelli, Antonio Pezone, Giovanna G. Altobelli, Maurizio Maddalena, Jelena Dimitrov, Caterina De Rosa, Carminia Maria Della Corte, Vittorio Enrico Avvedimento, Silvana Del Vecchio
Publikováno v:
Cancer & Metabolism, Vol 11, Iss 1, Pp 1-11 (2023)
Abstract Background ATM is a multifunctional serine/threonine kinase that in addition to its well-established role in DNA repair mechanisms is involved in a number of signaling pathways including regulation of oxidative stress response and metabolic
Externí odkaz:
https://doaj.org/article/e83d3991835d4c898a45587c3d859097
Autor:
Annarita Nappi, Caterina Miro, Antonio Pezone, Alfonso Tramontano, Emery Di Cicco, Serena Sagliocchi, Annunziata Gaetana Cicatiello, Melania Murolo, Sepehr Torabinejad, Elena Abbotto, Giuseppina Caiazzo, Maddalena Raia, Mariano Stornaiuolo, Dario Antonini, Gabriella Fabbrocini, Domenico Salvatore, Vittorio Enrico Avvedimento, Monica Dentice
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Thyroid hormones have an important role in fostering tumour progression, however their upstream regulators are less clear. Here, the authors identify the thyroid hormone activating enzyme type 2 deiodinase as a p53 target gene and demonstrate its con
Externí odkaz:
https://doaj.org/article/da3123fe17794adebd580a7ea85ffb2e
Autor:
Antonella Sarnataro, Giulia De Riso, Sergio Cocozza, Antonio Pezone, Barbara Majello, Stefano Amente, Giovanni Scala
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 5925-5934 (2022)
DNA methylation is an epigenetic modification that plays a pivotal role in major biological mechanisms, such as gene regulation, genomic imprinting, and genome stability. Different combinations of methylated cytosines for a given DNA locus generate d
Externí odkaz:
https://doaj.org/article/e64454b8a7674394b691b7f6ee98885e
Autor:
Bruno Perillo, Marzia Di Donato, Antonio Pezone, Erika Di Zazzo, Pia Giovannelli, Giovanni Galasso, Gabriella Castoria, Antimo Migliaccio
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 2, Pp 192-203 (2020)
Cancer: A Trojan horse to kill cancer cells Highly reactive molecules called reactive oxygen species (ROS), which at low levels are natural regulators of important signaling pathways in cells, might be recruited to act as “Trojan horses” to kill
Externí odkaz:
https://doaj.org/article/3ff956a3ec744f26908fe41f22788e76
Autor:
Alfonso Tramontano, Francesca Ludovica Boffo, Giusi Russo, Mariarosaria De Rosa, Ilaria Iodice, Antonio Pezone
Publikováno v:
Biomolecules, Vol 10, Iss 3, p 446 (2020)
Tumor suppressor genes in the CDKN2A/B locus (p15INK4b, p16INK4a, and p14ARF) function as biological barriers to transformation and are the most frequently silenced or deleted genes in human cancers. This gene silencing frequently occurs due to DNA m
Externí odkaz:
https://doaj.org/article/1ff10d81549f43ceaaebb38b52715ea5
Autor:
Tiziana Angrisano, Raffaela Pero, Mariarita Brancaccio, Lorena Coretti, Ermanno Florio, Antonio Pezone, Viola Calabrò, Geppino Falco, Simona Keller, Francesca Lembo, Vittorio Enrico Avvedimento, Lorenzo Chiariotti
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156671 (2016)
Bacterial lipopolysaccharide (LPS) induces release of inflammatory mediators both in immune and epithelial cells. We investigated whether changes of epigenetic marks, including selected histone modification and DNA methylation, may drive or accompany
Externí odkaz:
https://doaj.org/article/5608657e1071474dae3d2a39cba366bf
Autor:
Antonio Pezone, Fabiola Olivieri, Maria Vittoria Napoli, Antonio Procopio, Enrico Vittorio Avvedimento, Armando Gabrielli
Publikováno v:
Nature Reviews Rheumatology. 19:200-211
Inflammation is a biological response involving immune cells, blood vessels and mediators induced by endogenous and exogenous stimuli, such as pathogens, damaged cells or chemicals. Unresolved (chronic) inflammation is characterized by the secretion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bea8a7b5979132cf796e9f357838a49b
https://doi.org/10.1038/s41584-022-00905-1
https://doi.org/10.1038/s41584-022-00905-1
Autor:
Antonietta Liotti, Anne Lise Ferrara, Stefania Loffredo, Maria Rosaria Galdiero, Gilda Varricchi, Francesca Di Rella, Giorgia Teresa Maniscalco, Martina Belardo, Roberta Vastano, Rosaria Prencipe, Laura Pignata, Roberta Romano, Giuseppe Spadaro, Paola de Candia, Antonio Pezone, Veronica De Rosa
Publikováno v:
Immunology. 167:451-470
Epigenetics connects genetic and environmental factors: it includes DNA methylation, histone post-translational modifications and the regulation of chromatin accessibility by non-coding RNAs, all of which control constitutive or inducible gene transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be4c346df8e8f4876c3dc0bf1ca5e1b7
https://doi.org/10.1111/imm.13571
https://doi.org/10.1111/imm.13571
Autor:
Teresa Improda, Valentina Morgera, Maria Vitale, Fabiana Passaro, Antonia Feola, Antonio Porcellini, Mariella Cuomo, Antonio Pezone
Cell identity is determined by chromatin structure and the profiles of gene expression, which are dependent on chromatin accessibility and DNA methylation of regions critical for gene expres-sions, such as enhancers and promoters. These epigenetic mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6f9056c421adc9ab27eb3351f835a6f
https://doi.org/10.20944/preprints202305.2052.v1
https://doi.org/10.20944/preprints202305.2052.v1
