Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Antonio, Conconi"'
Autor:
Laetitia Guintini, Audrey Paillé, Marco Graf, Brian Luke, Raymund J Wellinger, Antonio Conconi
Publikováno v:
PLoS Genetics, Vol 18, Iss 4, p e1010167 (2022)
Ultraviolet light causes DNA lesions that are removed by nucleotide excision repair (NER). The efficiency of NER is conditional to transcription and chromatin structure. UV induced photoproducts are repaired faster in the gene transcribed strands tha
Externí odkaz:
https://doaj.org/article/d356cfd42acf4603a46d51ecc0eb0c6f
Autor:
Audrey Paillé, Romain Charton, Alexia Muguet, Joachim Griesenbeck, Michael J. Smerdon, Antonio Conconi
Publikováno v:
Data in Brief, Vol 25, Iss , Pp - (2019)
The existence of two chromatin structures in the rDNA locus was previously demonstrated for a large variety of organisms, ranging from yeast to human. In yeast there are about 150–200 rRNA genes organized in tandem repeats. Almost half of them are
Externí odkaz:
https://doaj.org/article/1afa47d988fa43dfb76a2699c9d87099
Autor:
Laetitia Guintini, Audrey Paillé, Marco Graf, Brian Luke, Raymund J. Wellinger, Antonio Conconi
Publikováno v:
PLoS genetics. 18(4)
Ultraviolet light causes DNA lesions that are removed by nucleotide excision repair (NER). The efficiency of NER is conditional to transcription and chromatin structure. UV induced photoproducts are repaired faster in the gene transcribed strands tha
Publikováno v:
Photochemistry and photobiologyREFERENCES. 98(3)
The yeast rDNA locus is a suitable model to study nucleotide excision repair (NER) in chromatin. A portion of rRNA genes is transcribed and largely depleted of nucleosomes, the remaining genes are not transcribed and folded in nucleosomes. In G1-arre
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 815:20-29
Hydroxyurea (HU) is an inhibitor of ribonucleotide reductase that is used as a chemotherapeutic agent to treat a number of chronic diseases. Addition of HU to cell cultures causes reduction of the dNTP cellular pool below levels that are required for
Autor:
François Peyresaubes, Antonio Conconi, Romain Charton, Carlos Zeledon, Alexia Muguet, Laetitia Guintini
Publikováno v:
Photochemistry and Photobiology. 93:363-374
If not repaired, ultraviolet light-induced DNA damage can lead to genome instability. Nucleotide excision repair (NER) of UV photoproducts is generally fast in the coding region of genes, where RNA polymerase-II (RNAP2) arrest at damage sites and tri
Autor:
Alexia Muguet, Antonio Conconi, Michael J. Smerdon, Romain Charton, Joachim Griesenbeck, Audrey Paillé
Publikováno v:
Data in Brief, Vol 25, Iss, Pp-(2019)
The existence of two chromatin structures in the rDNA locus was previously demonstrated for a large variety of organisms, ranging from yeast to human. In yeast there are about 150–200 rRNA genes organized in tandem repeats. Almost half of them are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88232d35ac735182ce2221390f15425c
https://europepmc.org/articles/PMC6595284/
https://europepmc.org/articles/PMC6595284/
Nucleosome positioning, nucleotide excision repair and photoreactivation in Saccharomyces cerevisiae
Publikováno v:
DNA Repair. 36:98-104
The position of nucleosomes on DNA participates in gene regulation and DNA replication. Nucleosomes can be repressors by limiting access of factors to regulatory sequences, or activators by facilitating binding of factors to exposed DNA sequences on
Autor:
Annie D’AmoursA. D’Amours, Antonio Conconi, Frédéric Leduc, Guylain Boissonneault, François Peyresaubes, Marie-Chantal Grégoire
Publikováno v:
DNA repair. 36
A strategy amenable to the genome-wide study of DNA damage and repair kinetics is described. The ultraviolet damage endonuclease (UVDE) generates 3'-OH ends at the two major UV induced DNA lesions, cyclobutane pyrimidine dimers (CPDs) and 6,4 pyrimid
Autor:
Brendan Bell, Antonio Conconi
Publikováno v:
Nature. 545:165-166
Ultraviolet light can damage DNA, triggering a general shutdown of gene transcription — yet some genes are activated by UV light. An investigation of this counter-intuitive behaviour reveals a surprising gene-regulation mechanism.