Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Antonio J. Ferruelo"'
Autor:
Javier Martínez-Botas, Miguel A. Lasunción, Antonio J. Ferruelo, Diego Gómez-Coronado, Carlos Fernández-Hernando, Sara Rodríguez-Acebes, Paloma de la Cueva
Publikováno v:
Biochemical and Biophysical Research Communications. 377:484-488
We addressed the ability of native, oxidized and acetylated low-density lipoproteins (nLDL, oxLDL and acLDL, respectively) and desmosterol to act as sources of sterol for the proliferation of J774A.1 macrophages. Treatment with 0.5 microM lovastatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae0c32a12ef6a95db3a59d71f0bbef2b
https://doi.org/10.1016/j.bbrc.2008.09.140
https://doi.org/10.1016/j.bbrc.2008.09.140
Autor:
Antonio J. Ferruelo, Carlos Fernández, Yajaira Suárez, Diego Gómez-Coronado, Miguel A. Lasunción
Publikováno v:
Biochemical Journal. 366:109-119
Dietary phytosterols are cholesterol-lowering agents that interfere with the intestinal absorption of cholesterol. In the present study, we have studied their effects on cholesterol biosynthesis in human cells, particularly in the sterol-conversion p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94b94496531d87b581afc526594eb1fe
https://doi.org/10.1042/bj20011777
https://doi.org/10.1042/bj20011777
Autor:
Miguel A. Vega, Antonio J. Ferruelo, Miguel Martín, Diego Gómez-Coronado, Miguel A. Lasunción, Beatriz Ledo, Carlos Fernández, Yajaira Suárez
Publikováno v:
European Journal of Biochemistry. 269:1761-1771
Cholesterol is essential for cell growth and division, but whether this is just a consequence of its use in membrane formation or whether it also elicits regulatory actions in cell cycle machinery remains to be established. Here, we report on the spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3dd741120d886e86d5f23ab2b636ac61
https://doi.org/10.1046/j.1432-1327.2002.02822.x
https://doi.org/10.1046/j.1432-1327.2002.02822.x
Autor:
Marı́a Teresa Montero, Yajaira Suárez, Joaquı́n Matilla, Diego Gómez-Coronado, Javier Martínez-Botas, Antonio J. Ferruelo, Osvaldo Hernández, Miguel A. Lasunción
Publikováno v:
Atherosclerosis. 153:303-313
T cells are prominent components of both early and late atherosclerotic lesions and the role of Th1/Th2 cells subsets in the evolution and rupture of the plaque is currently under investigation. Statins, which are inhibitors of 3-hydroxy-3-methylglut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f682371de4ebc3e7d0d0192fb0f98a1
https://doi.org/10.1016/s0021-9150(00)00417-2
https://doi.org/10.1016/s0021-9150(00)00417-2
Autor:
Diego Gómez-Coronado, Miguel A. Lasunción, Antonio J. Ferruelo, Yajaira Suárez, Javier Martínez-Botas
Publikováno v:
Biochimie. 80:887-894
To determine the role of cholesterol deprivation in cell proliferation and, eventually, in apoptosis, HL-60 promyelocytic cells were incubated in a cholesterol-depleted medium in the presence of SKF 104976, a specific inhibitor of lanosterol 14-alpha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e1b9d07a063fc40beadaa4f3b2b3bb0
https://doi.org/10.1016/s0300-9084(00)88884-7
https://doi.org/10.1016/s0300-9084(00)88884-7
Autor:
Sara Rodríguez-Acebes, Paloma de la Cueva, Robert B. Rawson, Carlos Fernández-Hernando, Javier Martínez-Botas, Antonio J. Ferruelo, Diego Gómez-Coronado, Miguel A. Lasunción
Publikováno v:
The Biochemical journal. 420(2)
Cholesterol homoeostasis is critical for cell viability and proliferation. The SREBP (sterol regulatory element-binding protein) pathway is crucial for the maintenance of cholesterol homoeostasis. This pathway is controlled by cholesterol and cholest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9edf32d4dcb2c16945d943c5e479d1b9
https://pubmed.ncbi.nlm.nih.gov/19426142
https://pubmed.ncbi.nlm.nih.gov/19426142
Autor:
Miguel A. Lasunción, Javier Martínez-Botas, Alberto Dávalos, Antonio J. Ferruelo, Yajaira Suárez, Carlos Fernández, Diego Gómez-Coronado
Publikováno v:
Cardiovascular research. 64(2)
Objective : To study the mechanism involved in the cholesterol-lowering activity of tamoxifen, an estrogen receptor (ER) modulator widely used in breast cancer therapy. Methods and results : We used MOLT-4 cells, which do not express estrogen recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1554c33ccab3286405b481ef4f2285b
https://pubmed.ncbi.nlm.nih.gov/15485695
https://pubmed.ncbi.nlm.nih.gov/15485695
Autor:
Yajaira, Suárez, Carlos, Fernández, Beatriz, Ledo, Antonio J, Ferruelo, Miguel, Martín, Miguel A, Vega, Diego, Gómez-Coronado, Miguel A, Lasunción
Publikováno v:
European journal of biochemistry. 269(6)
Cholesterol is essential for cell growth and division, but whether this is just a consequence of its use in membrane formation or whether it also elicits regulatory actions in cell cycle machinery remains to be established. Here, we report on the spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c4acb5dd18e74251afc4326e07d73a21
https://pubmed.ncbi.nlm.nih.gov/11895447
https://pubmed.ncbi.nlm.nih.gov/11895447
Autor:
Carlos Fernández, Miguel A. Lasunción, Diego Gómez-Coronado, Antonio J. Ferruelo, Yajaira Suárez, Javier Martínez-Botas
Publikováno v:
Biochimica et biophysica acta. 1532(3)
The mevalonate pathway is tightly linked to cell proliferation. The aim of the present study is to determine the relationship between the inhibition of this pathway by lovastatin and the cell cycle. HL-60 and MOLT-4 human cell lines were cultured in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12dd163245ddbcfb909a4a4f7d4663e6
https://pubmed.ncbi.nlm.nih.gov/11470239
https://pubmed.ncbi.nlm.nih.gov/11470239
Autor:
Sara Rodríguez‑Acebes, Paloma de la Cueva, Carlos Fernández‑Hernando, Antonio J. Ferruelo, Robert B. Rawson
Publikováno v:
Biochemical Journal; May2009, Vol. 420 Issue 2, p305-315, 11p