Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Antonio Jordán-Pla"'
Autor:
Moran Kelbert, Antonio Jordán-Pla, Lola de Miguel-Jiménez, José García-Martínez, Michael Selitrennik, Adi Guterman, Noa Henig, Sander Granneman, José E Pérez-Ortín, Sebastián Chávez, Mordechai Choder
Publikováno v:
eLife, Vol 12 (2024)
To function effectively as an integrated system, the transcriptional and post-transcriptional machineries must communicate through mechanisms that are still poorly understood. Here, we focus on the zinc-finger Sfp1, known to regulate transcription of
Externí odkaz:
https://doaj.org/article/142d36e65ad542ed92936c9e6151ec17
Autor:
Ana Domingo-Muelas, Pere Duart-Abadia, Jose Manuel Morante-Redolat, Antonio Jordán-Pla, Germán Belenguer, Jaime Fabra-Beser, Lucía Paniagua-Herranz, Ana Pérez-Villalba, Adrián Álvarez-Varela, Francisco M. Barriga, Cristina Gil-Sanz, Felipe Ortega, Eduard Batlle, Isabel Fariñas
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Here the authors identify RNA-binding protein MEX3A as a post-transcriptional regulator of quiescence and differentiation signatures at critical transitions along the murine subependymal neurogenic lineage
Externí odkaz:
https://doaj.org/article/8e6b32c2f978416f911aa4d6ff712bbe
Autor:
Laura García-Corzo, Isabel Calatayud-Baselga, Lucía Casares-Crespo, Carlos Mora-Martínez, Juan Julián Escribano-Saiz, Rafael Hortigüela, Andrea Asenjo-Martínez, Antonio Jordán-Pla, Stefano Ercoli, Nuria Flames, Victoria López-Alonso, Marçal Vilar, Helena Mira
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Stem cells in adult mammalian tissues are held in a reversible resting state, known as quiescence, for prolonged periods of time. Recent studies have greatly increased our understanding of the epigenetic and transcriptional landscapes that underlie s
Externí odkaz:
https://doaj.org/article/5785089cc2c14e5c91310156b970eccd
Autor:
Cristina Bono, Paula Guerrero, Antonio Jordán-Pla, Ana Erades, Nathan Salomonis, H. Leighton Grimes, M. Luisa Gil, Alberto Yáñez
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
More mechanistic studies are needed to reveal the hidden details of in vivo-induced trained immunity. Here, using a Candida albicans live vaccine mouse model we show that vaccination protects mice against a secondary infection and increases the numbe
Externí odkaz:
https://doaj.org/article/1d2e461a4ddb46ada610f952c16b52bc
Autor:
Anna Lozano-Ureña, Esteban Jiménez-Villalba, Alejandro Pinedo-Serrano, Antonio Jordán-Pla, Martina Kirstein, Sacri R. Ferrón
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
In human glioblastoma (GBM), the presence of a small population of cells with stem cell characteristics, the glioma stem cells (GSCs), has been described. These cells have GBM potential and are responsible for the origin of the tumors. However, wheth
Externí odkaz:
https://doaj.org/article/837ff70ac14a448891d86c0a6dd2c738
SWI/SNF regulates half of its targets without the need of ATP-driven nucleosome remodeling by Brahma
Autor:
Antonio Jordán-Pla, Simei Yu, Johan Waldholm, Thomas Källman, Ann-Kristin Östlund Farrants, Neus Visa
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-12 (2018)
Abstract Background Brahma (BRM) is the only catalytic subunit of the SWI/SNF chromatin-remodeling complex of Drosophila melanogaster. The function of SWI/SNF in transcription has long been attributed to its ability to remodel nucleosomes, which requ
Externí odkaz:
https://doaj.org/article/5c8079d447074015b00608a273a09079
Autor:
Gabriel Gutiérrez, Gonzalo Millán-Zambrano, Daniel A. Medina, Antonio Jordán-Pla, José E. Pérez-Ortín, Xenia Peñate, Sebastián Chávez
Publikováno v:
Epigenetics & Chromatin, Vol 10, Iss 1, Pp 1-22 (2017)
Abstract Background TFIIS stimulates RNA cleavage by RNA polymerase II and promotes the resolution of backtracking events. TFIIS acts in the chromatin context, but its contribution to the chromatin landscape has not yet been investigated. Co-transcri
Externí odkaz:
https://doaj.org/article/a75964c5818b48a08a08fdeaceb7a80e
Autor:
Cristina Bono, Paula Guerrero, Ana Erades, Antonio Jordán-Pla, Alberto Yáñez, María Luisa Gil
Publikováno v:
Stem Cells. 40:949-962
During an infection, hematopoiesis is altered to increase the output of mature myeloid cells to fight off the pathogen. Despite convincing evidence that hematopoietic stem and progenitor cells (HSPCs) can sense pathogens directly, more mechanistic st
Autor:
Jordi Planells, Antonio Jordán-Pla, Shruti Jain, Juan José Guadalupe, Estelle Proux-Wera, Anne von Euler, Vicent Pelechano, Neus Visa
Chromatin-associated RNAs (caRNAs) modulate chromatin organization and function. The RNA exosome degrades different types of nuclear transcripts, but its role in chromatin has not been addressed. Here we have usedDrosophila melanogasterS2 cells as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49647616a4db4c95e0d0ed83220a0df0
https://doi.org/10.1101/2023.04.10.536209
https://doi.org/10.1101/2023.04.10.536209
Autor:
Ana Domingo-Muelas, Jose Manuel Morante-Redolat, Verónica Moncho-Amor, Antonio Jordán-Pla, Ana Pérez-Villalba, Pau Carrillo-Barberà, Germán Belenguer, Eva Porlan, Martina Kirstein, Oriol Bachs, Sacri R. Ferrón, Robin Lovell-Badge, Isabel Fariñas
Cell differentiation involves profound changes in global gene expression that often have to occur in coordination with cell cycle exit. Because cyclin-dependent kinase inhibitor p27 reportedly regulates proliferation of neural progenitor cells in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9ff69be4fea11075862b57f67de1243
https://hdl.handle.net/10486/706785
https://hdl.handle.net/10486/706785