Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Antonio J. Pagán"'
Autor:
Kevin K Takaki, Francisco J Roca, Gabriele Schramm, Ruud H P Wilbers, Wannaporn Ittiprasert, Paul J Brindley, Gabriel Rinaldi, Matthew Berriman, Lalita Ramakrishnan, Antonio J Pagán
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 1, p e0008814 (2021)
Infections by schistosomes result in granulomatous lesions around parasite eggs entrapped within the host tissues. The host and parasite determinants of the Schistosoma mansoni egg-induced granulomatous response are areas of active investigation. Som
Externí odkaz:
https://doaj.org/article/61da5d83500e4279a2033dc12ad60ad2
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0233252 (2020)
Phthiocerol dimycocerosates (PDIMs) are a class of mycobacterial lipids that promote virulence in Mycobacterium tuberculosis and Mycobacterium marinum. It has recently been shown that PDIMs work in concert with the M. tuberculosis Type VII secretion
Externí odkaz:
https://doaj.org/article/897e218d943c4c9781e5587fde7e344e
Autor:
Antonio J. Pagán, Lauren J. Lee, Joy Edwards-Hicks, Cecilia B. Moens, David M. Tobin, Elisabeth M. Busch-Nentwich, Erika L. Pearce, Lalita Ramakrishnan
Publikováno v:
Cell
Necrosis of macrophages in the tuberculous granuloma represents a major pathogenic event in tuberculosis. Through a zebrafish forward genetic screen, we identified the mTOR kinase, a master regulator of metabolism, as an early host resistance factor
Autor:
Nathan C Peters, Antonio J Pagán, Phillip G Lawyer, Timothy W Hand, Eric Henrique Roma, Lisa W Stamper, Audrey Romano, David L Sacks
Publikováno v:
PLoS Pathogens, Vol 10, Iss 12, p e1004538 (2014)
In contrast to the ability of long-lived CD8(+) memory T cells to mediate protection against systemic viral infections, the relationship between CD4(+) T cell memory and acquired resistance against infectious pathogens remains poorly defined. This is
Externí odkaz:
https://doaj.org/article/a91e9808085c422a8c11adf6e270571a
Autor:
Mark Troll, Antonio J. Pagán, Nguyen Duc Bang, Rajan Troll, Lalita Ramakrishnan, David M. Tobin, Paul H. Edelstein, Roger Sewell, Nguyen Hoan Phu, Nguyen Thuy Thuong Thuong, Guy E. Thwaites, Laura Whitworth, Francisco J. Roca
Publikováno v:
Proc Natl Acad Sci U S A
Adjunctive treatment with antiinflammatory corticosteroids like dexamethasone increases survival in tuberculosis meningitis. Dexamethasone responsiveness associates with a C/T variant in Leukotriene A4 Hydrolase (LTA4H), which regulates expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d37878b23fe82738b7f4ccbf45b273d7
Autor:
Antonio J Pagán, Lauren J Lee, Joy Edwards-Hicks, Cecilia B Moens, David M Tobin, Erika L Pearce, Elisabeth Busch-Nentwich, Lalita Ramakrishnan
Publikováno v:
The Journal of Immunology. 208:163.32-163.32
Necrosis of macrophages in the tuberculous granuloma represents a major pathogenic event in tuberculosis. Through a zebrafish forward genetic screen, we identified the mTOR kinase, a master regulator of metabolism, as an early host resistance factor
Publikováno v:
Cell Host & Microbe
Summary Schistosome eggs provoke the formation of granulomas, organized immune aggregates, around them. For the host, the granulomatous response can be both protective and pathological. Granulomas are also postulated to facilitate egg extrusion throu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc2303eac0ca882483e69c741bee1060
https://www.repository.cam.ac.uk/handle/1810/317095
https://www.repository.cam.ac.uk/handle/1810/317095
Autor:
Antonio J. Pagán, Paul J. Brindley, Kevin K. Takaki, Gabriele Schramm, Ruud H. P. Wilbers, Francisco J. Roca, Matthew Berriman, Wannaporn Ittiprasert, Lalita Ramakrishnan, Gabriel Rinaldi
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, 15(1), 1-12
PLoS Neglected Tropical Diseases 15 (2021) 1
PLoS Neglected Tropical Diseases, Vol 15, Iss 1, p e0008814 (2021)
PLoS Neglected Tropical Diseases, 15(1), 1-12
PLoS Neglected Tropical Diseases 15 (2021) 1
PLoS Neglected Tropical Diseases, Vol 15, Iss 1, p e0008814 (2021)
Infections by schistosomes result in granulomatous lesions around parasite eggs entrapped within the host tissues. The host and parasite determinants of the Schistosoma mansoni egg-induced granulomatous response are areas of active investigation. Som
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff9eee3f29d96193eaa62ad2ac7296c0
https://www.repository.cam.ac.uk/handle/1810/317174
https://www.repository.cam.ac.uk/handle/1810/317174
Autor:
Francisco J. Roca, Lalita Ramakrishnan, Antonio J. Pagán, Roger Sewell, Paul H. Edelstein, Mark Troll, Nguyen Thuy Thuong Thuong, Laura Whitworth, David M. Tobin, Nguyen Duc Bang, Rajan Troll, Guy E. Thwaites, Nguyen Hoan Phu
Adjunctive treatment with anti-inflammatory corticosteroids like dexamethasone increases survival in tuberculosis meningitis. Dexamethasone responsiveness associates with a C/T variant inLeukotriene A4 Hydrolase (LTA4H), which regulates expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42be47575ceb2612516bbe0a2b5d860f
https://doi.org/10.1101/2020.11.23.394437
https://doi.org/10.1101/2020.11.23.394437
Autor:
Gabriele Schramm, Paul J. Brindley, Kevin K. Takaki, Ruud H. P. Wilbers, Matthew Berriman, Wannaporn Ittiprasert, Lalita Ramakrishnan, Francisco J. Roca, Gabriel Rinaldi, Antonio J. Pagán
Infections by schistosomes result in granulomatous lesions around parasite eggs entrapped within the host tissues. The host and parasite determinants of theSchistosoma mansoniegg-induced granulomatous response are areas of active investigation. Some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::859d155cd9362f087f2b0382349d9d6a
https://doi.org/10.1101/2020.09.29.318105
https://doi.org/10.1101/2020.09.29.318105