Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Antonio, Musio"'
Autor:
Maddalena Di Nardo, Simonetta Astigiano, Silvia Baldari, Maria Michela Pallotta, Giovanni Porta, Simona Pigozzi, Annalisa Antonini, Laura Emionite, Annalisa Frattini, Roberto Valli, Gabriele Toietta, Silvia Soddu, Antonio Musio
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-13 (2024)
Abstract Background SMC1A is a subunit of the cohesin complex that participates in many DNA- and chromosome-related biological processes. Previous studies have established that SMC1A is involved in cancer development and in particular, is overexpress
Externí odkaz:
https://doaj.org/article/1d93f6b1d4f7484da2cd34effd3e7fc0
Publikováno v:
Cells, Vol 13, Iss 23, p 2025 (2024)
Cornelia de Lange syndrome (CdLS) is a rare, dominantly inherited multisystem developmental disorder. Pathogenic variants in genes encoding the structural subunits and regulatory proteins of the cohesin complex (NIPBL, SMC1A, SMC3, HDAC8, and RAD21)
Externí odkaz:
https://doaj.org/article/7332f69eb20f4c82938c0b19bca8b37e
Publikováno v:
Cells, Vol 13, Iss 7, p 608 (2024)
Cohesin is a highly conserved ring-shaped complex involved in topologically embracing chromatids, gene expression regulation, genome compartmentalization, and genome stability maintenance. Genomic analyses have detected mutations in the cohesin compl
Externí odkaz:
https://doaj.org/article/b52750eaa6894a518c5c106ebd7b0436
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-11 (2022)
Abstract The cohesin complex controls faithful chromosome segregation by pairing sister chromatids after DNA replication until mitosis. In addition, it is crucial for hierarchal three-dimensional organization of the genome, transcription regulation a
Externí odkaz:
https://doaj.org/article/9d54806884c14fed838a63b7cd7b41ad
Autor:
Marcello D’Andrea, Antonio Musio, Roberto Colasanti, Lorenzo Mongardi, Dalila Fuschillo, Giorgio Lofrese, Luigino Tosatto
Publikováno v:
Frontiers in Surgery, Vol 10 (2023)
BackgroundMicroanastomosis is a challenging technique requiring continuous training to be mastered. Several models have been proposed, but few effectively reflect a real bypass surgery; even fewer are reusable, most are not easily accessible, and the
Externí odkaz:
https://doaj.org/article/0d7a2862f86a4359b34ee0248d2e19bd
Autor:
Marta Gil-Salvador, Ana Latorre-Pellicer, Cristina Lucia-Campos, María Arnedo, María Teresa Darnaude, Aránzazu Díaz de Bustamante, Rebeca Villares, Carmen Palma Milla, Beatriz Puisac, Antonio Musio, Feliciano J. Ramos, Juan Pié
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Ultimate advances in genetic technologies have permitted the detection of transmitted cases of congenital diseases due to parental gonadosomatic mosaicism. Regarding Cornelia de Lange syndrome (CdLS), up to date, only a few cases are known to follow
Externí odkaz:
https://doaj.org/article/9d4e6302de974b37b68d6ed677076a23
Autor:
Patrizia Sarogni, Orazio Palumbo, Adele Servadio, Simonetta Astigiano, Barbara D’Alessio, Veronica Gatti, Dubravka Cukrov, Silvia Baldari, Maria Michela Pallotta, Paolo Aretini, Felice Dell’Orletta, Silvia Soddu, Massimo Carella, Gabriele Toietta, Ottavia Barbieri, Gabriella Fontanini, Antonio Musio
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-16 (2019)
Abstract Background Cancer cells are characterized by chromosomal instability (CIN) and it is thought that errors in pathways involved in faithful chromosome segregation play a pivotal role in the genesis of CIN. Cohesin forms a large protein ring th
Externí odkaz:
https://doaj.org/article/0414178f31f14431b00819e5f7abf6df
Autor:
Marco La Grua, Gianfranco Sindaco, Matteo Zanella, Irene Grazzini, Antonio Musio, Alberto Merlini, Valentina Paci, Simone Vigneri, Carmela Bertone, Gilberto Pari
Publikováno v:
OBM Neurobiology. :1-10
This study aims to determine if high-voltage PRF could effectively adjunct epidural adhesiolysis (EA) in treating patients with chronic lumbosacral radiating pain (LSRP) and neuropathic characteristics. A total of 409 patients suffering from a single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e877d158360c3bcb4a8995bdef3836e
https://doi.org/10.21926/obm.neurobiol.2302171
https://doi.org/10.21926/obm.neurobiol.2302171
Autor:
Chue Vin Chin, Jisha Antony, Sarada Ketharnathan, Anastasia Labudina, Gregory Gimenez, Kate M Parsons, Jinshu He, Amee J George, Maria Michela Pallotta, Antonio Musio, Antony Braithwaite, Parry Guilford, Ross D Hannan, Julia A Horsfield
Publikováno v:
eLife, Vol 9 (2020)
Mutations in genes encoding subunits of the cohesin complex are common in several cancers, but may also expose druggable vulnerabilities. We generated isogenic MCF10A cell lines with deletion mutations of genes encoding cohesin subunits SMC3, RAD21,
Externí odkaz:
https://doaj.org/article/468478a941f34ce89b0313a4e6cc727f
Autor:
Marcello D’Andrea, Lorenzo Mongardi, Francesco Cultrera, Dalila Fuschillo, Simone Peraio, Paul Roblot, Antonio Musio, Luigino Tosatto, Flavio Giordano
Publikováno v:
Pediatric Neurosurgery. 57:389-395
Background: Acute traumatic epidural hematoma (EDH) is a complication in 2–3% of pediatric head injuries. Surgery is mandatory in symptomatic cases; otherwise, conservative treatment is a valid approach, especially in the pediatric population. Ossi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05791a2f195bb5f0bec9b92f840ae294
https://doi.org/10.1159/000527241
https://doi.org/10.1159/000527241