Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Antonio Maffia"'
Autor:
Timothy K. Turkalo, Antonio Maffia, Johannes J. Schabort, Samuel G. Regalado, Mital Bhakta, Marco Blanchette, Diana C. J. Spierings, Peter M. Lansdorp, Dirk Hockemeyer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Mutations of ATRX are frequent in cancers that immortalize through the ALT (Alternative lengthening of telomeres) pathway. Here the authors show that ALT features are repressed in embryonic stem cells that lack ATRX but induced by continuous telomere
Externí odkaz:
https://doaj.org/article/c82b5c4319a248149ad833c8327f0f16
Publikováno v:
Data in Brief, Vol 20, Iss , Pp 1148-1152 (2018)
The data in this article are related to the research article titled “Reproducible Stencil Compiler Benchmarks Using PROVA!”. Stencil kernels have been implemented using a naïve OpenMP (OpenMP Architecture Review Board, 2016) [1] parallelization
Externí odkaz:
https://doaj.org/article/6f6a75b2f0e44965aa234ac9ae6f1fd2
Publikováno v:
Frontiers in Genetics, Vol 7 (2016)
DNA replication is an extremely complex process that needs to be executed in a highly accurate manner in order to propagate the genome. This task requires the coordination of a number of enzymatic activities and it is incredibly fragile and prone to
Externí odkaz:
https://doaj.org/article/18b9a94284194fcab86624c89e4020ab
UBR5 interacts with the replication fork and protects DNA replication from DNA polymerase η toxicity
Autor:
Chih-Chao Liang, Alan R. Lehmann, Martin A. Cohn, Federica Bertoletti, Simone Sabbioneda, Lina Cipolla, Antonio Maffia
Publikováno v:
Nucleic Acids Research
Accurate DNA replication is critical for the maintenance of genome integrity and cellular survival. Cancer-associated alterations often involve key players of DNA replication and of the DNA damage-signalling cascade. Post-translational modifications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b73da0f9d7cdf36a841ae9c182c6d62c
https://doi.org/10.1093/nar/gkz824
https://doi.org/10.1093/nar/gkz824
Publikováno v:
Future Generation Computer Systems. 92:933-946
The stencil pattern represents a vast variety of applications, ranging from geophysics to medical science. In application codes, the stencil kernel is often the part where most of the time is spent, thus forcing an efficient parallel implementation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b2aac43de5e113feccfdaf9d9679a1e
https://doi.org/10.1016/j.future.2018.05.023
https://doi.org/10.1016/j.future.2018.05.023
Autor:
Fabrizio d'Adda di Fagagna, Sofia Francia, Antonio Maffia, Lina Cipolla, Simone Sabbioneda, Matteo Cabrini, Fabio Iannelli, Alessandro Galbiati, Marco Roncador
Publikováno v:
Journal of Cell Science
article-version (VoR) Version of Record
article-version (VoR) Version of Record
The DNA damage response (DDR) is the signaling cascade that recognizes DNA double-strand breaks (DSBs) and promotes their resolution via the DNA repair pathways of non-homologous end joining (NHEJ) or homologous recombination (HR). We and others have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b44717b661cc59422e28ed1b26f09a5
https://www.zora.uzh.ch/id/eprint/207429/
https://www.zora.uzh.ch/id/eprint/207429/
Autor:
Ulrich Hübscher, Silvia Galli, Giovanni Maga, Silvia Bione, Joachim Lingner, Emmanuele Crespan, Fabrizio d'Adda di Fagagna, Miroslava Kissova, Elisa Zucca, Valérie Bergoglio, Elena Ferrari, Sofia Francia, Simone Sabbioneda, Liuh-Yow Chen, Giulia Tagliavini, Federica Bertoletti, Elisa Mentegari, Antonio Maffia, Anna Garbelli, Jean-Sébastien Hoffmann
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2021, 22 (5), pp.2365. ⟨10.3390/ijms22052365⟩
International Journal of Molecular Sciences, Vol 22, Iss 2365, p 2365 (2021)
Volume 22
Issue 5
International Journal of Molecular Sciences, MDPI, 2021, 22 (5), pp.2365. ⟨10.3390/ijms22052365⟩
International Journal of Molecular Sciences, Vol 22, Iss 2365, p 2365 (2021)
Volume 22
Issue 5
International audience; Telomerase negative cancer cell types use the Alternative Lengthening of Telomeres (ALT) pathway to elongate telomeres ends. Here, we show that silencing human DNA polymerase (Pol λ) in ALT cells represses ALT activity and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04c5142fb9ab19ec3f96dfa6f03a9527
https://hal.archives-ouvertes.fr/hal-03407923
https://hal.archives-ouvertes.fr/hal-03407923
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1506 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1506 (2020)
Replicating the entire genome is one of the most complex tasks for all organisms. Research carried out in the last few years has provided us with a clearer picture on how cells preserve genomic information from the numerous insults that may endanger
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7c340af14fba29f8d8fa7bcb8d6489f
https://pubmed.ncbi.nlm.nih.gov/32098397
https://pubmed.ncbi.nlm.nih.gov/32098397
Autor:
Luca Bini, Anna Garbelli, Federica Casiraghi, Martina Schroeder, Francesca Arena, Antonio Maffia, Valentina Riva, Claudia Immacolata Trivisani, Giovanni Maga, Simone Sabbioneda, Assunta Gagliardi
Publikováno v:
Nucleic Acids Research
Removal of ribonucleotides (rNMPs) incorporated into the genome by the ribonucleotide excision repair (RER) is essential to avoid genetic instability. In eukaryotes, the RNaseH2 is the only known enzyme able to incise 5′ of the rNMP, starting the R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::434f6b2c12d3ed8eb9fba2b1abbb05f6
https://mural.maynoothuniversity.ie/14960/
https://mural.maynoothuniversity.ie/14960/