Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Antonio Colaprico"'
Autor:
Brian D. Lehmann, Antonio Colaprico, Tiago C. Silva, Jianjiao Chen, Hanbing An, Yuguang Ban, Hanchen Huang, Lily Wang, Jamaal L. James, Justin M. Balko, Paula I. Gonzalez-Ericsson, Melinda E. Sanders, Bing Zhang, Jennifer A. Pietenpol, X. Steven Chen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Triple negative breast cancer can be divided into additional subtypes. Here, using omics analyses, the authors show that in the mesenchymal subtype expression of MHC-1 is repressed and that this can be restored by using drugs that target subunits of
Externí odkaz:
https://doaj.org/article/0cee2f33898a4f86bcaa6cb1a2d39df1
Autor:
Antonio Colaprico, Catharina Olsen, Matthew H. Bailey, Gabriel J. Odom, Thilde Terkelsen, Tiago C. Silva, André V. Olsen, Laura Cantini, Andrei Zinovyev, Emmanuel Barillot, Houtan Noushmehr, Gloria Bertoli, Isabella Castiglioni, Claudia Cava, Gianluca Bontempi, Xi Steven Chen, Elena Papaleo
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Identification of cancer driver genes, especially those that can act as tumour suppressors or oncogenes depending on context, remains a challenge. Here, the authors introduce Moonlight, a tool that integrates multi-omic data to address this challenge
Externí odkaz:
https://doaj.org/article/17a5443f838e4ce7b405503b7875ae15
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Recent advances in technology have made multi-omics datasets increasingly available to researchers. To leverage the wealth of information in multi-omics data, a number of integrative analysis strategies have been proposed recently. However, effective
Externí odkaz:
https://doaj.org/article/d9cdc443123445ad9ab39477b44179b2
Autor:
Min Lu, Yifan Sha, Tiago C. Silva, Antonio Colaprico, Xiaodian Sun, Yuguang Ban, Lily Wang, Brian D. Lehmann, X. Steven Chen
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Cell–cell interactions (CCIs) and cell–cell communication (CCC) are critical for maintaining complex biological systems. The availability of single-cell RNA sequencing (scRNA-seq) data opens new avenues for deciphering CCIs and CCCs through ident
Externí odkaz:
https://doaj.org/article/c03b4ebffd10498d9be64115fadf21eb
Autor:
Ho Lam Chan, Felipe Beckedorff, Yusheng Zhang, Jenaro Garcia-Huidobro, Hua Jiang, Antonio Colaprico, Daniel Bilbao, Maria E. Figueroa, John LaCava, Ramin Shiekhattar, Lluis Morey
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
The role of Polycomb Repressive Complex 1 (PRC1) is well described in development. Here, the authors investigate canonical PRC1’s regulation of transcriptional programs in breast cancer where, in addition to its repressive function, it is also recr
Externí odkaz:
https://doaj.org/article/cc957fd0d811463b9e87699141c6c633
Autor:
Claudia Cava, Gloria Bertoli, Antonio Colaprico, Catharina Olsen, Gianluca Bontempi, Isabella Castiglioni
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-16 (2018)
Abstract Background Modern high-throughput genomic technologies represent a comprehensive hallmark of molecular changes in pan-cancer studies. Although different cancer gene signatures have been revealed, the mechanism of tumourigenesis has yet to be
Externí odkaz:
https://doaj.org/article/5b6c72cc98ca425a8180f8c1d2c8475b
Autor:
Mohamed Mounir, Marta Lucchetta, Tiago C Silva, Catharina Olsen, Gianluca Bontempi, Xi Chen, Houtan Noushmehr, Antonio Colaprico, Elena Papaleo
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 3, p e1006701 (2019)
The advent of Next-Generation Sequencing (NGS) technologies has opened new perspectives in deciphering the genetic mechanisms underlying complex diseases. Nowadays, the amount of genomic data is massive and substantial efforts and new tools are requi
Externí odkaz:
https://doaj.org/article/a0b973f08464438d9caf37aa16e15f17
Autor:
Tiago C. Silva, Antonio Colaprico, Catharina Olsen, Fulvio D'Angelo, Gianluca Bontempi, Michele Ceccarelli, Houtan Noushmehr
Publikováno v:
F1000Research, Vol 5 (2016)
Biotechnological advances in sequencing have led to an explosion of publicly available data via large international consortia such as The Cancer Genome Atlas (TCGA), The Encyclopedia of DNA Elements (ENCODE), and The NIH Roadmap Epigenomics Mapping C
Externí odkaz:
https://doaj.org/article/27cbb5bda8c7475cb286a5b19d19463f
Autor:
Maria E. Figueroa, H. Leighton Grimes, Nathan Salomonis, Rafael Bejar, R. Coleman Lindsley, Tingting Qin, Antonio Colaprico, André Olsson, Alejandro Roisman, Hsuan-Ting Huang, Emmalee R. Adelman
Overlap with aging signatures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::922f014bbd864c7286846a09f4be6114
https://doi.org/10.1158/2159-8290.22536808.v1
https://doi.org/10.1158/2159-8290.22536808.v1
Autor:
Maria E. Figueroa, H. Leighton Grimes, Nathan Salomonis, Rafael Bejar, R. Coleman Lindsley, Tingting Qin, Antonio Colaprico, André Olsson, Alejandro Roisman, Hsuan-Ting Huang, Emmalee R. Adelman
Aging is associated with functional decline of hematopoietic stem cells (HSC) as well as an increased risk of myeloid malignancies. We performed an integrative characterization of epigenomic and transcriptomic changes, including single-cell RNA seque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3702b1843fbd134c8dd12ffd638bbbe
https://doi.org/10.1158/2159-8290.c.6548245.v1
https://doi.org/10.1158/2159-8290.c.6548245.v1