Zobrazeno 1 - 10
of 142
pro vyhledávání: '"Antonio LEONARDI"'
Autor:
Suzanna M. Storms, Antonio Leonardi-Cattolica, Tara Prezioso, Csaba Varga, Leyi Wang, James Lowe
Publikováno v:
Frontiers in Veterinary Science, Vol 11 (2024)
IntroductionInfluenza A virus in swine (IAV-S) is common in the United States commercial swine population and has the potential for zoonotic transmission.ObjectiveTo elucidate influenza shedding the domestic pig population, we evaluated two commercia
Externí odkaz:
https://doaj.org/article/16868c6c46284d8ba4cea69c316f010d
Autor:
Mijung Yun, Naemi Ditlevsen Regen, Yuvicza Anchondo, Kelly Eddinger, Shelle Malkmus, Steven W. Roberts, Elisabetta Donati, Antonio Leonardi, Tony L. Yaksh
Publikováno v:
PAIN Reports, Vol 9, Iss 5, p e1168 (2024)
Abstract. Introduction:. We explored in mice, the analgesic, tolerance, dependency, and rewarding effects of systemic acetaminophen (APAP). Methods:. Studies employed adult mice (C57Bl6). (1) Intraplantar formalin flinching + post formalin allodynia.
Externí odkaz:
https://doaj.org/article/5cd7774dfe4a4eab914b47127b42219d
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 15, p 8448 (2024)
Therapy-induced senescence (TIS) represents a major cellular response to anticancer treatments. Both malignant and non-malignant cells in the tumor microenvironment undergo TIS and may be harmful for cancer patients since TIS cells develop a senescen
Externí odkaz:
https://doaj.org/article/ade99266b1844614b03c5c97de9ce4ba
Autor:
Jwala P. Sivaccumar, Emanuela Iaccarino, Angela Oliver, Maria Cantile, Pierpaolo Olimpieri, Antonio Leonardi, Menotti Ruvo, Annamaria Sandomenico
Publikováno v:
Pharmaceuticals, Vol 16, Iss 8, p 1130 (2023)
Drug development in recent years is increasingly focused on developing personalized treatments based on blocking molecules selective for therapeutic targets specifically present in individual patients. In this perspective, the specificity of therapeu
Externí odkaz:
https://doaj.org/article/3af5e9b380eb4d94a97cfec3cd903d04
Publikováno v:
Biology, Vol 12, Iss 7, p 989 (2023)
Iron participates in a number of biological processes and plays a crucial role in cellular homeostasis. Alterations in iron metabolism are considered hallmarks of cancer and drivers of aggressive behaviors, such as uncontrolled proliferation, resista
Externí odkaz:
https://doaj.org/article/b19a3fe3e0714ece98f23a1acc1fdbc9
Autor:
Valeria Caturano, Barbara Manti, Fortunata Carbone, Vito Alessandro Lasorsa, Roberta Colicchio, Mario Capasso, Antonio Leonardi, Giuseppe Matarese, Tommaso Russo, Paola Salvatore
Publikováno v:
BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-4 (2021)
Abstract Background The SARS-CoV-2 infection has emerged as a rapidly spreading infection. Today it is relatively easy to isolate Covid-19 symptomatic cases, while remains problematic to control the disease spread by infected but symptom-free individ
Externí odkaz:
https://doaj.org/article/ab3126954c224ee791deeebb84e67063
Autor:
Rosa Merlo, Diego Caprioglio, Michele Cillo, Anna Valenti, Rosanna Mattossovich, Castrese Morrone, Alberto Massarotti, Franca Rossi, Riccardo Miggiano, Antonio Leonardi, Alberto Minassi, Giuseppe Perugino
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 85-97 (2021)
SNAP-tag® is a powerful technology for the labelling of protein/enzymes by using benzyl-guanine (BG) derivatives as substrates. Although commercially available or ad hoc produced, their synthesis and purification are necessary, increasing time and c
Externí odkaz:
https://doaj.org/article/e8b45e7cf72a457c9492eda4510feb35
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2337 (2023)
In this review we focus on the role of glutamine in control of cancer stem cell (CSC) fate. We first provide an overview of glutamine metabolism, and then summarize relevant studies investigating how glutamine metabolism modulates the CSC compartment
Externí odkaz:
https://doaj.org/article/12d1a60e685147bd8d06ac72442b711f
Autor:
Laura Tornatore, Daria Capece, Daniel D'Andrea, Federica Begalli, Daniela Verzella, Jason Bennett, Gary Acton, Elizabeth A. Campbell, James Kelly, Michael Tarbit, Nigel Adams, Selina Bannoo, Antonio Leonardi, Annamaria Sandomenico, Domenico Raimondo, Menotti Ruvo, Angela Chambery, Metod Oblak, Magda J. Al-Obaidi, Richard S. Kaczmarski, Ian Gabriel, Heather E. Oakervee, Martin F. Kaiser, Ashutosh Wechalekar, Reuben Benjamin, Jane F. Apperley, Holger W. Auner, Guido Franzoso
Publikováno v:
Toxicology Reports, Vol 6, Iss , Pp 369-379 (2019)
Aberrant NF-κB activity drives oncogenesis and cell survival in multiple myeloma (MM) and many other cancers. However, despite an aggressive effort by the pharmaceutical industry over the past 30 years, no specific IκBα kinase (IKK)β/NF-κB inhib
Externí odkaz:
https://doaj.org/article/2bef177c9ad24c388d8e263481c9368e
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12333 (2021)
The signaling network between cancer and stromal cells plays a crucial role in tumor microenvironment. The fate of tumor progression mainly depends on the huge amount of information that these cell populations exchange from the onset of neoplastic tr
Externí odkaz:
https://doaj.org/article/f0b6c2afef364de7a9218ec9cd0b8c23