Zobrazeno 1 - 10
of 1 009
pro vyhledávání: '"Antonio Gutierrez"'
Autor:
Mercedes Salgueira, Marina Almenara, Antonio Gutierrez-Pizarraya, Lara Belmar, Pedro Jesús Labrador, Rosa Melero, María Luisa Serrano, José María Portolés, Alicia Molina, Esteban Poch, Natalia Ramos, María Jesús Lloret, Rocío Echarri, Raquel Díaz Mancebo, Diego Mauricio González-Lara, Jesús Emilio Sánchez, María José Soler
Publikováno v:
Nefrología, Vol 44, Iss 4, Pp 527-539 (2024)
Resumen: Antecedentes y objetivos: El desarrollo de lesión renal aguda (FRA) durante la hospitalización por SARS-Cov-2 se ha asociado a una elevada morbimortalidad. El Registro FRA-COVID SEN ha recogido datos de pacientes con este perfil durante lo
Externí odkaz:
https://doaj.org/article/072ef40525aa4283ad568e4dbad1b0d3
Autor:
José L. Mondaza-Hernandez, Nadia Hindi, Antonio Fernandez-Serra, Rafael Ramos, Ricardo Gonzalez-Cámpora, María Carmen Gómez-Mateo, Javier Martinez-Trufero, Javier Lavernia, Antonio Lopez-Pousa, Nuria Laínez, Jeronimo Martinez-Garcia, Claudia Valverde, María Ángeles Vaz-Salgado, Gabriel Garcia-Plaza, Isabel Marin-Borrero, Jaime Carrillo-Garcia, Marta Martin-Ruiz, Pablo Romero, Antonio Gutierrez, Jose A. López-Guerrero, David S. Moura, Javier Martin-Broto
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Background: Alveolar soft-part sarcoma (ASPS) is a rare tumor driven by the ASPSCR1-TFE3 fusion protein, with a propensity for metastasis. Prognostic factors remain poorly understood, and traditional chemotherapies are largely ineffective. Recent int
Externí odkaz:
https://doaj.org/article/a6bb78ace54b4bffac308c6bcc6f7d85
Autor:
Mariana Bastos‐Oreiro, Pau Abrisqueta, Antonio Gutierrez, Ana Jiménez Ubieto, Maria Poza, Paula Fernanez‐Caldas, María José LLacer, Sonia Gonzalez de Villambrosia, Raúl Córdoba, Alberto López, Elena Ceballos, Belen Navarro, Ana Muntañola, Eva Donato, Eva Diez‐Baeza, Lourdes Escoda, Hugo Luzardo, María José Peñarrubia, Daniel García Belmonte, Emilia Pardal, Claudia Lozada, Alejandro Martín García‐Sancho
Publikováno v:
HemaSphere, Vol 8, Iss 4, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/d8c7f322e8dd4cb4b2142be7e9abc2c2
Autor:
Javier Martin-Broto, Jeronimo Martinez-Garcia, David S. Moura, Andres Redondo, Antonio Gutierrez, Antonio Lopez-Pousa, Javier Martinez-Trufero, Isabel Sevilla, Roberto Diaz-Beveridge, Maria Pilar Solis-Hernandez, Amancio Carnero, Marco Perez, David Marcilla, Jesus Garcia-Foncillas, Pablo Romero, Javier Fernandez-Jara, Daniel Lopez-Lopez, Ivan Arribas, Nadia Hindi
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-10 (2023)
Abstract Cyclin-dependent kinases 4 and 6 (CDK4/6) inhibitors demonstrated activity in terms of progression-free survival (PFS) in advanced dedifferentiated liposarcoma (DD-LPS), a sarcoma with CDK4 amplification. CDK4 overexpression is by far more c
Externí odkaz:
https://doaj.org/article/0c66d90901d244e6922dd1f9ea0a3f1f
Autor:
Javier Martin-Broto, Claudia Valverde, Nadia Hindi, Bruno Vincenzi, Javier Martinez-Trufero, Giovanni Grignani, Antoine Italiano, Javier Lavernia, Ana Vallejo, Paolo Dei Tos, Francois Le Loarer, Ricardo Gonzalez-Campora, Rafael Ramos, Diana Hernández-Jover, Antonio Gutierrez, Cesar Serrano, Maria Monteagudo, Rocio Letón, Mercedes Robledo, David S. Moura, Marta Martin-Ruiz, Jose A. López-Guerrero, Julia Cruz, Antonio Fernandez-Serra, Jean-Yves Blay, Elena Fumagalli, Virginia Martinez-Marin
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-8 (2023)
Abstract Background Approximately 15% of adult GIST patients harbor tumors that are wild-type for KIT and PDGFRα genes (KP-wtGIST). These tumors usually have SDH deficiencies, exhibit a more indolent behavior and are resistant to imatinib. Underlyin
Externí odkaz:
https://doaj.org/article/da2ebd0056004ea28583248f6fd4476c
Autor:
Jaime Carrillo-García, Serena Lacerenza, Nadia Hindi, Irene Carrasco García, Gloria Marquina, Juana María Cano Cano, Javier Martínez Trufero, Alberto Rafael Sevillano Tripero, Tania Luis García, Manuel Jorge Cuesta Rioboo, David S. Moura, Marta Renshaw, Jose L. Mondaza-Hernández, Davide Di Lernia, Antonio Gutierrez, Javier Martin-Broto
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Background and objectives: Social distancing and quarantine implanted during the COVID-19 outbreak could have delayed the accession of oncologic patients to hospitals and treatments. This study analysed the management of sarcoma patients during this
Externí odkaz:
https://doaj.org/article/4176abcd3fc94b44bd8251892b02ec4b
Autor:
Javier Martin-Broto, Alicia Olarte-García, Ricardo Fernandéz-Rodríguez, Marta Ribeiro Ferreira, Irene Carrasco-García, Fernando Galvez-Montosa, Inmaculada Rincon-Perez, Javier Peinado-Serrano, Ignacio Azinovic, Laura Guzman-Gomez, Lurdes Salgado, Alberto Sevillano, Justo Ortega, Cristina Alvarez, Antonio Gutierrez, David S. Moura, Nadia Hindi
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Background and objectives: Dimensional response is an unmet need in second lines of advanced soft tissue sarcomas (STS). Indeed, the three approved drugs, pazopanib, trabectedin, and eribulin, achieved an overall response rate (ORR) of less than 10%.
Externí odkaz:
https://doaj.org/article/1475ef79f82c4873859ed0806a878ff3
Autor:
Antonio Gutierrez, Aser Alonso, Marta Garcia-Recio, Sandra Perez, Lucia Garcia-Maño, Jordi Martinez-Serra, Teresa Ros, Mercedes Garcia-Gasalla, Joana Ferrer, Oliver Vögler, Regina Alemany, Antonio Salar, Antonia Sampol, Leyre Bento
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe use of maintenance approaches with anti-CD20 monoclonal antibodies has improved the outcomes of B-cell indolent lymphomas but may lead to significant peripheral B-cell depletion. This depletion can potentially hinder the serological r
Externí odkaz:
https://doaj.org/article/2fc1ae4b861a4350a4c2a0a44db9516e
Autor:
Dimitris Bertsimas, Georgios Antonios Margonis, Seehanah Tang, Angelos Koulouras, Cristina R. Antonescu, Murray F. Brennan, Javier Martin-Broto, Piotr Rutkowski, Georgios Stasinos, Jane Wang, Emmanouil Pikoulis, Elzbieta Bylina, Pawel Sobczuk, Antonio Gutierrez, Bhumika Jadeja, William D. Tap, Ping Chi, Samuel Singer
Publikováno v:
EClinicalMedicine, Vol 64, Iss , Pp 102200- (2023)
Summary: Background: There are several models that predict the risk of recurrence following resection of localised, primary gastrointestinal stromal tumour (GIST). However, assessment of calibration is not always feasible and when performed, calibrat
Externí odkaz:
https://doaj.org/article/53e3b7f9ab6149689ef9632e7de90721
Autor:
Javier Martin-Broto, Andres Redondo, David S. Moura, Claudia Valverde, Jose Manuel Morales, Antonio Lopez-Pousa, Javier Martinez-Trufero, Antonio Gutierrez, Roberto Díaz-Beveridge, Pablo Luna, Virginia Martinez-Marin, David Marcilla, Ivan Arribas, Patricio Ledesma, Jose Antonio Lopez-Martin, Davide Di Lernia, Jorge Zamora, Nadia Hindi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
In patients with progressive and symptomatic desmoid fibromatosis (DF) treatment with chemotherapy is typically prolonged, while surgery carries a high risk of relapse. Here, the authors report the results of a phase II clinical trial of short-course
Externí odkaz:
https://doaj.org/article/fa55a5db19834abd945515a13986f8dd