Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Antonio Contestabile"'
Publikováno v:
Cerebral Cortex. 30:1393-1406
Neurotransmitters can be released either synchronously or asynchronously with respect to action potential timing. Synapsins (Syns) are a family of synaptic vesicle (SV) phosphoproteins that assist gamma-aminobutyric acid (GABA) release and allow a ph
Autor:
Marco Virgili, Barbara Monti, Emiliano Peña-Altamira, Federica Prati, Maria Laura Bolognesi, Antonio Contestabile, Francesca Massenzio
Publikováno v:
Expert Opinion on Therapeutic Targets. 20:627-640
INTRODUCTION: The importance of microglia in most neurodegenerative pathologies, from Parkinson's disease to amyotrophic lateral sclerosis and Alzheimer's disease, is increasingly recognized. Until few years ago, microglial activation in pathological
Autor:
Davide Pozzi, Gabriele Lignani, Pierluigi Valente, Antonio Contestabile, Enrico Castroflorio, Fabio Benfenati, F Pecoraro-Bisogni, Anna Rocchi, Marta Orlando, Manuela Massacesi, Pietro Baldelli, Cosimo Prestigio
Publikováno v:
Molecular neurobiology. 55(6)
Homeostatic plasticity is a regulatory feedback response in which either synaptic strength or intrinsic excitability can be adjusted up or down to offset sustained changes in neuronal activity. Although a growing number of evidences constantly provid
Autor:
Silvia Sintoni, Antonio Contestabile
Publikováno v:
Current Pharmaceutical Design. 19:5043-5050
Post-translational modification of histones is a primary mechanism through which epigenetic regulation of DNA transcription does occur. Among these modifications, regulation of histone acetylation state is an important tool to influence gene expressi
Zinc is a trace element important for synaptic plasticity, learning and memory. Zinc deficiency, both during pregnancy and after birth, impairs cognitive performance and, in addition to memory deficits, also results in alterations of attention, activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dca1eefe937553ba30d9eabea2760003
http://hdl.handle.net/11585/543213
http://hdl.handle.net/11585/543213
Autor:
Antonio Contestabile
Publikováno v:
The Cerebellum. 11:50-61
More than 20 years of research have firmly established important roles of the diffusible messenger molecule, nitric oxide (NO), in cerebellar development and function. Granule neurons are main players in every NO-related mechanism involving cerebella
Publikováno v:
Neuroscience Letters. 448:74-78
Microglia, the immune cells of the mammalian CNS, have often been indicated as dangerous effector cells for their activation in response to traumatic CNS injuries or immunological stimuli and for their involvement in many chronic neurodegenerative di
Autor:
Antonio Contestabile
Publikováno v:
Progress in Neurobiology. 84:317-328
Nitric oxide (NO), a diffusible molecule acting as an intercellular and intracellular messenger in many tissues, plays multiple roles in the nervous system. In addition to regulating proliferation, survival and differentiation of neurons, NO is also
Publikováno v:
Neurochemical Research. 33:318-327
The so-called "cholinergic hypothesis" assumes that degenerative dysfunction of the cholinergic system originating in the basal forebrain and innervating several cortical regions and the hippocampus, is related to memory impairment and neurodegenerat
Autor:
Elisabetta Polazzi, Barbara Monti, Antonio Contestabile, Christophe Crochemore, Marco Virgili, Laura Batti
Publikováno v:
Journal of Neurochemistry. 103:518-530
The physiological role of alpha-synuclein, a protein found enriched in intraneuronal deposits characterizing Parkinson's disease, is debated. While its aggregation is usually considered linked to neuropathology, its normal function may be related to