Zobrazeno 1 - 10
of 793
pro vyhledávání: '"Antonio M Gotto"'
Autor:
Gurpreet Singh, Yasin Hussain, Zhuoran Xu, Evan Sholle, Kelly Michalak, Kristina Dolan, Benjamin C Lee, Alexander R van Rosendael, Zahra Fatima, Jessica M Peña, Peter W F Wilson, Antonio M Gotto, Leslee J Shaw, Lohendran Baskaran, Subhi J Al'Aref
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0239934 (2020)
BackgroundLow-density lipoprotein cholesterol (LDL-C) is a target for cardiovascular prevention. Contemporary equations for LDL-C estimation have limited accuracy in certain scenarios (high triglycerides [TG], very low LDL-C).ObjectivesWe derived a n
Externí odkaz:
https://doaj.org/article/bdb9302469f54393b7d2c95f6e14425d
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159130 (2016)
There is emerging evidence identifying microRNAs (miRNAs) as mediators of statin-induced cholesterol efflux, notably through the ATP-binding cassette transporter A1 (ABCA1) in macrophages. The objective of this study was to assess the impact of an HM
Externí odkaz:
https://doaj.org/article/02427ad663024f2bad9dd9b2084fb02a
Autor:
Ziyi Wang, Dedipya Yelamanchili, Jing Liu, Antonio M. Gotto, Jr., Corina Rosales, Baiba K. Gillard, Henry J. Pownall
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 11, Pp 100456- (2023)
Compared with WT mice, HDL receptor-deficient (Scarb1−/−) mice have higher plasma levels of free cholesterol (FC)-rich HDL and exhibit multiple pathologies associated with a high mol% FC in ovaries, platelets, and erythrocytes, which are reversed
Externí odkaz:
https://doaj.org/article/9ab64245fa4046f68267f451fcd9985d
Autor:
Antonio M. Gotto, Jennifer Moon
Weill Cornell Medicine is a story of continuity and transformation. Throughout its colorful history, Cornell's medical school has been a leader in education, patient care, and research—from its founding as Cornell University Medical College in 1898
Autor:
Corina Rosales, Dedipya Yelamanchili, Baiba K. Gillard, Jing Liu, Antonio M. Gotto, Jr., Henry J. Pownall
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 2, Pp 100327- (2023)
Human female infertility, 20% of which is idiopathic, is a public health problem for which better diagnostics and therapeutics are needed. A novel cause of infertility emerged from studies of female mice deficient in the HDL receptor gene (Scarb1). T
Externí odkaz:
https://doaj.org/article/60746f5620db47cc9e142c6c9b7a6e52
Autor:
Erik S.G. Stroes, Harold E. Bays, Maciej Banach, Alberico L. Catapano, P. Barton Duell, Ulrich Laufs, G.B. John Mancini, Kausik K. Ray, William J. Sasiela, Yang Zhang, Antonio M. Gotto
Publikováno v:
Atherosclerosis, 373, 1-9. Elsevier Ireland Ltd
Background and aims: High-sensitivity C-reactive protein (hsCRP), a marker for atherosclerotic cardiovascular disease risk, is reduced by bempedoic acid. We assessed the relationship between changes in low-density lipoprotein cholesterol (LDL-C) and
Autor:
Andrew J. Buckler, Antonio M. Gotto, Akshay Rajeev, Anna Nicolaou, Atsushi Sakamoto, Samantha St Pierre, Matthew Phillips, Renu Virmani, Todd C. Villines
Publikováno v:
Atherosclerosis.
The application of machine learning to assess plaque risk phenotypes on cardiovascular CT angiography (CTA) is an area of active investigation. Studies using accepted histologic definitions of plaque risk as ground truth for machine learning models a
Publikováno v:
Nature Reviews Cardiology. 18:712-723
Plasma HDL-cholesterol concentrations correlate negatively with the risk of atherosclerotic cardiovascular disease (ASCVD). According to a widely cited model, HDL elicits its atheroprotective effect through its role in reverse cholesterol transport,
Autor:
Corina, Rosales, Dedipya, Yelamanchili, Baiba K, Gillard, Jing, Liu, Antonio M, Gotto, Henry J, Pownall
Publikováno v:
Journal of lipid research.
Human female infertility, 20% of which is idiopathic, is a public health problem for which better diagnostics and therapeutics are needed. A novel cause of infertility emerged from studies of female mice deficient in the HDL receptor gene (Scarb1). T
Autor:
Baiba K Gillard, Ziyi Wang, Jing Liu, Dedipya Yelamanchili, Antonio M Gotto, Corina Rosales, Henry J Pownall
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
Aim: In humans, very high plasma HDL-cholesterol concentrations are associated with increased all cause- and atherosclerotic cardiovascular disease (ASCVD)-mortality. The HDL receptor-deficient mouse (Scarb1 -/- ) is a robust model of this phenotype