Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Antonio G. Castro"'
Autor:
Fernanda Zamboni, Ibrahim F. Cengiz, Ana M. Barbosa, Antonio G. Castro, Rui L. Reis, Joaquim M. Oliveira, Maurice N. Collins
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1925 (2021)
Female mice (Black 6 strain) (C57BL/6) aged 6 weeks were subject to low dose streptozotocin (STZ) treatment for five consecutive days to mimic type 1 diabetes mellitus (T1DM) with insulitis. At two weeks after STZ injections, evaluation of the elevat
Externí odkaz:
https://doaj.org/article/551a2836e0d044ceacd103da40c17c9f
Autor:
Daniel B. Rodrigues, Helena R. Moreira, Mariana T. Cerqueira, Alexandra P. Marques, António G. Castro, Rui L. Reis, Rogério P. Pirraco
Publikováno v:
Biomaterials Research, Vol 26, Iss 1, Pp 1-19 (2022)
Abstract Background T cell priming has been shown to be a powerful immunotherapeutic approach for cancer treatment in terms of efficacy and relatively weak side effects. Systems that optimize the stimulation of T cells to improve therapeutic efficacy
Externí odkaz:
https://doaj.org/article/9e240c53884d402faeacec8e70cfcb61
Autor:
Catarina M. Ferreira, Ana Margarida Barbosa, Palmira Barreira-Silva, Ricardo Silvestre, Cristina Cunha, Agostinho Carvalho, Fernando Rodrigues, Margarida Correia-Neves, António G. Castro, Egídio Torrado
Publikováno v:
JCI Insight, Vol 6, Iss 21 (2021)
Cytokine-producing CD4+ T cells play a crucial role in the control of Mycobacterium tuberculosis infection; however, there is a delayed appearance of effector T cells in the lungs following aerosol infection. The immunomodulatory cytokine IL-10 antag
Externí odkaz:
https://doaj.org/article/35c15db18b774497a118c4122f4e11f5
Autor:
Ana Margarida Barbosa, Olga Martinho, Rosete Nogueira, Juliana Campos, Liliana Lobo, Henrique Pinto, Adhemar Longatto-Filho, António G. Castro, Sandra F. Martins, Egídio Torrado
Publikováno v:
Biology, Vol 10, Iss 8, p 808 (2021)
Tumor-infiltrating lymphocytes include heterogeneous populations of T lymphocytes that play crucial roles in the tumor immune response; importantly, their presence in the tumor tissue may predict clinical outcomes. Therefore, we herein studied the pr
Externí odkaz:
https://doaj.org/article/50e3c04807374406a7264ca48bb9d662
Autor:
Kiranmai Bhatt, Henrique Machado, Nuno S. Osório, Jeremy Sousa, Filipa Cardoso, Carlos Magalhães, Bing Chen, Mei Chen, John Kim, Albel Singh, Catarina M. Ferreira, António G. Castro, Egidio Torrado, William R. Jacobs, Apoorva Bhatt, Margarida Saraiva
Publikováno v:
mSphere, Vol 3, Iss 5 (2018)
ABSTRACT Nonribosomal peptide synthases produce short peptides in a manner that is distinct from classical mRNA-dependent ribosome-mediated translation. The Mycobacterium tuberculosis genome harbors a nonribosomal peptide synthase gene, nrp, which is
Externí odkaz:
https://doaj.org/article/1ca69f777d56487ab7f418ab4f795bf6
Autor:
Joana Gaifem, Luís G. Gonçalves, Ricardo J. Dinis-Oliveira, Cristina Cunha, Agostinho Carvalho, Egídio Torrado, Fernando Rodrigues, Margarida Saraiva, António G. Castro, Ricardo Silvestre
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Dietary nutrients have emerged as potential therapeutic adjuncts for inflammatory bowel disease (IBD) given their impact on intestinal homeostasis through the modulation of immune response, gut microbiota composition and epithelial barrier stability.
Externí odkaz:
https://doaj.org/article/24c3a209f76b403c96121bbcb81cc4e6
Autor:
Jenny Carmona, Andrea Cruz, Lucia Moreira-Teixeira, Carole Sousa, Jeremy Sousa, Nuno S Osorio, Ana L Saraiva, Stefan Svenson, Gunilla Kallenius, Jorge Pedrosa, Fernando Rodrigues, Antonio G Castro, Margarida Saraiva
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67277 (2013)
Tuberculosis associates with a wide spectrum of disease outcomes. The Beijing (Bj) lineage of Mycobacterium tuberculosis (Mtb) is suggested to be more virulent than other Mtb lineages and prone to elicit non-protective immune responses. However, high
Externí odkaz:
https://doaj.org/article/2e41877c6a4d481eb79def6f04b12ce5