Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Antonina Rait"'
Autor:
Manish Moghe, Sang-Soo Kim, Miaoyin Guan, Antonina Rait, Kathleen F. Pirollo, Joe B. Harford, Esther H. Chang
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 14, p 7539 (2024)
Due to their inhibition of acetylcholinesterase, organophosphates are among the most toxic of chemicals. Pralidoxime (a.k.a 2-PAM) is the only acetylcholinesterase reactivator approved in the U.S., but 2-PAM only poorly traverses the blood–brain ba
Externí odkaz:
https://doaj.org/article/fa479bdacb484acfb87478c121a16f22
Nanomedicine-Based Gene Delivery for a Truncated Tumor Suppressor RB94 Promotes Lung Cancer Immunity
Autor:
Sang-Soo Kim, Caroline Doherty, Manish Moghe, Antonina Rait, Kathleen F. Pirollo, Joe B. Harford, Esther H. Chang
Publikováno v:
Cancers, Vol 14, Iss 20, p 5092 (2022)
Because lung cancer remains the most common and lethal of cancers, novel therapeutic approaches are urgently needed. RB94 is a truncated form of retinoblastoma tumor suppressor protein with elevated anti-tumor efficacy. Our investigational nanomedici
Externí odkaz:
https://doaj.org/article/4cef55a5a3304bc3849a5ff634644fde
Publikováno v:
OncoImmunology, Vol 7, Iss 10 (2018)
The tumor suppressor p53 responds to genotoxic and oncogenic stresses by inducing cell cycle arrest and apoptosis. Recent studies suggest that p53 also participates in the regulation of cellular immune responses. Here, we have investigated the potent
Externí odkaz:
https://doaj.org/article/bb4300d60ed1479ba1938f754e3a5d91
Autor:
Carter Van Waes, Zhong Chen, Esther H. Chang, Kathleen F. Pirollo, Antonina Rait, Sang S. Kim, Andrew D. Cherniack, Steven J. M. Jones, A. Gordon Robertson, Richard V. Smith, Geoffrey J. Childs, Michael B. Prystowsky, Thomas M. Harris, Ludmila Danilova, Douglas Chepeha, Jamie Couper, Shaleeka Cornelius, Rita Das, Xinping Yang, Paul E. Clavijo, Sophie Carlson, Pinar Ormanoglu, Han Si, Scott E. Martin, Hui Cheng, Anthony D. Saleh
Supplementary Table S1, S3-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1463f964ae20d5f34b195246d4276602
https://doi.org/10.1158/1078-0432.22474164.v1
https://doi.org/10.1158/1078-0432.22474164.v1
Autor:
Carter Van Waes, Zhong Chen, Esther H. Chang, Kathleen F. Pirollo, Antonina Rait, Sang S. Kim, Andrew D. Cherniack, Steven J. M. Jones, A. Gordon Robertson, Richard V. Smith, Geoffrey J. Childs, Michael B. Prystowsky, Thomas M. Harris, Ludmila Danilova, Douglas Chepeha, Jamie Couper, Shaleeka Cornelius, Rita Das, Xinping Yang, Paul E. Clavijo, Sophie Carlson, Pinar Ormanoglu, Han Si, Scott E. Martin, Hui Cheng, Anthony D. Saleh
Purpose:To identify deregulated and inhibitory miRNAs and generate novel mimics for replacement nanomedicine for head and neck squamous cell carcinomas (HNSCC).Experimental Design:We integrated miRNA and mRNA expression, copy number variation, and DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75c37363704fa2cc03491970fe6ae179
https://doi.org/10.1158/1078-0432.c.6528702.v1
https://doi.org/10.1158/1078-0432.c.6528702.v1
Autor:
Carter Van Waes, Zhong Chen, Esther H. Chang, Kathleen F. Pirollo, Antonina Rait, Sang S. Kim, Andrew D. Cherniack, Steven J. M. Jones, A. Gordon Robertson, Richard V. Smith, Geoffrey J. Childs, Michael B. Prystowsky, Thomas M. Harris, Ludmila Danilova, Douglas Chepeha, Jamie Couper, Shaleeka Cornelius, Rita Das, Xinping Yang, Paul E. Clavijo, Sophie Carlson, Pinar Ormanoglu, Han Si, Scott E. Martin, Hui Cheng, Anthony D. Saleh
Supplementary Methods, References, Figure legends, Table S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a7a3051d75b38d5dbd304d45ce18bc
https://doi.org/10.1158/1078-0432.22474158
https://doi.org/10.1158/1078-0432.22474158
Autor:
Carter Van Waes, Scott E. Martin, Antonina Rait, Anthony Saleh, Geoffrey J. Childs, Thomas M. Harris, Pinar Ormanoglu, Rita Das, Andrew D. Cherniack, Jamie Couper, Michael B. Prystowsky, A. Gordon Robertson, Hui Cheng, Douglas B. Chepeha, Esther H. Chang, Shaleeka Cornelius, Zhong Chen, Sang S. Kim, Ludmila Danilova, Richard V. Smith, Han Si, Kathleen F. Pirollo, Sophie Carlson, Steven J.M. Jones, Paul E. Clavijo, Xinping Yang
Publikováno v:
Clin Cancer Res
Purpose: To identify deregulated and inhibitory miRNAs and generate novel mimics for replacement nanomedicine for head and neck squamous cell carcinomas (HNSCC). Experimental Design: We integrated miRNA and mRNA expression, copy number variation, and
Autor:
Gabriel Lopez-Berestein, Ke Liang, Farwah Rubab, Cristian Coarfa, Esther H. Chang, Anadulce Hernandez-Herrera, Preethi H. Gunaratne, Chunru Lin, Anil K. Sood, Amy C. Rowat, Avinashnarayan Venkatanarayan, Lingegowda S. Mangala, Elsa R. Flores, Ashley Benham, Kimal Rajapakshe, Abhi K. Rao, Sang-Soo Kim, Yinghong Pan, Antonina Rait, Kathleen F. Pirollo, Clara K. Chan
Publikováno v:
Cancer
Cancer, vol 125, iss 14
Cancer, vol 125, iss 14
Background Over 96% of high‐grade ovarian carcinomas and 50% of all cancers are characterized by alterations in the p53 gene. Therapeutic strategies to restore and/or reactivate the p53 pathway have been challenging. By contrast, p63, which shares
Autor:
Kathleen F. Pirollo, Joe B. Harford, Manish Moghe, Esther H. Chang, Antonina Rait, Sang-Soo Kim
Publikováno v:
Nucleic Acids Research
Intrinsic therapeutic resistance especially in cancer stem cells (CSCs) together with extensive tumor cell infiltration and restricted permeation of the blood-brain barrier (BBB) by drugs may all contribute to the treatment failure in patients with g
Publikováno v:
Immune Aspects of Biopharmaceuticals and Nanomedicines ISBN: 9780203731536
Immune Aspects of Biopharmaceuticals and Nanomedicines
Immune Aspects of Biopharmaceuticals and Nanomedicines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe8917f7b6d048f38e463f30f3a4eefa
https://doi.org/10.1201/b22372-30
https://doi.org/10.1201/b22372-30