Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Antonio Artigues"'
Autor:
Giselle Sanchez-Guerrero, David S. Umbaugh, Abhay A. Ramachandran, Antonio Artigues, Hartmut Jaeschke, Anup Ramachandran
Publikováno v:
Livers, Vol 4, Iss 1, Pp 15-30 (2023)
The adenosine A2B receptor (A2BAR) is a member of a family of G-protein coupled receptors (GPCRs), which has a low affinity for adenosine and is now implicated in several pathophysiological conditions. We have demonstrated the beneficial effects of A
Externí odkaz:
https://doaj.org/article/ceb664350c874129ba3fca2decf832c9
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 1, Pp 39-59 (2023)
Background & Aims: Alcohol-associated liver disease (ALD) comprises a spectrum of disorders including steatosis, steatohepatitis, fibrosis, and cirrhosis. We aimed to study the role of protein arginine methyltransferase 6 (PRMT6), a new regulator of
Externí odkaz:
https://doaj.org/article/b3fd6441e4e84cd5b53fa3e81ad3b00d
Publikováno v:
Hepatology Communications, Vol 5, Iss 5, Pp 812-829 (2021)
Protein arginine methyl transferase 1 (PRMT1) is the main enzyme for cellular arginine methylation. It regulates many aspects of liver biology including inflammation, lipid metabolism, and proliferation. Previously we identified that PRMT1 is necessa
Externí odkaz:
https://doaj.org/article/21275645364f4de099762dd1e6ac4ee0
Autor:
Rajan A. Burt, Ibtihal M. Alghusen, Sophiya John Ephrame, Maria T. Villar, Antonio Artigues, Chad Slawson
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
O-GlcNAc is a pleotropic, enigmatic post-translational modification (PTM). This PTM modifies thousands of proteins differentially across tissue types and regulates diverse cellular signaling processes. O-GlcNAc is implicated in numerous diseases, and
Externí odkaz:
https://doaj.org/article/fb8e90d1223d45bb9aa50d239ea75abf
Autor:
Cristian Oliver, Mauricio A. Hernández, Julia I. Tandberg, Karla N. Valenzuela, Leidy X. Lagos, Ronie E. Haro, Patricio Sánchez, Pamela A. Ruiz, Constanza Sanhueza-Oyarzún, Marcos A. Cortés, María T. Villar, Antonio Artigues, Hanne C. Winther-Larsen, Ruben Avendaño-Herrera, Alejandro J. Yáñez
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 7 (2017)
Piscirickettsia salmonis is the predominant bacterial pathogen affecting the Chilean salmonid industry. This bacterium is the etiological agent of piscirickettsiosis, a significant fish disease. Membrane vesicles (MVs) released by P. salmonis deliver
Externí odkaz:
https://doaj.org/article/61229a396f434c13b6a2e4196f8460cb
Autor:
Sushma Jadalannagari, Gabriel Converse, Christopher McFall, Eric Buse, Michael Filla, Maria T Villar, Antonio Artigues, Adam J Mellot, Jinxi Wang, Michael S Detamore, Richard A Hopkins, Omar S Aljitawi
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172098 (2017)
In tissue engineering, an ideal scaffold attracts and supports cells thus providing them with the necessary mechanical support and architecture as they reconstruct new tissue in vitro and in vivo. This manuscript details a novel matrix derived from d
Externí odkaz:
https://doaj.org/article/6e3e70fd48b545e4952c98025725084a
Autor:
Jephte Yao Akakpo, Matthew Wolfgang Jaeschke, Yasaman Etemadi, Antonio Artigues, Scott Toerber, Hernando Olivos, Bindesh Shrestha, Anthony Midey, Hartmut Jaeschke, Anup Ramachandran
Publikováno v:
Journal of the American Society for Mass Spectrometry. 33(11)
Acetaminophen (APAP) overdose is the most common cause of acute liver failure in the US, and hepatotoxicity is initiated by a reactive metabolite which induces characteristic centrilobular necrosis. The only clinically available antidote is
Autor:
Jahaun Azadmanesh, Mohamed A. Seleem, Lucas Struble, Nicholas A. Wood, Derek J. Fisher, Jeffrey J. Lovelace, Antonio Artigues, Aron W. Fenton, Gloria E.O. Borgstahl, Scot P. Ouellette, Martin Conda-Sheridan
Publikováno v:
The Journal of biological chemistry. 299(1)
Chlamydia trachomatis (ct) is the most reported bacterial sexually transmitted infection worldwide and the leading cause of preventable blindness. Caseinolytic proteases (ClpP) from pathogenic bacteria are attractive antibiotic targets, particularly
Publikováno v:
Cellular and molecular gastroenterology and hepatology. 15(1)
Alcohol-associated liver disease (ALD) comprises a spectrum of disorders including steatosis, steatohepatitis, fibrosis, and cirrhosis. We aimed to study the role of protein arginine methyltransferase 6 (PRMT6), a new regulator of liver function, in
Autor:
Braelyn M. Page, Tyler A. Martin, Collette L. Wright, Lauren A. Fenton, Maite T. Villar, Qingling Tang, Antonio Artigues, Audrey Lamb, Aron W. Fenton, Liskin Swint‐Kruse
Publikováno v:
Protein Sci
Various protein properties are often illuminated using sequence comparisons of protein homologs. For example, in analyses of the pyruvate kinase multiple sequence alignment, the set of positions that changed during speciation (“phylogenetic” posi