Zobrazeno 1 - 10
of 146
pro vyhledávání: '"Antonio Mera"'
Autor:
Yousof Farrag, Mariam Farrag, María Varela-García, Carlos Torrijos-Pulpón, Maurizio Capuozzo, Alessando Ottaiano, Francisca Lago, Antonio Mera, Jesus Pino, Oreste Gualillo
Publikováno v:
Pharmacological Research, Vol 205, Iss , Pp 107219- (2024)
Adipokines are a heterogeneous group of signalling molecules secreted prevalently by adipose tissue. Initially considered as regulators of energy metabolism and appetite, adipokines have been recognized for their substantial involvement in musculoske
Externí odkaz:
https://doaj.org/article/8d6b2cff04944e6898261dfdffc45207
Autor:
Lorena Rodriguez-Martinez, Cristina García-Moreno, Eva Perez-Pampin, María J. Gómara, Juan C. Sarmiento-Monroy, Yolanda Lopez-Golán, José A. Gómez-Puerta, Antonio Mera-Varela, Carmen Conde, Raimon Sanmartí, Isabel Haro, Antonio González
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-14 (2023)
Abstract Background Autoantibodies are critical elements in RA pathogenesis and clinical assessment. The anti-malondialdehyde-acetaldehyde (anti-MAA) antibodies are potentially useful because of their claimed high sensitivity for all RA patients, inc
Externí odkaz:
https://doaj.org/article/fe7bfc8d419849f68d300c670efe5da0
Autor:
Mariam Farrag, Djedjiga Ait Eldjoudi, María González-Rodríguez, Alfonso Cordero-Barreal, Clara Ruiz-Fernández, Maurizio Capuozzo, Miguel Angel González-Gay, Antonio Mera, Francisca Lago, Ahmed Soffar, Amina Essawy, Jesus Pino, Yousof Farrag, Oreste Gualillo
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2023)
Adipose tissue malfunction leads to altered adipokine secretion which might consequently contribute to an array of metabolic diseases spectrum including obesity, diabetes mellitus, and cardiovascular disorders. Asprosin is a novel diabetogenic adipok
Externí odkaz:
https://doaj.org/article/9e9f20c128e443469bf0dff806d879cb
Autor:
Angela Rodríguez-Trillo, Carmen Pena, Samuel García, Eva Pérez-Pampín, Marina Rodríguez-López, Antonio Mera-Varela, Antonio González, Carmen Conde
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Rheumatoid arthritis (RA) is a common chronic inflammatory disease affecting primarily peripheral joints, which is only partially controlled with current treatments. RA leads to pain, disability, deformities, and life expectancy shortening. Its patho
Externí odkaz:
https://doaj.org/article/f19d80d9b6eb4d9e9aa70b2e7b91b2f2
Autor:
María González-Rodríguez, Djedjiga Ait Edjoudi, Alfonso Cordero Barreal, Clara Ruiz-Fernández, Mariam Farrag, Beatriz González-Rodríguez, Francisca Lago, Maurizio Capuozzo, Miguel Angel Gonzalez-Gay, Antonio Mera Varela, Jesús Pino, Yousof Farrag, Oreste Gualillo
Publikováno v:
Pharmaceuticals, Vol 15, Iss 12, p 1544 (2022)
Progranulin (PGRN) is a glycoprotein formed by 593 amino acids encoded by the GRN gene. It has an important role in immunity and inflammatory response, as well as in tissue recovery. Its role in musculoskeletal inflammatory diseases such as rheumatoi
Externí odkaz:
https://doaj.org/article/8a8be35fd55748299b2e4cb790294f86
Autor:
Angela Rodriguez-Trillo, Nerea Mosquera, Carmen Pena, Fatima Rivas-Tobío, Antonio Mera-Varela, Antonio Gonzalez, Carmen Conde
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
We hypothesized that WNT5A could contribute to the enhanced migration and invasiveness of rheumatoid arthritis fibroblast-like synoviocytes (RA FLS), which is one of the incompletely understood aspects of the RA FLS aggressive phenotype. This hypothe
Externí odkaz:
https://doaj.org/article/a278667b816d4d3cb3703d4f60311c7b
Autor:
Djedjiga Ait Eldjoudi, Alfonso Cordero Barreal, María Gonzalez-Rodríguez, Clara Ruiz-Fernández, Yousof Farrag, Mariam Farrag, Francisca Lago, Maurizio Capuozzo, Miguel Angel Gonzalez-Gay, Antonio Mera Varela, Jesús Pino, Oreste Gualillo
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 5, p 2859 (2022)
White adipose tissue (WAT) is a specialized tissue whose main function is lipid synthesis and triglyceride storage. It is now considered as an active organ secreting a plethora of hormones and cytokines namely adipokines. Discovered in 1994, leptin h
Externí odkaz:
https://doaj.org/article/96ceea4534524cbba4206e189e076303
Autor:
Lorena Rodríguez-Martínez, Cristina Regueiro, Sámer Amhaz-Escanlar, Carmen Pena, Paloma Herbello-Hermelo, Antonio Moreda-Piñeiro, Javier Rodriguez-Garcia, Antonio Mera-Varela, Eva Pérez-Pampín, Antonio González
Publikováno v:
Diagnostics, Vol 12, Iss 2, p 352 (2022)
Patients with rheumatoid arthritis (RA) show autoantibodies against post-translational protein modifications (PTMs), such as anti-citrullinated protein antibodies. However, the range of recognized PTMs is unknown. Here, we addressed four PTMs: chlori
Externí odkaz:
https://doaj.org/article/3f09cc9b925e4015b598fe39b05e5848
Autor:
Rosario López-Rodríguez, Aida Ferreiro-Iglesias, Aurea Lima, Miguel Bernardes, Andrzej Pawlik, Agnieszka Paradowska-Gorycka, Jerzy Świerkot, Ryszard Slezak, Vita Dolžan, Isidoro González-Álvaro, Javier Narváez, Rafael Cáliz, Eva Pérez-Pampín, Antonio Mera-Varela, Laura Vidal-Bralo, José Gorgonio Acuña Ochoa, Carmen Conde, Juan J. Gómez-Reino, Antonio González
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Abstract About 70 genetic studies have already addressed the need of biomarkers to predict the response of patients with rheumatoid arthritis (RA) to methotrexate (MTX) treatment. However, no genetic biomarker has yet been sufficiently validated. Her
Externí odkaz:
https://doaj.org/article/2feae63c8b2a4e138135868ba1a187e3
Autor:
Cristina Guillín-Amarelle, Sofía Sánchez-Iglesias, Antonio Mera, Elena Pintos, Ana Castro-Pais, Leticia Rodríguez-Cañete, Julio Pardo, Felipe F. Casanueva, David Araújo-Vilar
Publikováno v:
Archives of Endocrinology and Metabolism, Vol 62, Iss 3, Pp 376-382 (2018)
Summary Laminopathies are genetic disorders associated with alterations in nuclear envelope proteins, known as lamins. The LMNA gene encodes lamins A and C, and LMNA mutations have been linked to diseases involving fat (type 2 familial partial lipody
Externí odkaz:
https://doaj.org/article/b68dc6605c864d61bc1df3bcd6f822c1