Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Antonio PEÓN"'
Publikováno v:
BMC Medical Genomics, Vol 11, Iss 1, Pp 1-14 (2018)
Abstract Background Oncology drugs are only effective in a small proportion of cancer patients. Our current ability to identify these responsive patients before treatment is still poor in most cases. Thus, there is a pressing need to discover respons
Externí odkaz:
https://doaj.org/article/5fafe98679334e91bb0fa84f870245d3
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Many computational methods to predict the macromolecular targets of small organic molecules have been presented to date. Despite progress, target prediction methods still have important limitations. For example, the most accurate methods imp
Externí odkaz:
https://doaj.org/article/d3c61d3ca21340c9835c42f70e3c47ad
Autor:
Matti Javanainen, Salla I. Virtanen, Fernando Favela-Rosales, Chris Papadopoulos, Antonio Peón, Amélie Bacle, Anne M. Kiirikki, Patrick F.J. Fuchs, O. H. Samuli Ollila, Pavel Buslaev, Ángel Piñeiro, Rebeca García-Fandiño, Paula Milán Rodríguez, Tiago Mendes Ferreira, Markus S. Miettinen, Jesper J. Madsen, Josef Melcr, Ivan Gushchin, Thomas J. Piggot
Publikováno v:
Journal of the American Chemical Society
Journal of the American Chemical Society, 2021, 143 (34), pp.13701-13709. ⟨10.1021/jacs.1c05549⟩
Journal of the American Chemical Society, 143(34), 13701-13709. AMER CHEMICAL SOC
Journal of the American Chemical Society, American Chemical Society, 2021, 143 (34), pp.13701-13709. ⟨10.1021/jacs.1c05549⟩
Journal of the American Chemical Society, 2021, 143 (34), pp.13701-13709. ⟨10.1021/jacs.1c05549⟩
Journal of the American Chemical Society, 143(34), 13701-13709. AMER CHEMICAL SOC
Journal of the American Chemical Society, American Chemical Society, 2021, 143 (34), pp.13701-13709. ⟨10.1021/jacs.1c05549⟩
International audience; Interest in lipid interactions with proteins and other biomolecules is emerging not only in fundamental biochemistry but also in the field of nanobiotechnology where lipids are commonly used, for example, in carriers of mRNA v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d9345531ed2d3d157ba5bfda9d2f8b
https://hal.sorbonne-universite.fr/hal-03355166/file/jacs.1c05549.pdf
https://hal.sorbonne-universite.fr/hal-03355166/file/jacs.1c05549.pdf
Autor:
Eva González-Freire, Rebeca García-Fandiño, Bárbara Claro, Antonio Peón, Erik Goormaghtigh, Manuel Amorín, Margarida Bastos, Juan R. Granja
Publikováno v:
Colloids and surfaces. B, Biointerfaces. 208
Antimicrobial peptides are viewed as a promising alternative to conventional antibiotics, as their activity through membrane targeting makes them less prone to resistance development. Among them, antimicrobial D,L-α-cyclic peptides (CPs) have been p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce0c803d233eb11ec016604523cdf97c
https://pubmed.ncbi.nlm.nih.gov/34492602
https://pubmed.ncbi.nlm.nih.gov/34492602
Autor:
Antonio PEÓN
Simulation of a POPG bilayer of 500 lipids (250 per leaflet) is simulated for 500 ns using Gromacs v2018.3 in water solution with Na+ counterions. The SLIPID model is employed for lipids and the TIP3P model for water. Trajectory (.xtc) is for the las
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04e46b5f87804351641590bba426a589
Autor:
Ghita Ghislat, Hongjian Li, Antonio Peón, Pedro J. Ballester, Man Hon Wong, Gang Lu, Kwong-Sak Leung
Publikováno v:
Chemical Biology & Drug Design
Chemical Biology & Drug Design, 2019, 94 (1), pp.1390-1401. ⟨10.1111/cbdd.13516⟩
Chemical Biology & Drug Design, 2019, 94 (1), pp.1390-1401. ⟨10.1111/cbdd.13516⟩
Molecular target prediction can provide a starting point to understand the efficacy and side effects of phenotypic screening hits. Unfortunately, the vast majority of in silico target prediction methods are not available as web tools. Furthermore, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f42602b70f5abb126c9b8301907f0ca
https://hal.science/hal-02359436
https://hal.science/hal-02359436
Publikováno v:
BMC Medical Genomics
BMC Medical Genomics, BioMed Central, 2018, 11 (1), pp.10. ⟨10.1186/s12920-018-0336-z⟩
BMC Medical Genomics, 2018, 11 (1), pp.10. ⟨10.1186/s12920-018-0336-z⟩
BMC Medical Genomics, Vol 11, Iss 1, Pp 1-14 (2018)
BMC Medical Genomics, BioMed Central, 2018, 11 (1), pp.10. ⟨10.1186/s12920-018-0336-z⟩
BMC Medical Genomics, 2018, 11 (1), pp.10. ⟨10.1186/s12920-018-0336-z⟩
BMC Medical Genomics, Vol 11, Iss 1, Pp 1-14 (2018)
BackgroundOncology drugs are only effective in a small proportion of cancer patients. Our current ability to identify these responsive patients before treatment is still poor in most cases. Thus, there is a pressing need to discover response markers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4793e1b9f32866c6731605a254e78b76
https://www.hal.inserm.fr/inserm-01706250/file/12920_2018_Article_336.pdf
https://www.hal.inserm.fr/inserm-01706250/file/12920_2018_Article_336.pdf
Publikováno v:
Frontiers in Chemistry
Frontiers in Chemistry, 2016, 4, pp.15-15. ⟨10.3389/fchem.2016.00015⟩
Frontiers in Chemistry, Frontiers Media, 2016, 4, pp.15-15. ⟨10.3389/fchem.2016.00015⟩
Frontiers in Chemistry, Vol 4 (2016)
Frontiers in Chemistry, 2016, 4, pp.15-15. ⟨10.3389/fchem.2016.00015⟩
Frontiers in Chemistry, Frontiers Media, 2016, 4, pp.15-15. ⟨10.3389/fchem.2016.00015⟩
Frontiers in Chemistry, Vol 4 (2016)
Computational methods for Target Fishing (TF), also known as Target Prediction or Polypharmacology Prediction, can be used to discover new targets for small-molecule drugs. This may result in repositioning the drug in a new indication or improving ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61ec8a0c1bbb76b6a26399fb7e3a1358
https://hal-amu.archives-ouvertes.fr/hal-01785656/document
https://hal-amu.archives-ouvertes.fr/hal-01785656/document