Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Antonio Luis Egea-Jimenez"'
Autor:
Rudra Kashyap, Marielle Balzano, Benoit Lechat, Kathleen Lambaerts, Antonio Luis Egea-Jimenez, Frédérique Lembo, Joanna Fares, Sofie Meeussen, Sebastian Kügler, Anton Roebroek, Guido David, Pascale Zimmermann
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Exosomal transfers represent an important mode of intercellular communication. Syntenin is a small scaffold protein that, when binding ALIX, can direct endocytosed syndecans and syndecan cargo to budding endosomal membranes, supporting the f
Externí odkaz:
https://doaj.org/article/5818175db7fd4b9fba6c41d314e2d576
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 9, Pp 1554-1560 (2018)
Extracellular vesicles released by viable cells (exosomes and microvesicles) have emerged as important organelles supporting cell-cell communication. Because of their potential therapeutic significance, important efforts are being made toward charact
Externí odkaz:
https://doaj.org/article/acd5990627ba400a85b5e03ad733a9b3
Autor:
Antonio Luis Egea-Jimenez, Rodrigo Gallardo, Abel Garcia-Pino, Ylva Ivarsson, Anna Maria Wawrzyniak, Rudra Kashyap, Remy Loris, Joost Schymkowitz, Frederic Rousseau, Pascale Zimmermann
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
PDZ domain-containing proteins are known to function as intracellular scaffolds. Here, Egea-Jimenez et al. report the structure of the tandem PDZ domains of syntenin in complex with a Frizzled 7 peptide and PIP2, show that the ligands bind to synteni
Externí odkaz:
https://doaj.org/article/6a135f7cced44db1b5f72b08dd72540d
Autor:
Juan C. Gómez-Fernández, Emilio M. Serrano-López, Senena Corbalán-García, David López-Martínez, Antonio Luis Egea-Jimenez
Publikováno v:
International Journal of Biological Macromolecules. 185:377-389
PKCe is highly expressed in mast cells and plays a fundamental role in the antigen-triggered activation of the allergic reaction. Although its regulation by diacylglycerols has been described, its regulation by acidic phospholipids and how this regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0493413cb44117f3d9d8e699e4422050
https://doi.org/10.1016/j.ijbiomac.2021.06.019
https://doi.org/10.1016/j.ijbiomac.2021.06.019
Autor:
Pascale Zimmermann, Frédérique Lembo, Joanna Fares, Rudra Kashyap, Sebastian Kügler, Sofie Meeussen, Marielle Balzano, Kathleen Lambaerts, Anton J.M. Roebroek, Benoit Lechat, Antonio Luis Egea-Jimenez, Guido David
Publikováno v:
Scientific Reports
Scientific Reports, 2021, 11 (1), ⟨10.1038/s41598-021-81697-4⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, Nature Publishing Group, 2021, 11 (1), ⟨10.1038/s41598-021-81697-4⟩
Scientific Reports, 2021, 11 (1), ⟨10.1038/s41598-021-81697-4⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, Nature Publishing Group, 2021, 11 (1), ⟨10.1038/s41598-021-81697-4⟩
Exosomal transfers represent an important mode of intercellular communication. Syntenin is a small scaffold protein that, when binding ALIX, can direct endocytosed syndecans and syndecan cargo to budding endosomal membranes, supporting the formation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06cca585bc051dc749108a6fc80248ed
https://hal-amu.archives-ouvertes.fr/hal-03152171
https://hal-amu.archives-ouvertes.fr/hal-03152171
Autor:
Philippe Roche, Xavier Morelli, Manon Garcia, Fatiha Benmansour, Raphael Leblanc, Laurent Hoffer, Antonio Luis Egea-Jimenez, Carine Derviaux, Mikael Feracci, Pascale Zimmermann, Karine Barral
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, 2021, 223, pp.113601. ⟨10.1016/j.ejmech.2021.113601⟩
European Journal of Medicinal Chemistry, Elsevier, 2021, 223, pp.113601. ⟨10.1016/j.ejmech.2021.113601⟩
European Journal of Medicinal Chemistry, 2021, 223, pp.113601. ⟨10.1016/j.ejmech.2021.113601⟩
European Journal of Medicinal Chemistry, Elsevier, 2021, 223, pp.113601. ⟨10.1016/j.ejmech.2021.113601⟩
Syntenin stimulates exosome production and its expression is upregulated in many cancers and implicated in the spread of metastatic tumor. These effects are supported by syntenin PDZ domains interacting with syndecans. We therefore aimed to develop,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43013ddd9d4672c25efc8990391d57d8
https://hal.science/hal-03379016/file/EJMCh_Barral_2021_27052021.pdf
https://hal.science/hal-03379016/file/EJMCh_Barral_2021_27052021.pdf
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2256
Surface plasmon resonance (SPR)/BIAcore technology enables the characterization of molecular interactions, including determination of affinities and kinetics. In BIAcore, one of the interaction partners (the ligand) is immobilized on a chip and the o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::98fd2589c7ca3dbbecea8bc8ebc30189
https://pubmed.ncbi.nlm.nih.gov/34014517
https://pubmed.ncbi.nlm.nih.gov/34014517
Publikováno v:
Methods in Molecular Biology ISBN: 9781071611654
PDZ Mediated Interactions
PDZ Mediated Interactions, 2256, Springer US, pp.75-87, 2021, Methods in Molecular Biology, ⟨10.1007/978-1-0716-1166-1_5⟩
PDZ Mediated Interactions
PDZ Mediated Interactions, 2256, Springer US, pp.75-87, 2021, Methods in Molecular Biology, ⟨10.1007/978-1-0716-1166-1_5⟩
Surface plasmon resonance (SPR)/BIAcore technology enables the characterization of molecular interactions, including determination of affinities and kinetics. In BIAcore, one of the interaction partners (the ligand) is immobilized on a chip and the o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0709499b54134d6770d5f1c2e5f16115
https://doi.org/10.1007/978-1-0716-1166-1_5
https://doi.org/10.1007/978-1-0716-1166-1_5
Autor:
Rudra Kashyap, Karine Barral, Pascale Zimmermann, M. Platonov, Stephane Betzi, Laurent Hoffer, Carine Derviaux, Philippe Roche, Antonio Luis Egea-Jimenez, Rania Ghossoub, Mikael Feracci, M. Garcia, D. Kovalskyy, Raphael Leblanc, Xavier Morelli
Publikováno v:
Journal of Extracellular Vesicles
Journal of Extracellular Vesicles, Taylor & Francis, 2020, 10 (2), ⟨10.1002/jev2.12039⟩
Journal of Extracellular Vesicles, 2020, 10 (2), ⟨10.1002/jev2.12039⟩
'Journal of Extracellular Vesicles ', vol: 10, pages: e12039-1-e12039-17 (2020)
Journal of Extracellular Vesicles, Taylor & Francis, 2020, 10 (2), ⟨10.1002/jev2.12039⟩
Journal of Extracellular Vesicles, 2020, 10 (2), ⟨10.1002/jev2.12039⟩
'Journal of Extracellular Vesicles ', vol: 10, pages: e12039-1-e12039-17 (2020)
Exosomes support cell-to-cell communication in physiology and disease, including cancer. We currently lack tools, such as small chemicals, capable of modifying exosome composition and activity in a specific manner. Building on our previous understand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5734c60859249892f7107ad924881fde
https://hal-amu.archives-ouvertes.fr/hal-03152593
https://hal-amu.archives-ouvertes.fr/hal-03152593
Autor:
Guido David, Castro-Cruz M, Antonio Luis Egea-Jimenez, Stéphane Audebert, Luc Camoin, Pascale Zimmermann, Jean-Paul Borg
It is important to understand the biogenesis of exosomes, extracellular vesicles of endosomal origin controlling cell-to-cell communication. We previously reported that Phospholipase D2 (PLD2) supports late endosome (LE) budding and the biogenesis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c100d2af6afb0fd2248c5008b3de4246
https://doi.org/10.1101/2020.11.25.398396
https://doi.org/10.1101/2020.11.25.398396