Ex Vivo Permeation of Carprofen Vehiculated by PLGA Nanoparticles through Porcine Mucous Membranes and Ophthalmic Tissues

Autor: Lídia Gómez-Segura, Alexander Parra, Ana Cristina Calpena-Campmany, Álvaro Gimeno, Immaculada Gómez de Aranda, Antonio Boix-Montañes

Publikováno v: Nanomaterials, Vol 10, Iss 2, p 355 (2020)

(1) Background: Carprofen (CP), 2-(6-chlorocarbazole) propionic acid, is used as an anti-inflammatory, analgesic and anti-pyretic agent and it belongs to the family of non-steroidal anti-inflammatory drugs (NSAIDs). CP has some adverse reactions in s

Externí odkaz: https://doaj.org/article/cdbd0bfc3741492eb0b81ff719fc1961

Clotrimazole multiple W/O/W emulsion as anticandidal agent: Characterization and evaluation on skin and mucosae

Autor: Beatriz Clares-Naveros, Joaquim Suñer-Carbó, Lyda Halbaut-Bellowa, Ana C. Calpena-Campmany, Eliana B. Souto, Nuria Bozal-de Febrer, José L. Soriano-Ruiz, Antonio Boix-Montañes

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Clotrimazole (CLT) was formulated in a multiple W/O/W emulsion (ME) with the aim of evaluating its potential as topical anticandidal agent and comparing with marketed products. A previously evaluated CLT-ME was selected and physicochemically characte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b610910e45f08b182983dc9efade23f
https://doi.org/10.1016/j.colsurfb.2018.11.070

Pharmacokinetic Appraisal of Carprofen Delivery from Intra-Articular Nanoparticles: A Population Modeling Approach in Rabbits

Autor: Helena Colom, Ana C. Calpena, Alexander Parra-Coca, Antonio Boix-Montañes

Publikováno v: Repositorio Institucional UDCA
Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
instacron:Universidad de Ciencias Aplicadas y Ambientales U.D.C.A

Osteoarthritis is frequently treated in veterinary settings with non-steroidal anti-inflammatory drugs (NSAID) such as carprofen (CP). Its action over the articular cartilage can be enhanced by increasing drug uptake into the cartilage, alongside its

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d7ef1a22414b3d01a39ca3a79e68e2c
https://www.mdpi.com/2504-3900/78/1/11

Carprofen Permeation Test through Porcine Ex Vivo Mucous Membranes and Ophthalmic Tissues for Tolerability Assessments : Validation and Histological Study

Autor: Antonio Boix-Montañes, Ana C. Calpena, Lidia Gómez-Segura, Álvaro Gimeno, Alexander Parra

Publikováno v: Veterinary Sciences
Dipòsit Digital de la UB
Universidad de Barcelona
Volume 7
Issue 4
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Repositorio Institucional UDCA
Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
instacron:Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
Veterinary Sciences, Vol 7, Iss 152, p 152 (2020)

Carprofen (CP), a non-steroidal anti-inflammatory drug (NSAID), is profusely used in veterinary medicine for its analgesic and anti-inflammatory activity. Some undesirable effects are associated with its systemic administration. Alternative local rou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba6d06562f9a054020d93ab7b3beb45
https://ddd.uab.cat/record/252980

Pranoprofen quantification in ex vivo corneal and scleral permeation samples: Analytical validation

Autor: G. Abrego, Helen L. Alvarado, Ana C. Calpena-Campmany, C. Cañadas-Enrich, Antonio Boix-Montañes

Publikováno v: Journal of pharmaceutical and biomedical analysis. 160

The investigation of the ocular permeability and/or distribution of pranoprofen (PF), a non-steroidal antiinflamatory drug, demands for the selective analysis of its transit through specific ocular membranes. Therefore, customised ex vivo permeation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b81664bea58ec4a1c59b46e348f8f1a9
https://pubmed.ncbi.nlm.nih.gov/30077069