Impact of Donor-Specific anti-HLA antibodies and donor KIR characteristics in haploidentical HSCT for beta-Thalassemia

Autor: Marco Andreani, Manuela Testi, Pietro Sodani, Maria Troiano, Andrea Di Luzio, Giuseppe Testa, Michela Falco, Elvira Poggi, Javid Gaziev, Antonina Piazza

Publikováno v: Mediterranean Journal of Hematology and Infectious Diseases, Vol 9, Iss 1, Pp e2017020-e2017020 (2017)

In the present study we investigated the role of donor specific HLA antibodies (DSA) and donor KIR repertoire characteristics in a group of 18 patients affected by haemoglobinopathies who underwent haploidentical T cell depleted transplantation. Amon

Externí odkaz: https://doaj.org/article/a4b21f9f7f0f459cb69c53def6690bce

Acute kidney transplant rejection mediated by angiotensin II type 1 receptor antibodies in a pediatric hyperimmune patient

Autor: Luca Dello Strologo, Francesca Diomedi Camassei, Elvira Poggi, Isabella Guzzo, Antonina Piazza, Federica Morolli

Publikováno v: Pediatric nephrology (Berl. West) 32 (2017): 185–188. doi:10.1007/s00467-016-3500-8
info:cnr-pdr/source/autori:Guzzo I.; Morolli F.; Camassei F.D.; Piazza A.; Poggi E.; Dello Strologo L./titolo:Acute kidney transplant rejection mediated by angiotensin II type 1 receptor antibodies in a pediatric hyperimmune patient/doi:10.1007%2Fs00467-016-3500-8/rivista:Pediatric nephrology (Berl. West)/anno:2017/pagina_da:185/pagina_a:188/intervallo_pagine:185–188/volume:32

Background: Several cases of severe antibody-mediated rejection (AMR) secondary to antibodies against the angiotensin II type 1 receptor (AT1R-Ab) have been described with variable outcome. Case-Diagnosis/Treatment: We report the case of a 13-year-ol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71bf697916bd64167340755c7e27106c
https://doi.org/10.1007/s00467-016-3500-8

PRE-TRANSPLANT HLA ANTIBODY SCREENING BY SOLID PHASE ASSAYS: INCIDENCE OF ANTI-HLA IGM ANTIBODIES IN KIDNEY TRANSPLANT CANDIDATES

Autor: Elvira Poggi, Giuseppina Ozzella, Antonio Giuseppe Bianculli, Annarita Manfreda, Lucia Spano, Damiano Colasante, Maria Rosaria Fazio, Silvia Sinopoli, Antonina Piazza.

Publikováno v: 1st European Immunogenetics and Histocompatibility Conference (EFI) 25th Annual Meeting of the German Society for Immunogenetics (DGI) 30 May-2 June 2017, pp. 389–390, Mannheim/Heidelberg, Germany, 30/05/2017-2/06/2017
info:cnr-pdr/source/autori:Elvira Poggi, Giuseppina Ozzella, Antonio Giuseppe Bianculli, Annarita Manfreda, Lucia Spano, Damiano Colasante, Maria Rosaria Fazio, Silvia Sinopoli, Antonina Piazza./congresso_nome:1st European Immunogenetics and Histocompatibility Conference (EFI) 25th Annual Meeting of the German Society for Immunogenetics (DGI) 30 May-2 June 2017/congresso_luogo:Mannheim%2FHeidelberg, Germany/congresso_data:30%2F05%2F2017-2%2F06%2F2017/anno:2017/pagina_da:389/pagina_a:390/intervallo_pagine:389–390

A positive lymphocytotoxic crossmatch represents an absolute contraindication to kidney transplantation. This paradigm is widely accepted for IgG antibodies but few data on the clinical relevance of IgM antibodies are available and so their role is s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::574dd8f68d5498355242b8c18d512e9e
http://www.cnr.it/prodotto/i/429277

Renal transplantation in sensitized children and young adults: a nationwide approach

Autor: Annalisa Maria Valeria Pipicelli, Fabrizio Ginevri, Sara Testa, A. Ricci, Germana Longo, Isabella Guzzo, Luisa Murer, Luca Dello Strologo, Elisa Benetti, Luciana Ghio, Federica Morolli, Alessandro Nanni Costa, Antonina Piazza, Massimo Cardillo

Publikováno v: Nephrology, dialysis, transplantation
32 (2017): 191–195. doi:10.1093/ndt/gfw369
info:cnr-pdr/source/autori:Dello Strologo L.D.; Murer L.; Guzzo I.; Morolli F.; Pipicelli A.M.V.; Benetti E.; Longo G.; Testa S.; Ricci A.; Ginevri F.; Ghio L.; Cardillo M.; Piazza A.; Costa A.N./titolo:Renal transplantation in sensitized children and young adults: A nationwide approach/doi:10.1093%2Fndt%2Fgfw369/rivista:Nephrology, dialysis, transplantation (Print)/anno:2017/pagina_da:191/pagina_a:195/intervallo_pagine:191–195/volume:32

Background. High levels of preformed anti-HLA antibodies dramatically diminish renal transplant outcomes.Most desensitization programmes guarantee good intermediate outcomes but quite disappointing long-term prognosis. The search for a fully compatib

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be2f278d9f1a860aa90b9b475f7f2163
https://pubmed.ncbi.nlm.nih.gov/27742824

Post-transplant development of C1q-positive HLA antibodies and kidney graft survival

Autor: Antonina, Piazza, Elvira, Poggi, Giuseppina, Ozzella, Domenico, Adorno

Publikováno v: Clinical transplants.

The development of de novo human leukocyte antigen (HLA) donor specific antibodies (DSA), detected by both cytotoxic or solid phase assays, was considered the major risk factor for allograft failure in kidney transplantation. However, it was shown th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::305c5c16ed79c869580a4a8fbc06b78f
https://pubmed.ncbi.nlm.nih.gov/25095531