Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Antonio Barquilla"'
Autor:
Simon Schenk, Matthew R. Bliss, Thomas D.Y. Chung, Janna Kiselar, Michael P Hedrick, Tomas Mustelin, Laurie A. Bankston, Fusayo Yamamoto, Vida Zhang, Jiwen Zou, Jinghua Yu, Yingge Liu, Stephanie M. Stanford, Andrey A. Bobkov, Robert Ardecky, Nunzio Bottini, Antonio Barquilla, Shilpi Khare, Gregory W. Cadwell, Alexander E. Aleshin, Anthony B. Pinkerton, Santhi Ganji, Robert C. Liddington
Publikováno v:
Nature chemical biology, vol 13, iss 6
Obesity-associated insulin resistance plays a central role in type 2 diabetes. As such, tyrosine phosphatases that dephosphorylate the insulin receptor (IR) are potential therapeutic targets. The low-molecular-weight protein tyrosine phosphatase (LMP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c1031f609979e1dab8e8a9ec92ae41
https://escholarship.org/uc/item/2ck6d6dq
https://escholarship.org/uc/item/2ck6d6dq
Autor:
Laurence M. Brill, Susanne Heynen-Genel, Antonio Barquilla, Ilaria Lamberto, Roberta Noberini, Elena B. Pasquale
Publikováno v:
Molecular Biology of the Cell
The EphA2 receptor plays multiple roles in cancer through two distinct signaling mechanisms. In a novel cross-talk, the β2-adrenoceptor/cAMP/PKA axis can promote EphA2 pro-oncogenic, ligand-independent signaling, blocking cell repulsion induced by l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96dfb062865e0554273c321b17d0c8af
https://pubmed.ncbi.nlm.nih.gov/27385333
https://pubmed.ncbi.nlm.nih.gov/27385333
Publikováno v:
Proceedings of the National Academy of Sciences. 105:14579-14584
Target of rapamycin (TOR) kinases control cell growth through two functionally distinct multiprotein complexes. TOR complex 1 (TORC1) controls temporal cell growth and is sensitive to rapamycin, whereas TOR complex 2 (TORC2) is rapamycin resistant an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3196e1529b6439008e1242ce2a0d4554
https://doi.org/10.1073/pnas.0802668105
https://doi.org/10.1073/pnas.0802668105
Autor:
Elena B. Pasquale, Antonio Barquilla
Publikováno v:
Annual review of pharmacology and toxicology. 55
The erythropoietin-producing hepatocellular carcinoma (Eph) receptor tyrosine kinase family plays important roles in developmental processes, adult tissue homeostasis, and various diseases. Interaction with Eph receptor-interacting protein (ephrin) l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c7a7299e377ac12f50063b7989cc74b
https://pubmed.ncbi.nlm.nih.gov/25292427
https://pubmed.ncbi.nlm.nih.gov/25292427
Autor:
Rosario Diaz-Gonzalez, Jean-Mathieu Bart, Manuel Saldivia, Antonio Barquilla, Michael N. Hall, Miguel Navarro
Publikováno v:
Biochemical Society transactions. 41(4)
The complex life cycle of Trypanosoma brucei provides an excellent model system to understand signalling pathways that regulate development. We described previously the classical functions of TOR (target of rapamycin) 1 and TOR2 in T. brucei. In a mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0a9849bdb720c2a1db98510b2586e00
https://pubmed.ncbi.nlm.nih.gov/23863159
https://pubmed.ncbi.nlm.nih.gov/23863159
Autor:
Rosario Diaz, Manuel Saldivia, Miguel Navarro, Jean-Mathieu Bart, Enrique Calvo, Isabel Vidal, Antonio Barquilla, Michael N. Hall
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
African trypanosomes are protozoan parasites transmitted by a tsetse fly vector to a mammalian host. The life cycle includes highly proliferative forms and quiescent forms, the latter being adapted to host transmission. The signaling pathways control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53960ff1ae4dd5f56224c7663a41bede
https://pubmed.ncbi.nlm.nih.gov/22908264
https://pubmed.ncbi.nlm.nih.gov/22908264
Autor:
Miguel Navarro, Wendell Girard-Dias, Antonio Barquilla, Paul N. Ulrich, Roberto Docampo, Sergio Schenkman, Kildare Miranda, Leonardo Augusto, Renata Rosito Tonelli, Veronica Jimenez, Sheila Cristina Nardelli, Maria Cristina M. Motta, Teresa Cristina Leandro de Jesus
Publikováno v:
Repositório Institucional da UNIFESP
Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
Repositório Institucional do INMETRO
Instituto Nacional de Metrologia, Qualidade e Tecnologia (INMETRO)
instacron:INMETRO
Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
Repositório Institucional do INMETRO
Instituto Nacional de Metrologia, Qualidade e Tecnologia (INMETRO)
instacron:INMETRO
National Institutes of Health Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ) Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Ellison Medic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::994fca74d62f18d9f840a8c8519d0da8
http://repositorio.unifesp.br/handle/11600/32734
http://repositorio.unifesp.br/handle/11600/32734
Autor:
Antonio Barquilla, Miguel Navarro
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
TOR (target of rapamycin) is a kinase of the phosphatidylinositol kinase-related kinase (PIKK) family that controls cell growth in eukaryotes in response to nutrients, energy conditions and growth factors. We have recently identified two trypanosome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e1a575d2d5def45520f4068bb883a52
https://pubmed.ncbi.nlm.nih.gov/19221474
https://pubmed.ncbi.nlm.nih.gov/19221474