Validation and functional characterization of GWAS-identified variants for chronic lymphocytic leukemia: a CRuCIAL study

Autor: Paloma García-Martín, Ana Moñiz Díez, José Manuel Sánchez Maldonado, Antonio José Cabrera Serrano, Rob ter Horst, Yolanda Benavente, Stefano Landi, Angelica Macauda, Alyssa Clay-Gilmour, Francisca Hernández-Mohedo, Yasmeen Niazi, Pedro González-Sierra, Blanca Espinet, Juan José Rodríguez-Sevilla, Rossana Maffei, Gonzalo Blanco, Matteo Giaccherini, Anna Puiggros, James Cerhan, Roberto Marasca, Marisa Cañadas-Garre, Miguel Ángel López-Nevot, Tzu Chen-Liang, Hauke Thomsen, Irene Gámez, Víctor Moreno, Rafael Marcos-Gragera, María García-Álvarez, Javier Llorca, Andrés Jerez, Sonja Berndt, Aleksandra Butrym, Aaron D. Norman, Delphine Casabonne, Mario Luppi, Susan L. Slager, Kari Hemminki, Yang Li, Miguel Alcoceba, Daniele Campa, Federico Canzian, Silvia de Sanjosé, Asta Försti, Mihai G. Netea, Manuel Jurado, Juan Sainz

Publikováno v: Blood Cancer Journal, Vol 12, Iss 5, Pp 1-6 (2022)

Externí odkaz: https://doaj.org/article/d236457e4d52430a8d875808f2daf6c6

Polymorphisms within the TNFSF4 and MAPKAPK2 Loci Influence the Risk of Developing Invasive Aspergillosis: A Two-Stage Case Control Study in the Context of the aspBIOmics Consortium

Autor: Jose Manuel Sánchez-Maldonado, Ana Moñiz-Díez, Rob ter Horst, Daniele Campa, Antonio José Cabrera-Serrano, Manuel Martínez-Bueno, María del Pilar Garrido-Collado, Francisca Hernández-Mohedo, Laura Fernández-Puerta, Miguel Ángel López-Nevot, Cristina Cunha, Pedro Antonio González-Sierra, Jan Springer, Michaela Lackner, Laura Alcazar-Fuoli, Luana Fianchi, José María Aguado, Livio Pagano, Elisa López-Fernández, Esther Clavero, Leonardo Potenza, Mario Luppi, Lucia Moratalla, Carlos Solano, Antonio Sampedro, Manuel Cuenca-Estrella, Cornelia Lass-Flörl, PCRAGA Study Group, Federico Canzian, Juergen Loeffler, Yang Li, Hermann Einsele, Mihai G. Netea, Lourdes Vázquez, Agostinho Carvalho, Manuel Jurado, Juan Sainz

Publikováno v: Journal of Fungi, Vol 7, Iss 1, p 4 (2020)

Here, we assessed whether 36 single nucleotide polymorphisms (SNPs) within the TNFSF4 and MAPKAPK2 loci influence the risk of developing invasive aspergillosis (IA). We conducted a two-stage case control study including 911 high-risk patients diagnos

Externí odkaz: https://doaj.org/article/7ffd7f2e74154c68aeb332e792fad767

Do GWAS-Identified Risk Variants for Chronic Lymphocytic Leukemia Influence Overall Patient Survival and Disease Progression?

Autor: Antonio José Cabrera-Serrano, José Manuel Sánchez-Maldonado, Rob ter Horst, Angelica Macauda, Paloma García-Martín, Yolanda Benavente, Stefano Landi, Alyssa Clay-Gilmour, Yasmeen Niazi, Blanca Espinet, Juan José Rodríguez-Sevilla, Eva María Pérez, Rossana Maffei, Gonzalo Blanco, Matteo Giaccherini, James R. Cerhan, Roberto Marasca, Miguel Ángel López-Nevot, Tzu Chen-Liang, Hauke Thomsen, Irene Gámez, Daniele Campa, Víctor Moreno, Silvia de Sanjosé, Rafael Marcos-Gragera, María García-Álvarez, Trinidad Dierssen-Sotos, Andrés Jerez, Aleksandra Butrym, Aaron D. Norman, Mario Luppi, Susan L. Slager, Kari Hemminki, Yang Li, Sonja I. Berndt, Delphine Casabonne, Miguel Alcoceba, Anna Puiggros, Mihai G. Netea, Asta Försti, Federico Canzian, Juan Sainz

Publikováno v: International Journal of Molecular Sciences, 24, 9
International Journal of Molecular Sciences, 24

Chronic lymphocytic leukemia (CLL) is the most common leukemia among adults worldwide. Although genome-wide association studies (GWAS) have uncovered the germline genetic component underlying CLL susceptibility, the potential use of GWAS-identified r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00bc47a6497d007d68f5c54e941e1ca3
https://hdl.handle.net/2066/292738

Polymorphisms within the TNFSF4 and mapkapk2 loci influence the risk of developing invasive aspergillosis: A two-stage case control study in the context of the aspbiomics consortium

Autor: Juan Sainz, Pedro Antonio González-Sierra, Laura Fernández-Puerta, Francisca Hernández-Mohedo, Antonio José Cabrera-Serrano, Livio Pagano, Manuel Martínez-Bueno, Esther Clavero, Carlos Solano, Hermann Einsele, Luana Fianchi, Manuel Cuenca-Estrella, Yang Li, Antonio Sampedro, María Del Pilar Garrido-Collado, Rob ter Horst, Elisa López-Fernández, Lourdes Vázquez, Agostinho Carvalho, Leonardo Potenza, Mario Luppi, Juergen Loeffler, Manuel Jurado, Lucía Moratalla, Laura Alcazar-Fuoli, José María Aguado, Federico Canzian, Miguel A. López-Nevot, Michaela Lackner, Daniele Campa, Jose Manuel Sánchez-Maldonado, Jan Springer, Cornelia Lass-Flörl, Ana Moñiz-Díez, Cristina Cunha, Mihai G. Netea

Publikováno v: Digibug. Repositorio Institucional de la Universidad de Granada
instname
Journal of Fungi
Volume 7
Issue 1
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Journal of Fungi, 7, 1
Journal of Fungi, 7
Repisalud
Instituto de Salud Carlos III (ISCIII)
Journal of Fungi, Vol 7, Iss 4, p 4 (2021)

Here, we assessed whether 36 single nucleotide polymorphisms (SNPs) within the TNFSF4 and MAPKAPK2 loci influence the risk of developing invasive aspergillosis (IA). We conducted a twostage case control study including 911 high-risk patients diagnose

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3c0873e2d47c647a86557fcdf82a60f
http://hdl.handle.net/10807/176223

OP0017 VALIDATION OF GWAS-IDENTIFIED VARIANTS FOR ANTI-TNF DRUG RESPONSE IN RHEUMATOID ARTHRITIS: A META-ANALYSIS OF THREE LARGE COHORTS

Autor: João Eurico Fonseca, E. Collantes Estevez, Marieke J H Coenen, Jerzy Swierkot, Miguel A. López-Nevot, Juan Sainz, Signe Bek Sørensen, R. Ter Horst, Katarzyna Bogunia-Kubik, Jose Manuel Sánchez-Maldonado, Antonio José Cabrera-Serrano, Vibeke Andersen, R. Cáliz Cáliz, I. Filipescu, Ana Moñiz-Díez, S. De Vita, Helena Canhão, Pablo Conesa-Zamora, Yi Li, A.A. den Broeder, Luca Quartuccio, M. Á. Ferrer González, S. E. Hove Jaconsen, Eva Perez-Pampin, B. Glintborg, A. Escudero Contreras, Merete Lund Hetland, Mihai G. Netea

Publikováno v: Annals of the Rheumatic Diseases. 80:9.2-10

Background:The interplay between genetics and drug response in rheumatoid arthritis (RA) has shown that response to biologics varies between individuals and that a large proportion of patients show no clinical improvement (Plenge and Bridges, 2011).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::38af81e136e10465f19ff7b9cb4bad5d
https://doi.org/10.1136/annrheumdis-2021-eular.2248