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Autor:
Stephen Futterweit, John E. Bylander, Roy Mathew, Howard Trachtman, Antonio A. Tarectecan, Judith S. Bond, Elsa Valderrama
Publikováno v:
American Journal of Physiology-Renal Physiology. 289:F911-F921
Meprin (MEP) A is a metalloendopeptidase that is present in the renal proximal tubule brush-border membrane (BBM) and that colocalizes with angiotensin-converting enzyme (ACE). The MEP beta-chain gene locus on chromosome 18 has been linked to a heigh