Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Antonin Libra"'
Autor:
Filip Kostelansky, Miroslav Miletin, Zuzana Havlinova, Barbora Szotakova, Antonin Libra, Radim Kucera, Veronika Novakova, Petr Zimcik
Publikováno v:
Nucleic Acids Research. 50:10212-10229
The short oligodeoxynucleotide (ODN) probes are suitable for good discrimination of point mutations. However, the probes suffer from low melting temperatures. In this work, the strategy of using acridine-4-carboxamide intercalators to improve thermal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::077c5ecb3bda4e1ebb877e52bd75993c
https://doi.org/10.1093/nar/gkac777
https://doi.org/10.1093/nar/gkac777
Autor:
Veronika Novakova, Zuzana Havlínová, Miroslav Miletin, Antonin Libra, Jiri Demuth, Petr Zimcik, Ales Ruzicka, Radim Kučera
Publikováno v:
Organic Chemistry Frontiers. 7:445-456
The formation of J-dimers is rarely reported in the scientific literature, even though these architectures often have important consequences for various applications. Octasubstituted azaphthalocyanines (AzaPcs) bearing dialkylamino substituents form
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fd10b242ef5c6080832a3a46c90bd53
https://doi.org/10.1039/c9qo01364d
https://doi.org/10.1039/c9qo01364d
Autor:
Radim Kučera, Antonin Libra, Zuzana Havlínová, Jiri Demuth, Miroslav Miletin, Petr Zimcik, Kamil Kopecky, Veronika Novakova
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 24(38)
Unsymmetrical dialkylamino-substituted zinc azaphthalocyanine (AzaPc) exhibits unique spectral and photophysical properties for dark quenchers of fluorescence in DNA hybridization probes. The panchromatic light absorption of AzaPc from 300 nm up to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f45a86a0430482be7c8c168b5dea08f
https://pubmed.ncbi.nlm.nih.gov/29683215
https://pubmed.ncbi.nlm.nih.gov/29683215
Autor:
Vladimír Velebný, Tomáš Muthný, Antonin Libra, Martina Moravcová, Jana Dvořáková, Lukáš Kubala, Alena Víšková
Publikováno v:
Interdisciplinary Toxicology
Skin exposure to ultraviolet (UV) light evokes a complex stress response in keratinocytes. Keratin filament organization provides structural stability and mechanical integrity of keratinocytes. Involucrin is a transglutaminase substrate protein contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f77ee8c1b6651443737311eb4d40914
https://doi.org/10.2478/intox-2013-0030
https://doi.org/10.2478/intox-2013-0030
Publikováno v:
Reproductive Toxicology. 28:46-51
Placental 11 beta-hydroxysteroid dehydrogenase type 2 (11 beta-HSD2) is the key enzyme which protects the fetus from overexposure to glucocorticoids (GCs) by their oxidation into inactive derivates. Several recent studies suggest that 11 beta-HSD2 ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2ac3220e2ab480e7f5ce0b879e0af73
https://doi.org/10.1016/j.reprotox.2009.02.006
https://doi.org/10.1016/j.reprotox.2009.02.006
Autor:
Claudio Tiribelli, Massimo Visigalli, Vito Lorusso, Frantisek Staud, Lorella Pascolo, Cristina Fernetti, Antonin Libra, Pier Lucio Anelli
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 319:809-817
Contrast-enhanced magnetic resonance imaging (CE-MRI) is a valuable technique for the diagnosis of liver diseases. As gadocoletic acid trisodium salt (B22956/1), a new contrast agent showing high biliary excretion, may be potentially advantageous in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e1b6bf9f79ad4699b474537f8b59852
https://doi.org/10.1124/jpet.106.106591
https://doi.org/10.1124/jpet.106.106591
Autor:
Renate Fuchs, Marianne Brabec, Frantisek Staud, Martina Ceckova, Antonin Libra, Petr Pavek, Petr Nachtigal
Publikováno v:
ResearcherID
1. Breast cancer resistance protein (BCRP, ABCG2) is a drug efflux transporter that is believed to affect the drug disposition of several drugs and xenobiotics. In the present study, we evaluated the localization and functional expression of BCRP in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afcea393956d64f207a9acb653efb610
https://doi.org/10.1111/j.1440-1681.2006.04324.x
https://doi.org/10.1111/j.1440-1681.2006.04324.x
Publikováno v:
Scopus-Elsevier
Decades of liver regeneration studies still left the termination phase least elucidated. However regeneration ending mechanisms are clinicaly relevant. We aimed to analyse the timing and transcriptional control of the latest phase of liver regenerati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58c759816ec98b31d978f3e6cb77d346
https://pubmed.ncbi.nlm.nih.gov/23130906
https://pubmed.ncbi.nlm.nih.gov/23130906
Autor:
Marie Stiborová, Jitka Poljaková, Jan Hraběta, Jana Hřebačková, Zuzana Zemanova, Tomas Eckschlager, Antonin Libra, Martin Bunček, Pavel Prochazka
Publikováno v:
Cancer science. 103(2)
Most high-risk neuroblastomas develop resistance to cytostatics and therefore there is a need to develop new drugs. In previous studies, we found that ellipticine induces apoptosis in human neuroblastoma cells. We also investigated whether ellipticin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e5fe467921e852b2ca775c280a6f912
https://pubmed.ncbi.nlm.nih.gov/22040216
https://pubmed.ncbi.nlm.nih.gov/22040216
Publikováno v:
Acta Medica, Vol 52, Iss 3, Pp 91-99 (2009)
Scopus-Elsevier
Scopus-Elsevier
Liver regeneration in mammals is a unique phenomenon attracting scientific interest for decades. It is a valuable model for basic biology research of cell cycle control as well as for clinically oriented studies of wide and heterogeneous group of liv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42fa37f862d4e4730d1751c66f6cdb5c
https://pubmed.ncbi.nlm.nih.gov/20073420
https://pubmed.ncbi.nlm.nih.gov/20073420