Výsledky vyhledávání - "Antonio Felici"

Akademický článek

Targeting virulence regulation to disarm Acinetobacter baumannii pathogenesis

Autor: Vincent Trebosc, Valentina Lucchini, Mohit Narwal, Basil Wicki, Sarah Gartenmann, Birgit Schellhorn, Julian Schill, Marilyne Bourotte, Daniel Frey, Jürgen Grünberg, Andrej Trauner, Livia Ferrari, Antonio Felici, Olivia L. Champion, Marc Gitzinger, Sergio Lociuro, Richard A. Kammerer, Christian Kemmer, Michel Pieren

Publikováno v: Virulence, Vol 13, Iss 1, Pp 1868-1883 (2022)

The development of anti-virulence drug therapy against Acinetobacter baumannii infections would provide an alternative to traditional antibacterial therapy that are increasingly failing. Here, we demonstrate that the OmpR transcriptional regulator pl

Externí odkaz: https://doaj.org/article/15918578828b477baf8ad5a55dd06209

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Akademický článek

Tackling recalcitrant Pseudomonas aeruginosa infections in critical illness via anti-virulence monotherapy

Autor: Vijay K. Singh, Marianna Almpani, Damien Maura, Tomoe Kitao, Livia Ferrari, Stefano Fontana, Gabriella Bergamini, Elisa Calcaterra, Chiara Pignaffo, Michele Negri, Thays de Oliveira Pereira, Frances Skinner, Manos Gkikas, Danielle Andreotti, Antonio Felici, Eric Déziel, Francois Lépine, Laurence G. Rahme

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)

Pseudomonas aeruginosa infections are increasingly difficult to treat due to the development of antimicrobial resistance. Here, the authors describe the synthesis, characterisation and efficacy of a quorum sensing inhibitor.

Externí odkaz: https://doaj.org/article/48ce72987f594e88a8d110a27c21b96f

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Akademický článek

A Niclosamide-releasing hot-melt extruded catheter prevents Staphylococcus aureus experimental biomaterial-associated infection

Autor: Jesus Augusto Vazquez-Rodriguez, Bahaa Shaqour, Clara Guarch-Pérez, Emilia Choińska, Martijn Riool, Bart Verleije, Koen Beyers, Vivian J. A. Costantini, Wojciech Święszkowski, Sebastian A. J. Zaat, Paul Cos, Antonio Felici, Livia Ferrari

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)

Abstract Biomaterial-associated infections are a major healthcare challenge as they are responsible for high disease burden in critically ill patients. In this study, we have developed drug-eluting antibacterial catheters to prevent catheter-related

Externí odkaz: https://doaj.org/article/063a964a93684d7aa1e518dfdf52a798

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Akademický článek

Interlaboratory study for the evaluation of three microtiter plate-based biofilm quantification methods

Autor: Jontana Allkja, Frits van Charante, Juliana Aizawa, Inés Reigada, Clara Guarch-Pérez, Jesus Augusto Vazquez-Rodriguez, Paul Cos, Tom Coenye, Adyary Fallarero, Sebastian A. J. Zaat, Antonio Felici, Livia Ferrari, Nuno F. Azevedo, Albert E. Parker, Darla M. Goeres

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)

Abstract Microtiter plate methods are commonly used for biofilm assessment. However, results obtained with these methods have often been difficult to reproduce. Hence, it is important to obtain a better understanding of the repeatability and reproduc

Externí odkaz: https://doaj.org/article/e846ad0bf22d451e93a5a430e7a0ebe2

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Akademický článek

OMN6 a novel bioengineered peptide for the treatment of multidrug resistant Gram negative bacteria

Autor: Shira Mandel, Janna Michaeli, Noa Nur, Isabelle Erbetti, Jonathan Zazoun, Livia Ferrari, Antonio Felici, Moshe Cohen-Kutner, Niv Bachnoff

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)

Abstract New antimicrobial agents are urgently needed, especially to eliminate multidrug resistant Gram-negative bacteria that stand for most antibiotic-resistant threats. In the following study, we present superior properties of an engineered antimi

Externí odkaz: https://doaj.org/article/83a72ed367e14c80809b6afdced28df3

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Akademický článek

Mouse pneumonia model by Acinetobacter baumannii multidrug resistant strains: Comparison between intranasal inoculation, intratracheal instillation and oropharyngeal aspiration techniques.

Autor: Gabriella Bergamini, Maria Elisa Perico, Stefano Di Palma, Daniela Sabatini, Filippo Andreetta, Rossella Defazio, Antonio Felici, Livia Ferrari

Publikováno v: PLoS ONE, Vol 16, Iss 12, p e0260627 (2021)

Infectious pneumonia induced by multidrug resistant (MDR) Acinetobacter baumannii strains is among the most common and deadly forms of healthcare acquired infections. Over the years, different strategies have been put in place to increase host suscep

Externí odkaz: https://doaj.org/article/1c83d24284dd4e21a3546837535c1741

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Akademický článek

Molecular Insights into Function and Competitive Inhibition of Pseudomonas aeruginosa Multiple Virulence Factor Regulator

Autor: Tomoe Kitao, Francois Lepine, Seda Babloudi, Frederick Walte, Stefan Steinbacher, Klaus Maskos, Michael Blaesse, Michele Negri, Michael Pucci, Bob Zahler, Antonio Felici, Laurence G. Rahme

Publikováno v: mBio, Vol 9, Iss 1 (2018)

ABSTRACT New approaches to antimicrobial drug discovery are urgently needed to combat intractable infections caused by multidrug-resistant (MDR) bacteria. Multiple virulence factor regulator (MvfR or PqsR), a Pseudomonas aeruginosa quorum sensing tra

Externí odkaz: https://doaj.org/article/3a5377cb41f442beb617a5562a681113

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Interlaboratory study for the evaluation of three microtiter plate-based biofilm quantification methods

Autor: Antonio Felici, Frits van Charante, Darla M. Goeres, Paul Cos, Inés Reigada, Sebastian A. J. Zaat, Livia Ferrari, Jesus Augusto Vazquez-Rodriguez, Albert E. Parker, Tom Coenye, Adyary Fallarero, Clara Guarch-Pérez, Jontana Allkja, Nuno F. Azevedo, Juliana Aizawa

Publikováno v: Scientific reports, 11(1):13779. Nature Publishing Group
Scientific Reports
Scientific reports
SCIENTIFIC REPORTS
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)

Microtiter plate methods are commonly used for biofilm assessment. However, results obtained with these methods have often been difficult to reproduce. Hence, it is important to obtain a better understanding of the repeatability and reproducibility o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bc52ce9b27e92567cdd7af12e9064f6
https://pure.amc.nl/en/publications/interlaboratory-study-for-the-evaluation-of-three-microtiter-platebased-biofilm-quantification-methods(255f5819-f41b-4aee-bd4c-6a698493d7f4).html

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Mouse pneumonia model by Acinetobacter baumannii multidrug resistant strains: Comparison between intranasal inoculation, intratracheal instillation and oropharyngeal aspiration techniques

Autor: Filippo Andreetta, Livia Ferrari, Maria Elisa Perico, Rossella Defazio, Daniela Sabatini, Gabriella Bergamini, Stefano Di Palma, Antonio Felici

Publikováno v: PLoS ONE, Vol 16, Iss 12, p e0260627 (2021)
PLoS ONE

Infectious pneumonia induced by multidrug resistant (MDR)Acinetobacter baumanniistrains is among the most common and deadly forms of healthcare acquired infections. Over the years, different strategies have been put in place to increase host suscepti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55788804a87c4728804dcad3f71d2535
https://doaj.org/article/1c83d24284dd4e21a3546837535c1741

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