Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Antonio E. Chambers"'
Autor:
Joseph M. Gumina, Adam E. Richardson, Mahmudul Hasan Shojiv, Antonio E. Chambers, Siara N. Sandwith, Michael A. Reisinger, Taylor J. Karns, Tyler L. Osborne, Hasna N. Alashi, Quinn T. Anderson, Meredith E. Sharlow, Dylan C. Seiler, Evan M. Rogers, Anna R. Bartosik, Melissa A. Smaldino, James P. Vaughn, Yuh-Hwa Wang, Philip J. Smaldino, Robert A. Haney
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1753 (2024)
G-quadruplexes (G4s) are secondary DNA and RNA structures stabilized by positive cations in a central channel formed by stacked tetrads of Hoogsteen base-paired guanines. G4s form from G-rich sequences across the genome, whose biased distribution in
Externí odkaz:
https://doaj.org/article/5ce20ac284214326b4661fa852e80435
Autor:
Adam. E. Richardson, Zachary. A. Zentz, Antonio E. Chambers, Siara N. Sandwith, Michael A. Reisinger, Destinee W. Saunders, Joshua D. Tompkins, Arthur D. Riggs, Eric D. Routh, Eric M. Rubenstein, Melissa A. Smaldino, James P. Vaughn, Robert A. Haney, Philip J. Smaldino
Publikováno v:
ACS Omega, Vol 5, Iss 38, Pp 24916-24926 (2020)
Externí odkaz:
https://doaj.org/article/3e864a15bddf436ab2a010b8f3d9be8d
Autor:
Ben A. Evans, Olivia L. Smith, Ethan S. Pickerill, Mary K. York, Kristen J.P. Buenconsejo, Antonio E. Chambers, Douglas A. Bernstein
Publikováno v:
PeerJ, Vol 6, p e4920 (2018)
Introduction of point mutations to a gene of interest is a powerful tool when determining protein function. CRISPR-mediated genome editing allows for more efficient transfer of a desired mutation into a wide range of model organisms. Traditionally, P
Externí odkaz:
https://doaj.org/article/569f4fcf842845ffb6274f2722cf3206
Autor:
Melissa A. Smaldino, Adam E. Richardson, Siara N. Sandwith, Emily S. Schmidt, Philip J. Smaldino, Antonio E. Chambers, Destinee W. Saunders, Michael A. Reisinger
Publikováno v:
The American Biology Teacher. 82:624-627
We present a novel adaptation of a typical science laboratory protocol, which we have termed multi-view protocols (MVPs). The purpose of MVPs is to answer and link three common questions asked by students when first learning a laboratory technique: (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c373873157c9478798fa7bf71a5dfeb5
https://doi.org/10.1525/abt.2020.82.9.624
https://doi.org/10.1525/abt.2020.82.9.624
Autor:
Philip J. Smaldino, Amy Krans, Yi-Ju Tseng, Yuh-Hwa Wang, Adam E. Richardson, Katelyn M. Green, James P. Vaughn, Meredith E. Sharlow, Eric D. Routh, Peter K. Todd, Melissa A. Smaldino, Siara N. Sandwith, Antonio E. Chambers, Michael A. Reisinger, Heather M Raimer
Publikováno v:
The Journal of Biological Chemistry
GGGGCC (G4C2) hexanucleotide repeat expansions in the endosomal trafficking gene C9orf72 are the most common genetic cause of ALS and frontotemporal dementia. Repeat-associated non-AUG (RAN) translation of this expansion through near-cognate initiati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c3ff8599557e7269f89d5bb5b0f3c3c
http://europepmc.org/articles/PMC8326427
http://europepmc.org/articles/PMC8326427
Autor:
Katelyn M. Green, Melissa A. Smaldino, Peter K. Todd, Amy Krans, Meredith E. Sharlow, Michael A. Reisinger, Antonio E. Chambers, Yi-Ju Tseng, Yuh-Hwa Wang, Heather M Raimer, Siara N. Sandwith, Eric D. Routh, Philip J. Smaldino, James P. Vaughn, Adam E. Richardson
GGGGCC (G4C2) hexanucleotide repeat expansions (HRE) in C9orf72 are the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Repeat-associated non-AUG (RAN) translation of this expansion generates toxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1356fcf6b9169f89aae2d66393fd98f
https://doi.org/10.1101/2021.04.25.441260
https://doi.org/10.1101/2021.04.25.441260
Autor:
Siara N. Sandwith, Antonio E. Chambers, Destinee W. Saunders, Joshua D. Tompkins, Zachary A Zentz, Eric D. Routh, Michael A. Reisinger, Philip J. Smaldino, Adam E. Richardson, Eric M. Rubenstein, Arthur D. Riggs, Robert A. Haney, Melissa A. Smaldino, James P. Vaughn
Publikováno v:
ACS Omega, Vol 5, Iss 38, Pp 24916-24926 (2020)
G-quadruplexes (G4s) are nucleic acid structures found enriched within gene regulatory sequences. G4s control fundamental cellular processes, including replication, transcription, and translation. Proto-oncogenes are enriched with G4 sequences, while
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad3d002f71b5cc6cd7707bcad911833a
https://pubmed.ncbi.nlm.nih.gov/33015511
https://pubmed.ncbi.nlm.nih.gov/33015511
Autor:
Antonio E, Chambers, Adam E, Richardson, David F, Read, Thomas J, Waller, Douglas A, Bernstein, Philip J, Smaldino
Publikováno v:
J Vis Exp
N(6)-isopentenyladenosine RNA modifications are functionally diverse and highly conserved among prokaryotes and eukaryotes. One of the most highly conserved N(6)-isopentenyladenosine modifications occurs at the A37 position in a subset of tRNAs. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4c1c1a17284fc6b923bf957fdcc93c79
https://pubmed.ncbi.nlm.nih.gov/30346392
https://pubmed.ncbi.nlm.nih.gov/30346392
Autor:
Adam E. Richardson, Philip J. Smaldino, Antonio E. Chambers, Thomas J. Waller, Douglas A. Bernstein, David F. Read
Publikováno v:
Journal of Visualized Experiments.
N6-isopentenyladenosine RNA modifications are functionally diverse and highly conserved among prokaryotes and eukaryotes. One of the most highly conserved N6-isopentenyladenosine modifications occurs at the A37 position in a subset of tRNAs. This mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::955667fc69c632de3a8f4cd99bdd73c0
https://doi.org/10.3791/58100
https://doi.org/10.3791/58100
Autor:
Mary K. York, Ethan S. Pickerill, Antonio E. Chambers, Ben A. Evans, Kristen J.P. Buenconsejo, Douglas A. Bernstein, Olivia L. Smith
Publikováno v:
PeerJ
PeerJ, Vol 6, p e4920 (2018)
PeerJ, Vol 6, p e4920 (2018)
Introduction of point mutations to a gene of interest is a powerful tool when determining protein function. CRISPR-mediated genome editing allows for more efficient transfer of a desired mutation into a wide range of model organisms. Traditionally, P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5288fabaf42978ae92035e3bd15a06b7
http://europepmc.org/articles/PMC5994162
http://europepmc.org/articles/PMC5994162