Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Antonina Y Alexandrova"'
Autor:
Antonina Y Alexandrova, Katya Arnold, Sébastien Schaub, Jury M Vasiliev, Jean-Jacques Meister, Alexander D Bershadsky, Alexander B Verkhovsky
Publikováno v:
PLoS ONE, Vol 3, Iss 9, p e3234 (2008)
Dynamic actin network at the leading edge of the cell is linked to the extracellular matrix through focal adhesions (FAs), and at the same time it undergoes retrograde flow with different dynamics in two distinct zones: the lamellipodium (peripheral
Externí odkaz:
https://doaj.org/article/e49fc3e84bc24eb19cb071b92308b1c7
Autor:
Aleksandra S. Chikina, Anna O. Zholudeva, Maria E. Lomakina, Igor I. Kireev, Alexander A. Dayal, Alexander A. Minin, Mathieu Maurin, Tatyana M. Svitkina, Antonina Y. Alexandrova
Publikováno v:
Cells, Vol 13, Iss 1, p 105 (2024)
The formation of specific cellular protrusions, plasma membrane blebs, underlies the amoeboid mode of cell motility, which is characteristic for free-living amoebae and leukocytes, and can also be adopted by stem and tumor cells to bypass unfavorable
Externí odkaz:
https://doaj.org/article/b5bc7033d81c4f7792df5472e0b5a111
Autor:
Anna O. Zholudeva, Maria E. Lomakina, Evgeniya A. Orlova, Yanan Wang, Artem I. Fokin, Anna Polesskaya, Alexis M. Gautreau, Antonina Y. Alexandrova
Publikováno v:
Biochemistry (Moscow). 87:1651-1661
Autor:
Ali Dayoub, Artem I. Fokin, Maria E. Lomakina, John James, Marina Plays, Tom Jacquin, Nikita M. Novikov, Rostislav S. Vorobyov, Anastasia A. Schegoleva, Karina D. Rysenkova, Julia Gaboriaud, Sergey V. Leonov, Evgeny V. Denisov, Alexis M. Gautreau, Antonina Y. Alexandrova
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 1; Pages: 313
Whole exome sequencing of invasive mammary carcinomas revealed the association of mutations in PTEN and ZFHX3 tumor suppressor genes (TSGs). We generated single and combined PTEN and ZFHX3 knock-outs (KOs) in the immortalized mammary epithelial cell
Autor:
Ivan A. Vorobjev, Daria M. Potashnikova, Svetlana N. Rubtsova, Antonina Y. Alexandrova, Aleksandra S. Chikina, Maria E. Lomakina
Publikováno v:
Biology of the Cell. 111:245-261
Background information Metastatic disease is caused by the ability of cancer cells to reach distant organs and form secondary lesions at new locations. Dissemination of cancer cells depends on their migration plasticity - an ability to switch between
Publikováno v:
Int Rev Cell Mol Biol
International Review of Cell and Molecular Biology ISBN: 9780128212837
International Review of Cell and Molecular Biology ISBN: 9780128212837
During development of metastasis, tumor cells migrate through different tissues and encounter different extracellular matrices. An ability of cells to adapt mechanisms of their migration to these diverse environmental conditions, called migration pla
Publikováno v:
The Journal of Cell Biology
Chikina et al. show preferential initiation of blebbing at local cytoskeleton weaknesses at filopodial bases when blebbing is induced by Arp2/3 complex inhibition. They also use correlative platinum replica electron microscopy to characterize actin c
Publikováno v:
Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology. 11:35-47
The abilities of tumor cells to invade and metastasize are frequent causes of death of cancer patients. Studying the mechanisms of cell motility alterations and acquisition of enhanced metastatic potential as the result of transformation is an import
Autor:
Antonina Y. Alexandrova, Thierry Dubois, Ivan Bièche, Sophie Vacher, Maria E. Lomakina, Nicolas Molinie, Leanne de Koning, Irene Dang, Wulfran Cacheux, François Lallemand, Alexis Gautreau, V. D. Ermilova, Tamara A. Chipysheva
Publikováno v:
British Journal of Cancer
Background: The Arp2/3 complex is required for cell migration and invasion. The Arp2/3 complex and its activators, such as the WAVE complex, are deregulated in diverse cancers. Here we investigate the expression of Arpin, the Arp2/3 inhibitory protei
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1749
During the last few years, significant attention has been given to the plasticity of cell migration, i.e., the ability of individual cell to switch between different motility modes, in particular between mesenchymal and amoeboid motilities. This phen