Growing the molecular architecture of imidazole-like ligands in HO-1 complexes

Autor: Floresta, Giuseppe, Fallica, Antonino N., Salerno, Loredana, Sorrenti, Valeria, Pittalà, Valeria, Rescifina, Antonio

Publikováno v: In Bioorganic Chemistry December 2021 117

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Gut microbiota in symptomatic uncomplicated diverticular disease stratifies by severity of abdominal pain.

Autor: Tursi A; Territorial Gastroenterology Service, Barletta-Andria-Trani Local Health Agency, Andria.; Department of Medical and Surgical Sciences, School of Medicine, Catholic University, Rome., Turroni S; Unit of Microbiome Science and Biotechnology, Department of Pharmacy and Biotechnology, University of Bologna, Bologna., De Bastiani R; GIGA-CP Italian Association for Primary Care Gastroenterology, Feltre., Procaccianti G; Unit of Microbiome Science and Biotechnology, Department of Pharmacy and Biotechnology, University of Bologna, Bologna., D'Amico F; Unit of Microbiome Science and Biotechnology, Department of Pharmacy and Biotechnology, University of Bologna, Bologna., Allegretta L; Division of Gastroenterology, 'Santa Caterina Novella' Hospital, Galatina., Antonino N; General Pratictioner, Private Practice Gastroenterologist, Bisceglie.; Barletta-Andria-Trani Local Health Agency, Andria., Baldi E; GIGA-CP Italian Association for Primary Care Gastroenterology, Feltre., Casamassima C; Barletta-Andria-Trani Local Health Agency, Andria.; General Pratictioner, Private Practice Gastroenterologist, San Ferdinando di Puglia., Casella G; GIGA-CP Italian Association for Primary Care Gastroenterology, Feltre., Ciuffi M; GIGA-CP Italian Association for Primary Care Gastroenterology, Feltre., De Bastiani M; GIGA-CP Italian Association for Primary Care Gastroenterology, Feltre., Lazzarotto L; GIGA-CP Italian Association for Primary Care Gastroenterology, Feltre., Licci C; Private Practice Gastroenterologist, Monopoli., Mancuso M; GIGA-CP Italian Association for Primary Care Gastroenterology, Feltre., Penna A; Private Practice Gastroenterologist, Bari., Pranzo G; Ambulatory for IBD Treatment, 'Valle D'Itria' Hospital, Martina Franca., Sanna G; GIGA-CP Italian Association for Primary Care Gastroenterology, Feltre., Tosetti C; GIGA-CP Italian Association for Primary Care Gastroenterology, Feltre., Zamparella M; GIGA-CP Italian Association for Primary Care Gastroenterology, Feltre., Picchio M; Division of Surgery, 'P. Colombo' Hospital, Rome, Italy.

Publikováno v: European journal of gastroenterology & hepatology [Eur J Gastroenterol Hepatol] 2025 Feb 01; Vol. 37 (2), pp. 147-153. Date of Electronic Publication: 2024 Nov 07.

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Discovery of Novel Acetamide-Based Heme Oxygenase-1 Inhibitors with Potent In Vitro Antiproliferative Activity

Autor: Agata Grazia D’Amico, Giuseppe Romeo, Velia D'Agata, Loredana Salerno, Antonio Rescifina, Sebastiano Intagliata, Valeria Consoli, Valeria Pittalà, Giuseppe Floresta, Antonino N. Fallica, Valeria Sorrenti, Luca Vanella

Publikováno v: Journal of Medicinal Chemistry. 64:13373-13393

Heme oxygenase-1 (HO-1) promotes heme catabolism exercising cytoprotective roles in normal and cancer cells. Herein, we report the design, synthesis, molecular modeling, and biological evaluation of novel HO-1 inhibitors. Specifically, an amide linke

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cf40ba282c95b3b81206731b7af06a6
https://doi.org/10.1021/acs.jmedchem.1c00633