Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Antonio Carlos Manucci"'
Autor:
Cecilia Benazzato, Fernando Lojudice, Felizia Pöehlchen, Paulo Emílio Corrêa Leite, Antonio Carlos Manucci, Vanessa Van der Linden, Patricia Jungmann, Mari C. Sogayar, Alexandre Bruni-Cardoso, Fabiele B. Russo, Patricia Beltrão-Braga
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Zika virus (ZIKV) infection was first reported in 2015 in Brazil as causing microcephaly and other developmental abnormalities in newborns, leading to the identification of Congenital Zika Syndrome (CZS). Viral infections have been considere
Externí odkaz:
https://doaj.org/article/004a408e636a4095953d4315fb6434fa
Cell context is key for cell phenotype. Using physiologically relevant models of laminin-rich ECM (lrECM) induction of mammary epithelial cell quiescence and differentiation, we have provided a landscape of the status of key molecular players involve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d331702fdbd85b6f3fb07d4ab2c2834
https://doi.org/10.1101/2023.03.13.532403
https://doi.org/10.1101/2023.03.13.532403
Autor:
Ana Paula Zen Petisco Fiore, Ana Maria Rodrigues, Helder Veras Ribeiro-Filho, Antonio Carlos Manucci, Pedro de Freitas Ribeiro, Mayara Carolinne Silva Botelho, Christine Vogel, Paulo Sergio Lopes-de-Oliveira, Michele Pagano, Alexandre Bruni-Cardoso
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
The Hippo pathway plays central roles in relaying mechanical signals during development and tumorigenesis, but how the proteostasis of the Hippo kinase MST2 is regulated remains unknown. Here, we found that chemical inhibition of proteasomal proteoly
Autor:
Flavia Carla Meotti, Isaac Araújo Matos, Alexandre Bruni-Cardoso, Sven T. Sowa, Nicolas C. Hoch, Lillian Cristina Russo, Keith W. Caldecott, Deborah Schechtman, Katie L. Dale, Antonio Carlos Manucci, Lari Lehtiö, Rebeka Tomasin
SARS-CoV-2 non-structural protein 3 (Nsp3) contains a macrodomain that is essential for virus replication and is thus an attractive target for drug development. This macrodomain is thought to counteract the host interferon (IFN) response, an importan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca012b6b7170ce0cd5c7e3e76cfd2859
https://doi.org/10.1101/2021.04.06.438552
https://doi.org/10.1101/2021.04.06.438552
Autor:
Michele Pagano, Silva Botelho Mc, da Silva Amr, Ribeiro Hv, Fiore Apzp, Alexandre Bruni-Cardoso, Antonio Carlos Manucci, Oliveira Psl, Ribeiro PdF
Tumor microenvironments display disrupted mechanical properties, including altered extracellular matrix (ECM) rigidity. ECM stiffening perturbs cell tensional homeostasis resulting in activation of mechanosensing transcriptional co-activators, such a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c233bd8143026410e3e3975978ea39d
https://doi.org/10.1101/2021.01.31.429078
https://doi.org/10.1101/2021.01.31.429078
Autor:
Lari Lehtiö, Deborah Schechtman, Lilian C. Russo, Flavia Carla Meotti, Alexandre Bruni-Cardoso, Sven T. Sowa, Katie Dale, Nicolas C. Hoch, Rebeka Tomasin, Isaac Araújo Matos, Antonio Carlos Manucci, Keith W. Caldecott
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
The Journal of Biological Chemistry
Universidade de São Paulo (USP)
instacron:USP
The Journal of Biological Chemistry
SARS-CoV-2 non-structural protein 3 (Nsp3) contains a macrodomain that is essential for coronavirus pathogenesis and is thus an attractive target for drug development. This macrodomain is thought to counteract the host interferon (IFN) response, an i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31a396bc7a41b47b6893e98087d73781
Autor:
Antonio Carlos Manucci
Publikováno v:
Biblioteca Digital de Teses e Dissertações da USP
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
A sinalização da matriz extracelular (MEC) é essencial para a determinação do destino e comportamento de células epiteliais da glândula mamária. Entretanto, pouco é conhecido sobre os mecanismos moleculares envolvidos nesse processo. A via H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fe6cc00a8ab0ee885150d861fc4c6ba
https://doi.org/10.11606/d.46.2019.tde-04072019-085934
https://doi.org/10.11606/d.46.2019.tde-04072019-085934
Autor:
Kelli Cristina Micocci, Araceli Cristina Durante, Antonio Carlos Manucci Pereira, Cyntia de Freitas Montenegro, Heloisa S. Selistre-de-Araujo
Publikováno v:
Cancer Research. 73:B44-B44
Vascular endothelial growth factor (VEGF) and αvβ3 integrin are key molecules that actively participate in tumor angiogenesis and metastasis. Some integrin-blocking molecules are currently under clinical trials for cancer and metastasis treatment.