Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Antonina Pechkovsky"'
Autor:
Miran Aswad, Antonina Pechkovsky, Narmeen Ghanayiem, Haya Hamza, Yaniv Dotan, Igal Louria-Hayon
Publikováno v:
Pharmaceuticals, Vol 17, Iss 10, p 1382 (2024)
Background/Objectives: Asthma is a chronic inflammatory disorder of the airways affecting over 10% of the global population. It is characterized by airway inflammation, mucus hypersecretion, and bronchial hyperresponsiveness, driven predominantly by
Externí odkaz:
https://doaj.org/article/fb1f88305c184926a56de565f75887cd
Autor:
Nicole Paland, Haya Hamza, Antonina Pechkovsky, Miran Aswad, Dayana Shagidov, Igal Louria-Hayon
Publikováno v:
Rambam Maimonides Medical Journal, Vol 14, Iss 4, p e0022 (2023)
Rheumatoid diseases, including rheumatoid arthritis, osteoarthritis, and fibromyalgia, are characterized by progressive inflammation in the musculoskeletal system, predominantly affecting the joints and leading to cartilage and bone damage. The resul
Externí odkaz:
https://doaj.org/article/02f30657f5554b9f82a961ce6a4d9da0
Autor:
Miran Aswad, Haya Hamza, Antonina Pechkovsky, Anastasiia Zikrach, Tania Popov, Yaniv Zohar, Eduardo Shahar, Igal Louria-Hayon
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Cytokine storm refers to the dysregulated production of inflammatory mediators leading to hyperinflammation. They are often detrimental, and worsen the severity of COVID-19 and other infectious or inflammatory diseases. Cannabinoids are known to have
Externí odkaz:
https://doaj.org/article/52085119cda44dcbac2cdf89728935b8
Autor:
Nicole Paland, Antonina Pechkovsky, Miran Aswad, Haya Hamza, Tania Popov, Eduardo Shahar, Igal Louria-Hayon
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Coronavirus disease-19 caused by the novel RNA betacoronavirus SARS-CoV2 has first emerged in Wuhan, China in December 2019, and since then developed into a worldwide pandemic with >99 million people afflicted and >2.1 million fatal outcomes as of 24
Externí odkaz:
https://doaj.org/article/0f382e8b30d84ee98a3e739a76e84981
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 10, Iss 6, Pp 1-14 (2019)
Cell Death and Disease, Vol 10, Iss 6, Pp 1-14 (2019)
The adenovirus (Ad) E4orf4 protein contributes to efficient progression of virus infection. When expressed alone E4orf4 induces p53- and caspase-independent cell-death, which is more effective in cancer cells than in normal cells in tissue culture. C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9906062f340e1575a1de355838414d5
https://doi.org/10.1038/s41419-019-1680-4
https://doi.org/10.1038/s41419-019-1680-4
Publikováno v:
Proceedings of the National Academy of Sciences. 110
The adenovirus E4orf4 protein regulates the progression of viral infection, and when expressed alone in mammalian tissue culture cells it induces protein phosphatase 2A (PP2A)-B55– and Src-dependent cell death, which is more efficient in oncogene-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ab39cf1535c330bcc1d1d90432851c
https://doi.org/10.1073/pnas.1220282110
https://doi.org/10.1073/pnas.1220282110
The adenovirus E4orf4 protein must bind protein phosphatase 2A (PP2A) for its functions.The E4orf4 binding site in PP2A was mapped to the α1,α2 helices of the B55α subunit.The E4orf4 binding site in PP2A-B55α lies above the substrate binding site
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11d9265ccac4b57847f28c0a4f4f875f
https://europepmc.org/articles/PMC3650409/
https://europepmc.org/articles/PMC3650409/
Publikováno v:
Cell Cycle
The adenovirus E4 open reading frame 4 (E4orf4) protein is a multifunctional viral regulator that contributes to temporal regulation of the progression of viral infection. When expressed outside the context of the virus, E4orf4 induces p53-independen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b5beea6da0e1460d0ffca059ccf025d
http://europepmc.org/articles/PMC3841309
http://europepmc.org/articles/PMC3841309