Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Antonio Lax"'
Autor:
Antonio Lax, Fernando Soler, Maria Josefa Fernandez del Palacio, Silvia Pascual-Oliver, Miriam Ruiz Ballester, Jose Javier Fuster, Domingo Pascual-Figal, Maria del Carmen Asensio-Lopez
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 704-720 (2023)
Clinical use of doxorubicin (Dox), an anthracycline with potent anti-tumor effects, is limited because of its highly chemotherapy-induced cardiotoxicity (CIC). After myocardial infarction (MI), we have recently identified Yin Yang-1 (YY1) and histone
Externí odkaz:
https://doaj.org/article/7f5ddf751718429e8e8d49fae8e7e802
Autor:
Maria Carmen Asensio-Lopez, Yassine Sassi, Fernando Soler, Maria Josefa Fernandez del Palacio, Domingo Pascual-Figal, Antonio Lax
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Left ventricular remodeling following myocardial infarction (MI) is related to adverse outcome. It has been shown that an up-regulation of plasma soluble ST2 (sST2) levels are associated with lower pre-discharge left ventricular (LV) ejectio
Externí odkaz:
https://doaj.org/article/a73778c63e9d495c8bf2630519de6f06
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/d1a8d37f86d04e60aa245fcd3afe3e21
Autor:
Oriol Iborra-Egea, MSc, Evelyn Santiago-Vacas, MD, Salva R. Yurista, MD, Josep Lupón, MD, PhD, Milton Packer, MD, Stephane Heymans, MD, Faiez Zannad, MD, Javed Butler, MD, Domingo Pascual-Figal, MD, Antonio Lax, PhD, Julio Núñez, MD, PhD, Rudolf A. de Boer, MD, PhD, Antoni Bayés-Genís, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 7, Pp 831-840 (2019)
Summary: The mechanism of action of empagliflozin in heart failure with reduced ejection fraction (HFrEF) was deciphered using deep learning in silico analyses together with in vivo validation. The most robust mechanism of action involved the sodium-
Externí odkaz:
https://doaj.org/article/13afc25ce0834e1783d290a10c5de95e
Autor:
Maria del Carmen Asensio Lopez, Antonio Lax, Alvaro Hernandez Vicente, Elena Saura Guillen, Antonio Hernandez-Martinez, Maria Josefa Fernandez del Palacio, Antoni Bayes-Genis, Domingo A. Pascual Figal
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/d7ab907b9e24426b99920de473b0d348
Autor:
Mari C Asensio-López, Fernando Soler, Domingo Pascual-Figal, Francisco Fernández-Belda, Antonio Lax
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172803 (2017)
The primary cardiotoxic action of doxorubicin when used as antitumor drug is attributed to the generation of reactive oxygen species (ROS) therefore effective cardioprotection therapies are needed. In this sense, the antianginal drug nicorandil has b
Externí odkaz:
https://doaj.org/article/fd25acc393874d42b42f73fa35613e46
Autor:
Donatella Del Sindaco, Maria Denitza Tinti, Giovanni Pulignano, Stefano Tolone, Giovanni Minardi, Massimo Uguccioni, Antonio Lax
Publikováno v:
Monaldi Archives for Chest Disease, Vol 84, Iss 1-2 (2016)
In the setting of heart failure (HF) pharmacotherapy demonstrates a quantifiable improvement in exercise tolerance also in HF with preserved ejection fraction (HFpEF). For patients with HFpEF, often older, with higher prevalence of hypertension, diab
Externí odkaz:
https://doaj.org/article/d40e6abcfb784ef9ad57a4d967f37686
Autor:
Giovanni Pulignano, Maria Denitza Tinti, Donatella Del Sindaco, Stefano Tolone, Giovanni Minardi, Antonio Lax, Massimo Uguccioni
Publikováno v:
Monaldi Archives for Chest Disease, Vol 84, Iss 1-2 (2016)
In heart failure (HF), cardiac rehabilitation (CR) may reduce decompensations, hospitalization, and ultimately mortality in long term. Many studies over the past decade have demonstrated that aerobic exercise training is effective and safe in stable
Externí odkaz:
https://doaj.org/article/ea19aec488b846d7bd5bb9947d7aceb7
Autor:
Giovanni Pulignano, Donatella Del Sindaco, Maria Denitza Tinti, Stefano Tolone, Giovanni Minardi, Antonio Lax, Massimo Uguccioni
Publikováno v:
Heart International, Vol 11, Iss 1, Pp 0-0 (2016)
BackgroundAtrial fibrillation (AF) and heart failure (HF), two problems of growing prevalence as a consequence of the ageing population, are associated with high morbidity, mortality, and healthcare costs. AF and HF also share common risk factors and
Externí odkaz:
https://doaj.org/article/30dd28ce2c22497fb5dd95fb7ca1c5eb
Publikováno v:
Revista Española de Cardiología (English Edition).