Zobrazeno 1 - 10
of 233
pro vyhledávání: '"Antonio C, Boschero"'
Autor:
Lucas Zangerolamo, Marina Carvalho, Leticia Barssotti, Gabriela M. Soares, Carine Marmentini, Antonio C. Boschero, Helena Cristina L. Barbosa
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Aging is associated with glucose metabolism disturbances, such as insulin resistance and hyperinsulinemia, which contribute to the increased prevalence of type 2 diabetes (T2D) and its complications in the elderly population. In this sense,
Externí odkaz:
https://doaj.org/article/9d5be515a41c4d45a78aba432cdbadbe
Autor:
Lucas Zangerolamo, Carina Solon, Gabriela M. Soares, Daiane F. Engel, Licio A. Velloso, Antonio C. Boschero, Everardo M. Carneiro, Helena Cristina L. Barbosa
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Alzheimer’s disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia. While cognitive deficits remain the major manifestation of AD, metabolic and non-cognitive abnormalities, such as alterations in fo
Externí odkaz:
https://doaj.org/article/2c61b77f8c9148aebe97d15fc402b853
Autor:
Carine Marmentini, Gabriela M. Soares, Gabriela A. Bronczek, Silvano Piovan, Cecília E. Mareze-Costa, Everardo M. Carneiro, Antonio C. Boschero, Mirian A. Kurauti
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Hyperinsulinemia is frequently associated with aging and may cause insulin resistance in elderly. Since insulin secretion and clearance decline with age, hyperinsulinemia seems to be maintained, primarily, due to a decrease in the insulin clearance.
Externí odkaz:
https://doaj.org/article/f2767730900143c5bcafdabeff01275e
Autor:
Sandra M. Ferreira, José M. Costa-Júnior, Mirian A. Kurauti, Nayara C. Leite, Fernanda Ortis, Luiz F. Rezende, Helena C. Barbosa, Antonio C. Boschero, Gustavo J. Santos
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
ARHGAP21 is a RhoGAP protein implicated in the modulation of insulin secretion and energy metabolism. ARHGAP21 transient-inhibition increase glucose-stimulated insulin secretion (GSIS) in neonatal islets; however, ARHGAP21 heterozygote mice have a re
Externí odkaz:
https://doaj.org/article/fdc07da93c1544ea8351cc27ecaffc88
Autor:
José Maria Costa-Júnior, Sandra Mara Ferreira, Mirian Ayumi Kurauti, Diana L. Bernstein, Elena G. Ruano, Vasumathi Kameswaran, Jonathan Schug, Ricardo Freitas-Dias, Claudio C. Zoppi, Antonio C. Boschero, Camila A. M. de Oliveira, Gustavo J. Santos, Everardo M. Carneiro, Klaus H. Kaestner
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 1, p 1 (2021)
Background/Aims: Epigenetic regulation is considered the main molecular mechanism underlying the developmental origin of health and disease’s (DOHAD) hypothesis. Previous studies that have investigated the role of paternal exercise on the metabolic
Externí odkaz:
https://doaj.org/article/dff57914ff284388b99358575521857d
Publikováno v:
Journal of Cellular Physiology. 237:1119-1142
Islet amyloid polypeptide (IAPP or amylin) is a hormone co-secreted with insulin by pancreatic β-cells and is the major component of islet amyloid. Islet amyloid is found in the pancreas of patients with type 2 diabetes (T2D) and may be involved in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3775745b18e17b9a13b09d17de9946f
https://doi.org/10.1002/jcp.30600
https://doi.org/10.1002/jcp.30600
Autor:
CRISTIANA S.B. SALVATIERRA, SÍLVIA R.L. REIS, ANA F.M. PESSOA, LETÍCIA M.I. DE SOUZA, LUIZ F. STOPPIGLIA, ROBERTO V. VELOSO, MARISE A.B. REIS, EVERARDO M. CARNEIRO, ANTONIO C. BOSCHERO, EDSON M. COLODEL, VANESSA C. ARANTES, MÁRCIA Q. LATORRACA
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 87, Iss 2, Pp 1007-1018 (2015)
The phosphatidylinositol 3-kinase and mitogen-activated protein kinase pathways mediate β cell growth, proliferation, survival and death. We investigated whether protein restriction during pregnancy alters islet morphometry or the expression and pho
Externí odkaz:
https://doaj.org/article/c0470ea9e5b540ebb90022d7cbaeb145
Autor:
Allan Cezar Faria Araujo, Carla Bruna Pietrobon, Gabriela Moreira Soares, Iala Milene Bertasso, Antonio C. Boschero, Rosane Aparecida Ribeiro, Maria Lúcia Bonfleur, Ana Claudia Paiva Alegre-Maller, Sandra Lucinei Balbo, Ana Tereza Bittencourt Guimarães, Janaina Chaves de Oliveira
Publikováno v:
Journal of Developmental Origins of Health and Disease. 13:263-273
Maternal obesity increases the risk of nonalcoholic fatty liver disease (NAFLD) in offspring. The Roux-en-Y gastric bypass (RYBG) is effective for achieving weight loss and ameliorates NAFLD. To determine whether these benefits are maintained after p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2829c768796944df413e108d2a31f4dd
https://doi.org/10.1017/s2040174421000271
https://doi.org/10.1017/s2040174421000271
Autor:
Emílio Marconato-Júnior, Lucas Zangerolamo, Antonio C. Boschero, Jean Franciesco Vettorazzi, Gabriela Alves Bronczek, Carine Marmentini, Jaqueline Fernandes de Barros, Gabriela Moreira Soares, Mirian Ayumi Kurauti, José M. Costa-Júnior
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Scientific Reports
Scientific Reports
Resistance exercise exerts beneficial effects on glycemic control, which could be mediated by exercise-induced humoral factors released in the bloodstream. Here, we used C57Bl/6 healthy mice, submitted to resistance exercise training for 10 weeks. Tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20421550c6d31730cdcdd53bd90a900d
https://doaj.org/article/171b23e3289a4af4880b949fc27e88b4
https://doaj.org/article/171b23e3289a4af4880b949fc27e88b4
Autor:
Mirian A Kurauti, Ricardo Freitas-Dias, Sandra M Ferreira, Jean F Vettorazzi, Tarlliza R Nardelli, Hygor N Araujo, Gustavo J Santos, Everardo M Carneiro, Antonio C Boschero, Luiz F Rezende, José M Costa-Júnior
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0160239 (2016)
The effects of exercise on insulin clearance and IDE expression are not yet fully elucidated. Here, we have explored the effect of acute exercise on insulin clearance and IDE expression in lean mice. Male Swiss mice were subjected to a single bout of
Externí odkaz:
https://doaj.org/article/6e483a6754274371a90ef65c60c84ecf