Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Antonio A Hanson"'
The aryl hydrocarbon receptor in β-cells mediates the effects of TCDD on glucose homeostasis in mice
Autor:
Myriam P. Hoyeck, Ma. Enrica Angela Ching, Lahari Basu, Kyle van Allen, Jana Palaniyandi, Ineli Perera, Emilia Poleo-Giordani, Antonio A. Hanson, Peyman Ghorbani, Morgan D. Fullerton, Jennifer E. Bruin
Publikováno v:
Molecular Metabolism, Vol 81, Iss , Pp 101893- (2024)
Objective: Chronic exposure to persistent organic pollutants (POPs) is associated with increased incidence of type 2 diabetes, hyperglycemia, and poor insulin secretion in humans. Dioxins and dioxin-like compounds are a broad class of POPs that exert
Externí odkaz:
https://doaj.org/article/5118b2da76354e0c9b01b46be2a881b9
Autor:
Evgenia Fadzeyeva, Cassandra A.A. Locatelli, Natasha A. Trzaskalski, My-Anh Nguyen, Megan E. Capozzi, Branka Vulesevic, Nadya M. Morrow, Peyman Ghorbani, Antonio A. Hanson, Ilka Lorenzen-Schmidt, Mary-Anne Doyle, Richard Seymour, Elodie M. Varin, Morgan D. Fullerton, Jonathan E. Campbell, Erin E. Mulvihill
Publikováno v:
iScience, Vol 26, Iss 5, Pp 106748- (2023)
Summary: Mice systemically lacking dipeptidyl peptidase-4 (DPP4) have improved islet health, glucoregulation, and reduced obesity with high-fat diet (HFD) feeding compared to wild-type mice. Some, but not all, of this improvement can be linked to the
Externí odkaz:
https://doaj.org/article/213537b074c74de6ba1a3b4427a6b586
Autor:
Natasha A. Trzaskalski, Branka Vulesevic, My-Anh Nguyen, Natasha Jeraj, Evgenia Fadzeyeva, Nadya M. Morrow, Cassandra A.A. Locatelli, Nicole Travis, Antonio A. Hanson, Julia R.C. Nunes, Conor O’Dwyer, Jelske N. van der Veen, Ilka Lorenzen-Schmidt, Rick Seymour, Serena M. Pulente, Andrew C. Clément, Angela M. Crawley, René L. Jacobs, Mary-Anne Doyle, Curtis L. Cooper, Kyoung-Han Kim, Morgan D. Fullerton, Erin E. Mulvihill
Publikováno v:
JCI Insight, Vol 8, Iss 2 (2023)
Elevated circulating dipeptidyl peptidase-4 (DPP4) is a biomarker for liver disease, but its involvement in gluconeogenesis and metabolic associated fatty liver disease progression remains unclear. Here, we identified that DPP4 in hepatocytes but not
Externí odkaz:
https://doaj.org/article/40cdcc7f6d5742ecbe16d60323de171c
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Enteroendocrine cells directly integrate signals of nutrient content within the gut lumen with distant hormonal responses and nutrient disposal via the production and secretion of peptides, including glucose-dependent insulinotropic polypeptide (GIP)
Externí odkaz:
https://doaj.org/article/c1e861226b464be39ed7810bb2e08f43
Autor:
Elodie M. Varin, Antonio A. Hanson, Jacqueline L. Beaudry, My-Anh Nguyen, Xiemin Cao, Laurie L. Baggio, Erin E. Mulvihill, Daniel J. Drucker
Publikováno v:
JCI Insight, Vol 5, Iss 16 (2020)
Postprandial triglycerides (TGs) are elevated in people with type 2 diabetes (T2D). Glucose-lowering agents, such as glucagon-like peptide-1 (GLP-1) receptor agonists and dipeptidyl peptidase-4 (DPP-4) inhibitors, also reduce postprandial TG excursio
Externí odkaz:
https://doaj.org/article/e1f3441765654638b3479d74a6662d27
Autor:
Myriam P Hoyeck, Rayanna C Merhi, Cameron Tulloch, Kaitlyn McCormick, Shahen Mohammed Abu Hossain, Antonio A Hanson, Jennifer E Bruin
Publikováno v:
Toxicological Sciences.
Epidemiological studies report associations between early-life exposure to persistent organic pollutants (POPs) and impaired metabolic homeostasis in adulthood. We investigated the impact of early-life exposure to low-dose 2,3,7,8-tetrachlorodibenzo-
Autor:
Nadya M. Morrow, Natasha A. Trzaskalski, Antonio A. Hanson, Evgenia Fadzeyeva, Dawn E. Telford, Sanjiv S. Chhoker, Brian G. Sutherland, Jane Y. Edwards, Murray W. Huff, Erin E. Mulvihill
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42:127-144
Objective: Nobiletin is a dietary flavonoid that improves insulin resistance and atherosclerosis in mice with metabolic dysfunction. Dysregulation of intestinal lipoprotein metabolism contributes to atherogenesis. The objective of the study was to de
Autor:
Natasha A, Trzaskalski, Branka, Vulesevic, My-Anh, Nguyen, Natasha, Jeraj, Evgenia, Fadzeyeva, Nadya M, Morrow, Cassandra Aa, Locatelli, Nicole, Travis, Antonio A, Hanson, Julia Rc, Nunes, Conor, O'Dwyer, Jelske N, Van der Veen, Ilka, Lorenzen-Schmidt, Rick, Seymour, Serena M, Pulente, Andrew C, Clément, Angela M, Crawley, René L, Jacobs, Mary-Anne, Doyle, Curtis L, Cooper, Kyoung-Han, Kim, Morgan D, Fullerton, Erin E, Mulvihill
Publikováno v:
JCI insight.
Elevated circulating dipeptidyl-peptidase 4 is a biomarker for liver disease, but its involvement in gluconeogenesis and in metabolic-associated fatty liver disease (MAFLD) progression remains unclear. Here we identified that DPP4 in hepatocytes but
Autor:
Nadya Morrow, Natasha A Trzaskalski, Antonio A Hanson, Cassandra A Locatelli, Serena M Pulente, Erin E Mulvihill
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
Introduction: The small intestine receives hormonal and neuronal stimuli to ensure sufficient nutrient absorption to fuel the body. Insulin resistance promotes aberrant dietary fat delivery into circulation, increasing the risk of cardiovascular dise
Autor:
Nadya M. Morrow, Cassandra A.A. Locatelli, Natasha A. Trzaskalski, Chelsea T. Klein, Antonio A. Hanson, Hadeel Alhadi, Ishika Tripathi, Andrew C. Clément, Sara Imran, Ilka Lorenzen-Schmidt, Erin E. Mulvihill
Publikováno v:
Biochimica et biophysica acta. Molecular and cell biology of lipids. 1867(11)
The small intestine is a highly adaptable organ serving as both a barrier to the external environment and a conduit for nutrient absorption. Enterocytes package dietary triglycerides (TG) into chylomicrons for transport into circulation; the remainin