Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Antonio Garcia Guerra"'
Autor:
Anna J Kordala, Jessica Stoodley, Nina Ahlskog, Muhammad Hanifi, Antonio Garcia Guerra, Amarjit Bhomra, Wooi Fang Lim, Lyndsay M Murray, Kevin Talbot, Suzan M Hammond, Matthew JA Wood, Carlo Rinaldi
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 11, Pp 1-16 (2023)
Abstract Spinal muscular atrophy (SMA) is a leading genetic cause of infant mortality. The advent of approved treatments for this devastating condition has significantly changed SMA patients' life expectancy and quality of life. Nevertheless, these a
Externí odkaz:
https://doaj.org/article/0a6be327d14849d1ae2a1fc49bf73886
Autor:
Olivier G. de Jong, Daniel E. Murphy, Imre Mäger, Eduard Willms, Antonio Garcia-Guerra, Jerney J. Gitz-Francois, Juliet Lefferts, Dhanu Gupta, Sander C. Steenbeek, Jacco van Rheenen, Samir El Andaloussi, Raymond M. Schiffelers, Matthew J. A. Wood, Pieter Vader
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Extracellular vesicles (EV) facilitate intercellular transfer of biological material including RNA, but the regulatory mechanisms for their formation and transfer are incompletely known. Here the authors develop a CRISPR-based reporting system to det
Externí odkaz:
https://doaj.org/article/1db2023ed1d94f558ace5b4d70bad252
Autor:
Olivier G. de Jong, Daniel E. Murphy, Imre Mäger, Eduard Willms, Antonio Garcia-Guerra, Jerney J. Gitz-Francois, Juliet Lefferts, Dhanu Gupta, Sander C. Steenbeek, Jacco van Rheenen, Samir El Andaloussi, Raymond M. Schiffelers, Matthew J. A. Wood, Pieter Vader
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/c79299af34a74ba6b50b6a6e5e719242
Autor:
Matthew J.A. Wood, Raymond M. Schiffelers, Dhanu Gupta, Samir El Andaloussi, Olivier G. de Jong, Antonio Garcia-Guerra, Jerney J. Gitz-Francois, Juliet Lefferts, Sander C. Steenbeek, Jacco van Rheenen, Imre Mäger, Pieter Vader, Daniel E. Murphy, Eduard Willms
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Autor:
John F. Morris, Samir El-Andaloussi, Mark A. Behlke, Aurélie Goyenvalle, Matthew J.A. Wood, Graham McClorey, Yoshitsugu Aoki, Amer F. Saleh, Leif Benner, Joel Z. Nordin, Anna M.L. Coenen-Stass, Liz O'Donovan, Christian J. Leumann, Taavi Lehto, Antonio Garcia-Guerra, Siamon Gordon, Michael J. Gait, Kariem Ezzat, Taeyoung Koo, Branislav Dugovic
Publikováno v:
Ahmed, Kariem; Aoki, Yoshitsugu; Koo, Taeyoung; McClorey, Graham; Benner, Leif; Coenen-Stass, Anna; O'Donovan, Liz; Lehto, Taavi; Garciaguerra, Antonio; Nordin, Joel Zacharias; Saleh, Amer F.; Behlke, Mark A.; Morris, John; Goyenvalle, Aurelie; Dugovic, Branislav; Leumann, Christian Joerg; Gordon, Siamon; Gait, Michael J.; El-Andaloussi, Samir and Wood, Matthew J. A. (2015). Self-assembly into nanoparticles is essential for receptor mediated uptake of therapeutic antisense oligonucleotides. Nano letters, 15(7), pp. 4364-4374. American Chemical Society 10.1021/acs.nanolett.5b00490
Antisense oligonucleotides (ASOs) have the potential to revolutionize medicine due to their ability to manipulate gene function for therapeutic purposes. ASOs are chemically modified and/or incorporated within nanoparticles to enhance their stability