Zobrazeno 1 - 10
of 196
pro vyhledávání: '"Antonio Marchal"'
Unveiling the microRNA landscape in pancreatic ductal adenocarcinoma patients and cancer cell models
Autor:
Grazia Fenu, Carmen Griñán-Lisón, Andrea Pisano, Aitor González-Titos, Cristiano Farace, Giovanni Fiorito, Federica Etzi, Teresa Perra, Angela Sabalic, Belén Toledo, Macarena Perán, Maria Giuliana Solinas, Alberto Porcu, Juan Antonio Marchal, Roberto Madeddu
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) poses a significant challenge due to late-stage diagnoses resulting from nonspecific early symptoms and the absence of early diagnostic biomarkers. MicroRNAs (miRNAs) play a crucial role in
Externí odkaz:
https://doaj.org/article/92f9560de5734c30960654cf42e7dd4c
Autor:
Julia López de Andrés, César Rodríguez-Santana, Laura de Lara-Peña, Gema Jiménez, Germaine Escames, Juan Antonio Marchal
Publikováno v:
Materials Today Bio, Vol 29, Iss , Pp 101246- (2024)
Head and neck squamous cell carcinoma (HNSCC) presents a significant challenge worldwide due to its aggressiveness and high recurrence rates post-treatment, often linked to cancer stem cells (CSCs). Melatonin shows promise as a potent tumor suppresso
Externí odkaz:
https://doaj.org/article/7cbfd1e5d849460395d10bbfaa529649
Autor:
Belén Toledo, Linrui Zhu Chen, María Paniagua-Sancho, Juan Antonio Marchal, Macarena Perán, Elisa Giovannetti
Publikováno v:
Journal of Hematology & Oncology, Vol 17, Iss 1, Pp 1-34 (2024)
Abstract Macrophages infiltrating tumour tissues or residing in the microenvironment of solid tumours are known as tumour-associated macrophages (TAMs). These specialized immune cells play crucial roles in tumour growth, angiogenesis, immune regulati
Externí odkaz:
https://doaj.org/article/04bae7a90baa4ad0a0fd1a84ab9ec11f
Autor:
Cristina Galocha-León, Cristina Antich, Beatriz Clares-Naveros, Ana Voltes-Martínez, Juan Antonio Marchal, Patricia Gálvez-Martín
Publikováno v:
Pharmaceutics, Vol 16, Iss 11, p 1422 (2024)
Background/Objectives: Three-dimensional bioprinting technology has enabled great advances in the treatment of articular cartilage (AC) defects by the biofabrication of biomimetic constructs that restore and/or regenerate damaged tissue. In this sens
Externí odkaz:
https://doaj.org/article/06229a19304b4f4ebb707b51906bd3ab
Autor:
María Tristán-Manzano, Noelia Maldonado-Pérez, Pedro Justicia-Lirio, Marina Cortijo-Gutierréz, Pablo Tristán-Ramos, Carlos Blanco-Benítez, Kristina Pavlovic, Araceli Aguilar-González, Pilar Muñoz, Francisco J. Molina-Estevez, Valerie Griesche, Juan Antonio Marchal, Sara R. Heras, Karim Benabdellah, Francisco Martin
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 322-339 (2023)
Controlling transgene expression through an externally administered inductor is envisioned as a potent strategy to improve safety and efficacy of gene therapy approaches. Generally, inducible ON systems require a chimeric transcription factor (transa
Externí odkaz:
https://doaj.org/article/5e23d31a5c5e4bcd886b94089d46f8e8
Autor:
Carmen González‐Olmedo, Francisco José García‐Verdejo, Antonio Reguera‐Teba, Carmen Rosa‐Garrido, José Antonio López‐López, Leticia Díaz‐Beltrán, Patricia Mena García, Natalia Luque‐Caro, Fernando Gálvez‐Montosa, Ana Laura Ortega‐Granados, María Ruiz‐Sanjuan, Antonio Cózar‐Ibáñez, Juan Sainz, Juan Antonio Marchal, José Camacho, José Pérez delPalacio, Rosario Fernández‐Godino, Caridad Díaz, Pedro Sánchez‐Rovira
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 1, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/7b4ca450c8c744ecbc50aea1cb5911cf
Autor:
Aixa Aguilera-Garrido, Elena Arranz, María José Gálvez-Ruiz, Juan Antonio Marchal, Francisco Galisteo-González, Linda Giblin
Publikováno v:
Drug Delivery, Vol 29, Iss 1, Pp 1971-1982 (2022)
Maslinic acid (MA) is a plant-derived, low water-soluble compound with antitumor activity. We have formulated MA in the form of solid lipid nanoparticles (SLNs) with three different shell compositions: Poloxamer 407 (PMA), dicarboxylic acid-Poloxamer
Externí odkaz:
https://doaj.org/article/1ea81d5307d44d11b838bbf713bf4383
Autor:
Pablo Graván, Sara Rojas, Darina Francesca Picchi, Francisco Galisteo-González, Patricia Horcajada, Juan Antonio Marchal
Publikováno v:
Nanomaterials, Vol 14, Iss 9, p 784 (2024)
The recent description of well-defined molecular subtypes of breast cancer has led to the clinical development of a number of successful molecular targets. Particularly, triple-negative breast cancer (TNBC) is an aggressive type of breast cancer with
Externí odkaz:
https://doaj.org/article/6844c462c0eb40c28efd4d0c482ae245
Autor:
Paula Pleguezuelos-Beltrán, Patricia Gálvez-Martín, Daniel Nieto-García, Juan Antonio Marchal, Elena López-Ruiz
Publikováno v:
Bioactive Materials, Vol 16, Iss , Pp 187-203 (2022)
To date, skin wounds are still an issue for healthcare professionals. Although numerous approaches have been developed over the years for skin regeneration, recent advances in regenerative medicine offer very promising strategies for the fabrication
Externí odkaz:
https://doaj.org/article/55f60a1ea20e42ebbc353927f8828c1c
Autor:
Caridad Díaz, Carmen González‐Olmedo, Leticia Díaz‐Beltrán, José Camacho, Patricia Mena García, Ariadna Martín‐Blázquez, Mónica Fernández‐Navarro, Ana Laura Ortega‐Granados, Fernando Gálvez‐Montosa, Juan Antonio Marchal, Francisca Vicente, José Pérez del Palacio, Pedro Sánchez‐Rovira
Publikováno v:
Molecular Oncology, Vol 16, Iss 14, Pp 2658-2671 (2022)
Neoadjuvant chemotherapy (NACT) outcomes vary according to breast cancer (BC) subtype. Since pathologic complete response is one of the most important target endpoints of NACT, further investigation of NACT outcomes in BC is crucial. Thus, identifyin
Externí odkaz:
https://doaj.org/article/8e897a0c9b45412993f888401393b048