Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Antonina V, Pustovidko"'
Autor:
Inna I. Severina, A. G. Rogov, Tatiana A. Trendeleva, Antonina V. Pustovidko, Tatiana I. Rokitskaya, Vladimir P. Skulachev, Yuri N. Antonenko, Renata A. Zvyagilskaya, Ruben A. Simonyan, Boris V. Chernyak, Konstantin G. Lyamzaev
Publikováno v:
Mitochondrion. 13:520-525
Previously it has been shown by our group that berberine and palmatine, penetrating cations of plant origin, when conjugated with plastoquinone (SkQBerb and SkQPalm), can accumulate in isolated mitochondria or in mitochondria of living cells and effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90d8346faa7edc80851bd228e62c560c
https://doi.org/10.1016/j.mito.2012.09.006
https://doi.org/10.1016/j.mito.2012.09.006
Autor:
Irina G, Shabalina, Mikhail Yu, Vyssokikh, Natalia, Gibanova, Robert I, Csikasz, Daniel, Edgar, Anne, Hallden-Waldemarson, Zinaida, Rozhdestvenskaya, Lora E, Bakeeva, Valeria B, Vays, Antonina V, Pustovidko, Maxim V, Skulachev, Barbara, Cannon, Vladimir P, Skulachev, Jan, Nedergaard
Publikováno v:
Aging (Albany NY)
MtDNA mutator mice exhibit marked features of premature aging. We find that these mice treated from age of ≈100 days with the mitochondria-targeted antioxidant SkQ1 showed a delayed appearance of traits of aging such as kyphosis, alopecia, lowering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6965d588c083535493188b946334cd20
https://pubmed.ncbi.nlm.nih.gov/28209927
https://pubmed.ncbi.nlm.nih.gov/28209927
Autor:
Antonina V. Pustovidko, Lidia V. Domnina, Ruben A. Simonyan, Boris V. Chernyak, Natalia V. Sumbatyan, Vitaly A. Roginsky, Galina A. Korshunova, Maxim V. Skulachev, Vladimir P. Skulachev, Tatyana I. Rokitskaya, Yuriy N. Antonenko, Konstantin G. Lyamzaev, O. Y. Ivanova, Vadim N. Tashlitsky, Inna I. Severina
Publikováno v:
Pharmaceutical Research. 28:2883-2895
To develop effective mitochondria-targeted antioxidants composed entirely of natural constituents.Novel mitochondria-targeted antioxidants were synthesized containing plant electron carrier and antioxidant plastoquinone conjugated by nonyloxycarbonyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae01d4ed0e2ab342fa8d4e68634c680a
https://doi.org/10.1007/s11095-011-0504-8
https://doi.org/10.1007/s11095-011-0504-8
Autor:
Fedor F. Severin, Galina A. Korshunova, Antonina V. Pustovidko, Maxim V. Skulachev, Dmitry A. Cherepanov, Nataliya V. Sumbatyan, Mikhail Yu. Vyssokikh, Lev S. Yaguzhinsky, Tatiana I. Rokitskaya, Vladimir P. Skulachev, Elena N. Mokhova, Inna I. Severina, Yury N. Antonenko, Olga V. Markova
Publikováno v:
Proceedings of the National Academy of Sciences. 107:663-668
A unique phenomenon of mitochondria-targeted protonophores is described. It consists in a transmembrane H + -conducting fatty acid cycling mediated by penetrating cations such as 10-(6’-plastoquinonyl)decyltriphenylphosphonium (SkQ1) or dodecyltrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dee9c9f59c3f36843e959e08df1c8a3
https://doi.org/10.1073/pnas.0910216107
https://doi.org/10.1073/pnas.0910216107
Autor:
Antonina V. Pustovidko, Jan Nedergaard, Mikhail Yu. Vyssokikh, Maxim V. Skulachev, Natalia Gibanova, Barbara Cannon, Irina G. Shabalina, Robert I. Csikasz, Vladimir P. Skulachev, Daniel Edgar
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1857:e121
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::068676598afc6f29521b83fe3379e7aa
https://doi.org/10.1016/j.bbabio.2016.04.260
https://doi.org/10.1016/j.bbabio.2016.04.260
Autor:
Galina Shagieva, Boris V. Chernyak, Inna I. Severina, D. S. Izyumov, Tatyana I. Rokitskaya, T. A. Trendeleva, Vadim N. Tashlitsky, Lidia V. Domnina, Vera Dugina, A. G. Rogov, E. Titova, Ruben A. Simonyan, Evgeniy R. Galimov, Yuri N. Antonenko, Maxim V. Skulachev, Antonina V. Pustovidko, Renata A. Zvyagilskaya, O. Yu. Ivanova, Konstantin G. Lyamzaev
Publikováno v:
Biochemistry. Biokhimiia. 77(9)
Novel mitochondria-targeted compounds composed entirely of natural constituents have been synthesized and tested in model lipid membranes, in isolated mitochondria, and in living human cells in culture. Berberine and palmatine, penetrating cations of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6990b443b5bfcc061c4be267a3108e48
https://pubmed.ncbi.nlm.nih.gov/23157257
https://pubmed.ncbi.nlm.nih.gov/23157257
Autor:
Inna I. Severina, Fedor F. Severin, Dmitry A. Knorre, Olga V. Markova, Irina V. Perevoshchikova, Dmitry A. Cherepanov, Natalia V. Sumbatyan, Alexander A. Sobko, Antonina V. Pustovidko, Ruben A. Simonyan, Tatyana I. Rokitskaya, Galina A. Korshunova, A. V. Avetisyan, Yuri N. Antonenko, Vladimir P. Skulachev, Silvia M. Ojovan, Ekaterina A. Smirnova
A limited decrease in mitochondrial membrane potential can be beneficial for cells, especially under some pathological conditions, suggesting that mild uncouplers (protonophores) causing such an effect are promising candidates for therapeutic uses. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de4553925b3e79d0b953411da68f7b61
https://europepmc.org/articles/PMC3093858/
https://europepmc.org/articles/PMC3093858/
Autor:
Fedor F. Severin, Tatyana I. Rokitskaya, Yuri N. Antonenko, Inna I. Severina, Vladimir P. Skulachev, Antonina V. Pustovidko, Alexander A. Sobko
Publikováno v:
Biophysical Journal. 100(3)
Mild uncoupling of mitochondria assumes that partial decrease in membrane potential is beneficial for cells especially under some pathological conditions, suggesting that uncouplers are good candidates for therapeutic uses. The majority of known prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f078e111340d9da6114a989c42886fb0
Autor:
O. Yu. Pletjushkina, Lora E. Bakeeva, Tatyana I. Rokitskaya, Antonina V. Pustovidko, Maxim V. Skulachev, Vadim N. Tashlitsky, Boris V. Chernyak, D. S. Izyumov, A. V. Avetisyan, A. A. Pashkovskaya, Yuri N. Antonenko, Maria S. Muntyan, I. V. Skulachev, Lev S. Yaguzhinsky, Vyacheslav A. Chertkov, Galina A. Korshunova, Vladimir P. Skulachev, Vitaly A. Roginsky, Inna I. Severina, Khailova Ls, O. K. Nepryakhina, J. M. Vassiliev, I. V. Sviryaeva, O. Yu. Ivanova, Andrey A. Zamyatnin, Konstantin G. Lyamzaev, V. B. Saprunova, Enno K. Ruuge, Natalia V. Sumbatyan, M. Yu. Vyssokikh, S.S. Klishin, Lidia V. Domnina, Ruben A. Simonyan
Publikováno v:
Biochemistry. Biokhimiia. 73(12)
Synthesis of cationic plastoquinone derivatives (SkQs) containing positively charged phosphonium or rhodamine moieties connected to plastoquinone by decane or pentane linkers is described. It is shown that SkQs (i) easily penetrate through planar, mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::255137b4b39b6b92d80d6311f45be84e
https://pubmed.ncbi.nlm.nih.gov/19120014
https://pubmed.ncbi.nlm.nih.gov/19120014
Autor:
Barbara Cannon, Nils-Göran Larsson, Antonina V. Pustovidko, Jan Nedergaard, Irina G. Shabalina, Mikhail Yu. Vyssokikh, Vladimir P. Skulachev, Daniel Edgar
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1777
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e4fcfe5a4d1452b21fc2ea027f5edd6