Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Antonio E. Rusiñol"'
Publikováno v:
Mediators of Inflammation, Vol 2014 (2014)
Externí odkaz:
https://doaj.org/article/54afaffd29e3465c838c135d3ecada4d
Autor:
Antonio E. Rusiñol, Ramanujan S. Hegde, Steven L. Chuck, Vishwanath R. Lingappa, Jean E. Vance
Publikováno v:
Journal of Lipid Research, Vol 39, Iss 6, Pp 1287-1294 (1998)
One potential mechanism by which apolipoprotein (apo) B secretion is regulated is via transient pausing during translocation across the endoplasmic reticulum membrane. We have previously shown that translocation and secretion of full-length and trunc
Externí odkaz:
https://doaj.org/article/79aea77fb2e344e592506dc6eb9e3d39
Autor:
Brian M. Cartwright, Hui Tang, Ji Liu, Antonio E. Rusiñol, Benjamin Hilton, Phillip R. Musich, Youjie Wang, Rowdy Jones, Yiyong Liu, Yue Zou, Maya Breitman
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 31(9)
Hutchinson-Gilford progeria syndrome (HGPS) is a rare genetic disorder that is caused by a point mutation in the LMNA gene, resulting in production of a truncated farnesylated-prelamin A protein (progerin). We previously reported that XPA mislocalize
Autor:
Vinod K. Mishra, Alok Agrawal, Sanjay K. Singh, Antonio E. Rusiñol, Avinash Thirumalai, David J. Hammond, David A. Johnson, Michael K. Pangburn
Publikováno v:
Journal of Biological Chemistry. 287:3550-3558
C-reactive protein (CRP) is a cyclic pentameric protein whose major binding specificity, at physiological pH, is for substances bearing exposed phosphocholine moieties. Another pentameric form of CRP, which exists at acidic pH, displays binding activ
Autor:
Sanjay K. Singh, David J. Hammond, Antonio E. Rusiñol, James A. Thompson, Bradley W. Beeler, Alok Agrawal, Michael K. Pangburn, Lawrence A. Potempa
Publikováno v:
Journal of Biological Chemistry. 285:36235-36244
C-reactive protein (CRP) is a phylogenetically conserved protein; in humans, it is present in the plasma and at sites of inflammation. At physiological pH, native pentameric CRP exhibits calcium-dependent binding specificity for phosphocholine. In th
Autor:
Alok Agrawal, Sanjay Singh, Lawrence A. Potempa, David J. Hammond, Antonio E. Rusiñol, Madathilparambil V. Suresh
Publikováno v:
Clinica Chimica Acta. 406:151-155
Background The 5 subunits of native pentameric C-reactive protein (CRP) are dissociated to generate the monomeric form of CRP (mCRP) in some in vitro conditions, both physiological and non-physiological, and also in vivo . Many bioactivities of mCRP
Autor:
Jonathan P. Moorman, Deborah Prayther, Sanjay Singh, Alok Agrawal, Antonio E. Rusiñol, Madathilparambil V. Suresh
Publikováno v:
The Journal of Immunology. 180:4316-4322
The formation of low-density lipoprotein (LDL) cholesterol-loaded macrophage foam cells contributes to the development of atherosclerosis. C-reactive protein (CRP) binds to atherogenic forms of LDL, but the role of CRP in foam cell formation is uncle
Autor:
Michael S. Sinensky, Antonio E. Rusiñol, Thomas Dechat, Robert D. Goldman, Takeshi Shimi, H. Peter Spielmann, Stephen A. Adam, Douglas A. Andres
Publikováno v:
Proceedings of the National Academy of Sciences. 104:4955-4960
Mutations in the gene encoding nuclear lamin A (LA) cause the premature aging disease Hutchinson–Gilford Progeria Syndrome. The most common of these mutations results in the expression of a mutant LA, with a 50-aa deletion within its C terminus. In
Publikováno v:
Journal of Cell Science. 119:4644-4649
The genetic diseases Hutchinson-Gilford progeria syndrome (HGPS) and restrictive dermopathy (RD) arise from accumulation of farnesylated prelamin A because of defects in the lamin A maturation pathway. Both of these diseases exhibit symptoms that can
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 26:2012-2018
Objective— HSPA12B is the newest member of HSP70 family of proteins and is enriched in atherosclerotic lesions. This study focused on HSPA12B expression in mice and its involvement in angiogenesis. Methods and Results— The expression of HSPA12B i